Subtype
Rectal Neoplasm
CI-CAN-00006564Explore in graph →
Non-malignant434 active trials1 approved drugs5 evidence items
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Subtype
CI-CAN-00006564Explore in graph →
Clinical trials
1,773 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT06601985 | Exploring the Effect of Colonic J-pouch in Anorectal Preservation Surgery for Ultra-low Rectal Cancer. | active not recruiting | — | 154 | Shanghai 10th People's HospitalOTHER | 1 | Sep 19, 2024 | clinicaltrials |
| NCT02431676 | Survivorship Promotion In Reducing IGF-1 Trial(SPIRIT) | completed | Phase 2 | 121 | Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsOTHER | 1 | Aug 28, 2024 |
| clinicaltrials |
| NCT06567756 | Conformal Sphincter-Preservation Operation Versus InterSphincteric Resection on Anal Function in Low Rectal Cancer | not yet recruiting | N/A | 84 | Changhai HospitalOTHER | 0 | Aug 23, 2024 | clinicaltrials |
| NCT05086627 | Short-course Radiotherapy Followed by Tislelizumab + CapeOX in the Treatment for Locally Advanced Rectal Cancer | completed | Phase 2 | 118 | Hebei Medical University Fourth HospitalOTHER | 1 | Aug 22, 2024 | clinicaltrials |
| NCT00297791 | COLOR II: Laparoscopic Versus Open Rectal Cancer Removal(COLORII) | completed | Phase 3 | 1,044 | Nova Scotia Health AuthorityOTHER | 9 | Aug 21, 2024 | clinicaltrials |
| NCT05215535 | Liver Magnetic Resonance Imaging Before Treatment for Rectal Cancer. A Randomised Controlled Trial.(Limerick) | recruiting | N/A | 400 | Vastra Gotaland RegionOTHER_GOV | 1 | Aug 19, 2024 | clinicaltrials |
| NCT06540027 | The Effect of Minimally Invasive Surgery on Systemic Inflammatory Response in Rectal Cancer | unknown | — | 80 | Başakşehir Çam & Sakura City HospitalOTHER_GOV | 1 | Aug 15, 2024 | clinicaltrials |
| NCT05130060 | A Vaccine (PolyPEPI1018 Vaccine) and TAS-102 for the Treatment of Metastatic Colorectal Cancer | completed | Phase 1 | 15 | Mayo ClinicOTHER | 1 | Aug 14, 2024 | clinicaltrials |
| NCT06006390 | CEA Targeting Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of CEA Positive Advanced Solid Tumors | unknown | Phase 1 / Phase 2 | 60 | Chongqing Precision Biotech Co., LtdINDUSTRY | 1 | Aug 9, 2024 | clinicaltrials |
| NCT00788957 | Panitumumab Combination Study With Rilotumumab or Ganitumab in Wild-type Kirsten Rat Sarcoma Virus Oncogene Homolog (KRAS) Metastatic Colorectal Cancer (mCRC) | completed | Phase 1 / Phase 2 | 177 | NantBioScience, Inc.INDUSTRY | 0 | Aug 7, 2024 | clinicaltrials |
| NCT03133286 | Radiotherapy Assessments During Intervention ANd Treatment (RADIANT)(RADIANT) | completed | — | 16 | DxTerity DiagnosticsINDUSTRY | 1 | Aug 7, 2024 | clinicaltrials |
| NCT05939687 | Prophylactic Mesh Placement During Stoma Closure After Low Anterior Resection(ProMeLAR) | recruiting | Phase 3 | 142 | Blokhin's Russian Cancer Research CenterOTHER | 1 | Aug 7, 2024 | clinicaltrials |
| NCT06542354 | Prehabilitation During Neoadjuvant Chemoradiotherapy for Rectal Cancer | completed | N/A | 108 | Fudan UniversityOTHER | 1 | Aug 7, 2024 | clinicaltrials |
| NCT04636008 | Sintilimab Plus Hypofractionated Radiotherapy for MSI-H/dMMR Rectal Cancer | unknown | Phase 1 / Phase 2 | 20 | West China HospitalOTHER | 1 | Aug 6, 2024 | clinicaltrials |
| NCT06536712 | Effects of Exosome Adminstration in Preventing Early Leakage in Rectal Cancer Patients Undergoing Low Anterior Resection | unknown | Phase 1 | 20 | Tehran University of Medical SciencesOTHER | 1 | Aug 5, 2024 | clinicaltrials |
| NCT06536127 | Prospective Monocentric Study Evaluating the Circulating NK Cells Phenotype and the ImmunoScore® in Patients With Non Metastatic Rectal Cancer(IMMUNOREC) | recruiting | N/A | 100 | Institut Sainte CatherineOTHER | 1 | Aug 2, 2024 | clinicaltrials |
| NCT06524362 | Effect of Pelvic Rehabilitation After Low Anterior Resection for Cancer Rectum. - A Randomised Controlled Trial(PERECARE) | unknown | N/A | 77 | GEM Hospital & Research CenterOTHER | 1 | Jul 29, 2024 | clinicaltrials |
| NCT06521827 | The Role of Short Course of Palliative Radiation in Metastatic Cancer Rectum | not yet recruiting | N/A | 49 | Assiut UniversityOTHER | 0 | Jul 26, 2024 | clinicaltrials |
| NCT06519006 | Effectiveness of Pelvic Floor Exercise to Prevent LARS (Low Anterior Resection Syndrome)(CH1) | unknown | N/A | 50 | F. D. Roosevelt University HospitalOTHER | 1 | Jul 25, 2024 | clinicaltrials |
| NCT06256055 | Phase 1 Study of UCMYM802 Injection in Mesothelin-positive Advanced Malignant Solid Tumors | unknown | Phase 1 | 24 | UTC Therapeutics Inc.INDUSTRY | 1 | Jul 24, 2024 | clinicaltrials |
| NCT06504875 | Application of PD-1 Monoclonal Antibody in Combination With IL-2 and CapeOX in Organ Preservation Therapy for Ultra-Low Localized Advanced Rectal Cancer | not yet recruiting | — | 23 | The First Affiliated Hospital with Nanjing Medical UniversityOTHER | 0 | Jul 17, 2024 | clinicaltrials |
| NCT04938336 | Evaluation of a Decision Aid Tool in Rectal Cancer patiënts | completed | — | 70 | University Hospital, GhentOTHER | 1 | Jul 11, 2024 | clinicaltrials |
| NCT01171300 | Assessment of Response Before, During and After Neoadjuvant Chemoradiotherapy in Rectal Cancer Patients | unknown | N/A | 94 | Universitaire Ziekenhuizen KU LeuvenOTHER | 1 | Jul 10, 2024 | clinicaltrials |
| NCT06314646 | Transanal Transection and Single-stapled Anastomosis (TTSS) in Rectal Cancer Patients(TTSS-REC) | recruiting | — | 472 | Istituto Clinico HumanitasOTHER | 1 | Jun 27, 2024 | clinicaltrials |
| NCT06326892 | Natural Orifice Specimen Extraction in Low Rectal Cancer Surgery(NOSES) | unknown | — | 350 | Istituto Clinico HumanitasOTHER | 1 | Jun 26, 2024 | clinicaltrials |
| NCT06458725 | Assessment of DW-MRI Measures : Reproducibility and Repeatability in Pelvic Imaging on MR-Linac With Healthy Volunteers(PILLAR) | unknown | N/A | 30 | Jules Bordet InstituteOTHER | 0 | Jun 14, 2024 | clinicaltrials |
| NCT05471401 | GI Organ Tracking Via Balloon Applicators | withdrawn | N/A | 0 | Washington University School of MedicineOTHER | 0 | Jun 13, 2024 | clinicaltrials |
| NCT06455124 | Short-course Radiotherapy Combined With CapeOx and PD-1 Inhibitor After Local Excision for High-risk Early Rectal Cancer (TORCH-LE) | recruiting | Phase 2 | 60 | Fudan UniversityOTHER | 1 | Jun 13, 2024 | clinicaltrials |
| NCT06450574 | Preoperative Chemoradiotherapy and Transanal Endoscopic Microsurgery Versus Ttransanal Endoscopic Microsurgery in T1 N0, M0 Rectal Cancer (TAUTEM-T1 Study)(TAUTEM-T1) | not yet recruiting | Phase 3 | 106 | Corporacion Parc TauliOTHER | 0 | Jun 10, 2024 | clinicaltrials |
| NCT06442215 | Selection of Surgical Technique in Rectal Cancer(TECARE) | unknown | — | 333 | Institut d'Investigació Biomèdica de Girona Dr. Josep TruetaOTHER | 1 | Jun 5, 2024 | clinicaltrials |
| NCT06443671 | Neoadjuvant Fruquintinib Plus Tislelizumab Combined With mCapeOX Versus CapeOX for Mid-high pMMR/MSS Locally Advanced Rectal Cancer(PKUCH-R09) | not yet recruiting | Phase 2 / Phase 3 | 132 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jun 5, 2024 | clinicaltrials |
| NCT06104579 | Concordance Between Monitoring Systems for Organ/Space Surgical Site Infections in Rectal Surgery | completed | — | 11,367 | Hospital de GranollersOTHER | 1 | May 31, 2024 | clinicaltrials |
| NCT06435975 | Physical Activity in Rectal Cancer Survivors | completed | N/A | 20 | Abramson Cancer Center at Penn MedicineOTHER | 1 | May 30, 2024 | clinicaltrials |
| NCT03714490 | MRI Simulation-guided Boost in Short-course Preoperative Radiotherapy for Unresectable Rectal Cancer(SUNRISE) | unknown | Phase 2 | 200 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | May 29, 2024 | clinicaltrials |
| NCT04357587 | Safety and Feasibility of PD-1 Blockade in the Treatment of dMMR or MSI-H Rectal Cancer | completed | Phase 1 | 6 | Case Comprehensive Cancer CenterOTHER | 1 | May 29, 2024 | clinicaltrials |
| NCT03300544 | Talimogene Laherparepvec, Chemotherapy, and Radiation Therapy Before Surgery in Treating Patients With Locally Advanced or Metastatic Rectal Cancer | terminated | Phase 1 | 3 | National Cancer Institute (NCI)NIH | 1 | May 23, 2024 | clinicaltrials |
| NCT03992456 | Panitumumab, Regorafenib, or TAS-102, in Treating Patients With Metastatic and/or Unresectable RAS Wild-Type Colorectal Cancer | unknown | Phase 2 | 12 | Academic and Community Cancer Research UnitedOTHER | 1 | May 21, 2024 | clinicaltrials |
| NCT06164691 | Blue and Amber Light Exposure in Patients With Rectal and Pancreatic Cancer | terminated | N/A | 2 | Matthew Neal MDOTHER | 1 | May 21, 2024 | clinicaltrials |
| NCT05233787 | Trial Evaluating the Tailored Versus the Systematic Use of Defunctioning Stoma After Total Mesorectal Excision for Rectal Cancer (GRECCAR17)(GRECCAR17) | unknown | N/A | 212 | University Hospital, BordeauxOTHER | 1 | May 16, 2024 | clinicaltrials |
| NCT01345175 | Rifaximin and Placebo in the Treatment of Bowel Dysfunction After Anterior Resection for Rectal Cancer | completed | Phase 3 | 69 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | May 14, 2024 | clinicaltrials |
| NCT05927584 | Local Excision for Organ Preservation in Early REctal Cancer With No Adjuvant Treatment(LORENA) | recruiting | — | 145 | Fundación de Investigación Biomédica - Hospital Universitario de La PrincesaOTHER | 1 | May 14, 2024 | clinicaltrials |
| NCT06382415 | Organ/Space Surgical Site Infection and Recurrence and Survival in Rectal Cancer Surgery(VINCat_PDO_2) | completed | — | 3,826 | Hospital de GranollersOTHER | 1 | May 13, 2024 | clinicaltrials |
| NCT06405308 | Robotic Natural Orifice Specimen Extraction Surgery Versus Robotic Transabdominal Specimen Extraction Surgery for Early-Stage Rectal Cancer | completed | — | 636 | Taiyuan LiOTHER | 1 | May 13, 2024 | clinicaltrials |
| NCT04755920 | SGM-101 in Colorectal Brain Metastases.(SGM-CBM) | unknown | Phase 2 | 10 | Leiden University Medical CenterOTHER | 1 | May 9, 2024 | clinicaltrials |
| NCT06404554 | A Prediction Model of Anastomotic Stricture After Rectal Cancer | completed | — | 1,542 | Northern Jiangsu People's HospitalOTHER | 1 | May 8, 2024 | clinicaltrials |
| NCT02022553 | Procedure RACHEL in Complex Treatment of Rectal Cancer(RACHEL) | completed | N/A | 52 | Voronezh N.N. Burdenko State Medical AcademyOTHER | 1 | May 6, 2024 | clinicaltrials |
| NCT02132858 | Genetic Mutations in Blood and Tissue Samples in Predicting Response to Treatment in Patients With Locally Advanced Rectal Cancer Undergoing Chemoradiation | completed | — | 43 | Fox Chase Cancer CenterOTHER | 1 | May 2, 2024 | clinicaltrials |
| NCT06395337 | Multimodal Imaging in Rectal Cancer & Pancreatic Cancer(MIRCA & MIPAC) | unknown | Phase 1 / Phase 2 | 20 | Radboud University Medical CenterOTHER | 1 | May 2, 2024 | clinicaltrials |
| NCT06396975 | Comparison of Short-term Outcomes of Robotic and Laparoscopic Surgery in Patients With Different Body Mass Index for Mid and Low Rectal Cancer | completed | — | 1,413 | Daorong WangOTHER | 1 | May 2, 2024 | clinicaltrials |
| NCT06397053 | Comparison of Robotic Versus Laparoscopic Surgery for Visceral Obesity in Mid-Low Rectal Cancer: A Propensity-Matched Analysis | completed | — | 242 | Daorong WangOTHER | 1 | May 2, 2024 | clinicaltrials |
Data updated 23 days agoSource updated Sep 19, 2024source: clinicaltrials