Gene
ADAM22
ADAM metallopeptidase domain 22
Explore in graph →CI-GENE-00000426HGNC:201 ENSG00000008277 NCBI 53616 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (9)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 28196596
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Small-Cell Lung Cancer (Multi-Institute, Cancer Cell 2017) sclc_cancercell_gardner_2017 | Lung Small Cell Carcinoma | Ssm | 16 | 20 | 80% | 16 | cbioportal |
| Diffuse Large B-Cell Lymphoma (Broad, PNAS 2012) dlbc_broad_2012 | Diffuse Large B-Cell Lymphoma Unclassifiable | Ssm | 3 | 58 | 5.2% | 130 | cbioportal |
| Mantle Cell Lymphoma (IDIBIPS, PNAS 2013) mcl_idibips_2013 | Mantle Cell Lymphoma | Ssm | 1 | 29 | 3.4% | 38 | cbioportal |
| Gallbladder Carcinoma (Shanghai, Nat Genet 2014) gbc_shanghai_2014 | Gallbladder Carcinoma | Ssm | 1 | 32 | 3.1% | 140 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.