Small Cell Neuroendocrine Carcinoma — Genomics

Small Cell Neuroendocrine Carcinoma — Genomics · CancerIndex

Genomics

Gene alteration frequencies by cohort

4 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.

Small Cell Lung Cancer (CLCGP, Nat Genet 2012) sclc_clcgpCLCGP

29 cases with simple somatic mutation data · 29 cases total · 2026-01-13 · mapped to Lung Small Cell Carcinoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	TP53	Ssm	26	29	89.7%	cbioportal
2	RB1	Ssm	19	29	65.5%	cbioportal
3	LRP1B	Ssm	13	29	44.8%	cbioportal
4	USH2A	Ssm	13	29	44.8%	cbioportal
5	TTN	Ssm	11	29	37.9%	cbioportal
7	PKHD1	Ssm	10	29	34.5%	cbioportal
6	CSMD3	Ssm	10	29	34.5%	cbioportal
8	COL11A1

Data updated 22 days agoSource updated 2026-01-13

Small Cell Lung Cancer (Johns Hopkins, Nat Genet 2012) sclc_jhuJohns Hopkins

80 cases with simple somatic mutation data · 80 cases total · 2026-01-13 · mapped to Lung Small Cell Carcinoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	TP53

Small-Cell Lung Cancer (Multi-Institute, Cancer Cell 2017) sclc_cancercell_gardner_2017Multi-Institute

20 cases with simple somatic mutation data · 20 cases total · 2026-01-13 · mapped to Lung Small Cell Carcinoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	POLE

Small Cell Lung Cancer (U Cologne, Nature 2015) sclc_ucologne_2015U Cologne

120 cases with simple somatic mutation data · 120 cases total · 2026-01-13 · mapped to Lung Small Cell Carcinoma EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	TP53

Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.