Subtype
Rectal Neoplasm
CI-CAN-00006564Explore in graph →
Non-malignant434 active trials1 approved drugs5 evidence items
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Subtype
CI-CAN-00006564Explore in graph →
Clinical trials
1,773 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT04205955 | Testing Diet Intervention Versus Non-Diet Intervention for Management of Bowel Symptoms in Rectal Cancer Survivors | completed | Phase 2 | 95 | SWOG Cancer Research NetworkNETWORK | 2 | May 1, 2024 | clinicaltrials |
| NCT06390982 | Organ Preservation With Tislelizumab and Total Neoadjuvant Therapy in Patients With Low Rectal Cancer: RELIEVE -01 Study | not yet recruiting | Phase 2 | 46 | Fudan UniversityOTHER | 0 | Apr 30, 2024 | clinicaltrials |
| NCT06391060 | Gender Differences in Robotic Surgery for Rectal Cancer: a Retrospective Study | completed | — | 155 | Daorong WangOTHER | 1 | Apr 30, 2024 | clinicaltrials |
| NCT05900648 | Regorafenib and XmAb20717 in Treatment of High-risk Patients With Colorectal Cancer With Radiographic Occult Molecular Residual Disease After End of Established Definitive Therapy (RX-CROME) | withdrawn | Phase 2 | 0 | M.D. Anderson Cancer CenterOTHER | 0 | Apr 29, 2024 | clinicaltrials |
| NCT06255379 | Study of Fruquintinib Combined With Tegafur Gimeracil Oteracil in Patients With Metastatic Colorectal Cancer | not yet recruiting | Phase 2 | 52 | Guangzhou University of Traditional Chinese MedicineOTHER | 1 | Apr 29, 2024 | clinicaltrials |
| NCT03402477 | "Watch and Wait" After Neo-adjuvant Chemoradiotherapy for Primary Locally Advanced Rectal Cancer.(NORWAIT) | terminated | — | 86 | Helse Stavanger HFOTHER_GOV | 1 | Apr 24, 2024 | clinicaltrials |
| NCT06380855 | Flexible Colonoscope Assisted Hybrid Transanal Total Mesorectal Resection (taTME) | unknown | — | 5 | Sun Yat-sen UniversityOTHER | 1 | Apr 24, 2024 | clinicaltrials |
| NCT04124601 | Neoadjuvant Chemoradiotherapy With Sequential Ipilimumab and Nivolumab in Rectal Cancer(CHINOREC) | completed | Phase 2 | 80 | Johannes Laengle, MD, PhDOTHER | 1 | Apr 23, 2024 | clinicaltrials |
| NCT05052086 | Magnetomotoric Ultrasound (MMUS) in Rectal Cancer(MAMORECT) | unknown | N/A | 60 | Region SkaneOTHER | 1 | Apr 23, 2024 | clinicaltrials |
| NCT05228431 | Modified Sandwich Therapeutic Regimen for Locally Advanced Rectal Cancer | recruiting | Phase 2 | 121 | Zhen-Hai LuOTHER | 1 | Apr 22, 2024 | clinicaltrials |
| NCT06376227 | Robotic-Assisted or Laparoscopic Radical Resection for Rectal Cancer With or Without Left Colic Artery Preservation | completed | — | 1,164 | Northern Jiangsu People's HospitalOTHER | 1 | Apr 22, 2024 | clinicaltrials |
| NCT06375434 | Correlation Between Gut Microbiota and Radiosensitivity of Rectal Cancer(GMRSC-LARC) | unknown | — | 100 | Jing-kun LiuOTHER | 0 | Apr 19, 2024 | clinicaltrials |
| NCT06369597 | A Randomized Controlled Trial of the Safety and Efficacy of Robotic Telesurgery Versus Laparoscopic Surgery | unknown | N/A | 177 | Sun Yat-sen UniversityOTHER | 1 | Apr 17, 2024 | clinicaltrials |
| NCT01972373 | Visualization of Rectal Cancer During Endoscopy, Using a Fluorescent Tracer(RAPIDO-TRACT) | completed | Phase 1 | 30 | University Medical Center GroningenOTHER | 1 | Apr 16, 2024 | clinicaltrials |
| NCT03465982 | Timing to Minimally Invasive Surgery After Neoadjuvant Chemoradiotherapy for Rectal Cancer(TiMiSNAR) | recruiting | N/A | 340 | Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di AlessandriaOTHER | 1 | Apr 16, 2024 | clinicaltrials |
| NCT03962088 | Timisnar - Biomarkers Substudy (Timisnar-mirna)(TiMiSNAR-miRNA) | unknown | — | 200 | Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di AlessandriaOTHER | 1 | Apr 16, 2024 | clinicaltrials |
| NCT04638036 | Fluorescence Molecular Endoscopy and Molecular Fluorescence-guided Surgery in Locally Advanced Rectal Cancer(TRACT-II) | completed | Phase 1 | 11 | University Medical Center GroningenOTHER | 1 | Apr 16, 2024 | clinicaltrials |
| NCT05356585 | Circulating Tumor DNA to Monitor the Efficacy of Total Neoadjuvant Therapy for Rectal Cancer | withdrawn | — | 0 | Case Comprehensive Cancer CenterOTHER | 1 | Apr 12, 2024 | clinicaltrials |
| NCT03317119 | Trametinib and Trifluridine and Tipiracil Hydrochloride in Treating Patients With Colon or Rectal Cancer That is Advanced, Metastatic, or Cannot Be Removed by Surgery | completed | Phase 1 | 26 | City of Hope Medical CenterOTHER | 1 | Apr 8, 2024 | clinicaltrials |
| NCT05293054 | Healing of Rectal Anastomosis Sealed With a Concentrate Derived From the Patient's Blood, After Rectal Cancer Surgery(OBANORES) | completed | — | 50 | University of AarhusOTHER | 1 | Mar 27, 2024 | clinicaltrials |
| NCT04543695 | A Study of Total Neoadjuvant Therapy for High-risk Locally Advanced Rectal Cancer | unknown | Phase 2 | 255 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Mar 26, 2024 | clinicaltrials |
| NCT06271629 | Impact of Quality of Life in the Patients With Sleep Disturbance From Low Anterior Resection Syndrome in Advanced Rectal Cancer Patients | completed | — | 100 | Seoul National University HospitalOTHER | 1 | Mar 26, 2024 | clinicaltrials |
| NCT05305820 | Perioperative Exercise and Nutritional Optimisation Prehabilitation Before Surgery for Patients With Peritoneal Malignancy(PANO) | unknown | N/A | 36 | Dublin City UniversityOTHER | 1 | Mar 21, 2024 | clinicaltrials |
| NCT05883800 | Total Neoadjuvant Treatment Combined With Adaptive Radiotherapy for Rectal Cancer(TNT-RECORD) | recruiting | N/A | 61 | Haukeland University HospitalOTHER | 1 | Mar 19, 2024 | clinicaltrials |
| NCT06304987 | Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and PCSK9 Inhibitor for pMMR/MSS Locally Advanced Mid-low Rectal Cancer | unknown | Phase 2 | 50 | Beijing Friendship HospitalOTHER | 1 | Mar 19, 2024 | clinicaltrials |
| NCT06318234 | PET/MR Evaluation of Regression Grading After Neoadjuvant Therapy for Rectal Cancer | unknown | — | 32 | Xiao ChenOTHER | 1 | Mar 19, 2024 | clinicaltrials |
| NCT06234007 | Short-course Radiotherapy Followed by Fruquintinib Plus Adebrelimab and CAPOX in the Full Course Neoadjuvant Treatment of Locally Advanced Rectal Cancer: a Multicenter, Single-arm, Open-label Study | recruiting | Phase 2 | 45 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Mar 18, 2024 | clinicaltrials |
| NCT06314737 | Assessment of Efficacy of Neoadjuvant Therapy in Locally Advanced Rectal Cancer | completed | — | 3,515 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 0 | Mar 18, 2024 | clinicaltrials |
| NCT06311279 | End to End Versus Side to End Anastomosis After Anterior Resection of Cancer Rectum | unknown | N/A | 20 | Sohag UniversityOTHER | 1 | Mar 15, 2024 | clinicaltrials |
| NCT03951337 | 64Cu-ATSM PET/CT in Rectum Cancer (TEP 64Cu-ATSM-Rectum) | unknown | Phase 2 | 70 | Institut Cancerologie de l'OuestOTHER | 1 | Mar 12, 2024 | clinicaltrials |
| NCT06304545 | Treatment of Rectal Cancer With Long-term Concurrent Chemoradiotherapy Combined With Camrelizumab | not yet recruiting | Phase 2 | 48 | Harbin Medical UniversityOTHER | 0 | Mar 12, 2024 | clinicaltrials |
| NCT06304597 | Evaluating PD-1/PD-L1 in Locally Advanced Rectal Cancer by Quantitative Fluorescence Molecular Endoscopy(PREDICT) | unknown | Phase 1 | 18 | University Medical Center GroningenOTHER | 1 | Mar 12, 2024 | clinicaltrials |
| NCT06300489 | Genotype-driven Weekly Irinotecan Liposomes in Combination With Capecitabine-based Neoadjuvant Chemoradiation for Locally Advanced Rectal Cancer | unknown | Phase 1 | 30 | Zhejiang Cancer HospitalOTHER | 1 | Mar 8, 2024 | clinicaltrials |
| NCT05111860 | Neoadjuvant Bevacizumab + Chemotherapy Combined With Short-course Radiotherapy | unknown | Phase 1 / Phase 2 | 20 | Shanghai Minimally Invasive Surgery CenterOTHER | 1 | Mar 7, 2024 | clinicaltrials |
| NCT05933785 | the Value of Transanal Endoscopic ISR | completed | — | 260 | Shanghai Minimally Invasive Surgery CenterOTHER | 1 | Mar 7, 2024 | clinicaltrials |
| NCT06293612 | Constructing a Multimodal Imaging System to Predict the Risk of Heterochronous Metastasis of Rectal Cancer(MIS-MRC) | completed | — | 302 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 1 | Mar 5, 2024 | clinicaltrials |
| NCT00019006 | Vaccine Therapy in Treating Patients With Colon, Pancreatic, or Lung Cancer | completed | Phase 1 | — | National Cancer Institute (NCI)NIH | 1 | Mar 4, 2024 | clinicaltrials |
| NCT00020267 | Vaccine Therapy in Treating Patients With Metastatic Cancer | completed | Phase 1 | — | National Cancer Institute (NCI)NIH | 1 | Mar 4, 2024 | clinicaltrials |
| NCT00407654 | VEGF Trap in Treating Patients With Previously Treated Metastatic Colorectal Cancer | completed | Phase 2 | 75 | National Cancer Institute (NCI)NIH | 1 | Mar 4, 2024 | clinicaltrials |
| NCT06279299 | Lateral Pelvic Lymph Node Dissection for Rectal Neuroendocrine Neoplasms Undergoing Laparoscopic Total Mesenteric Excision | recruiting | N/A | 30 | National Cancer Center, ChinaOTHER | 1 | Feb 28, 2024 | clinicaltrials |
| NCT04923620 | Neoadjuvant Cetuximab + Chemotherapy Combined With Short-course Radiotherapy | unknown | — | 51 | Shanghai Minimally Invasive Surgery CenterOTHER | 1 | Feb 26, 2024 | clinicaltrials |
| NCT05498506 | Multiple Firings in Double-stapled Colorectal Anastomosis | completed | — | 350 | Shanghai Minimally Invasive Surgery CenterOTHER | 1 | Feb 26, 2024 | clinicaltrials |
| NCT05279287 | Video Analysis of Errors and Technical Performance Within Minimally Invasive Surgery Short Title: Video Analysis in Minimally Invasive Surgery (VAMIS)(VAMIS) | unknown | — | 100 | The Griffin InstituteOTHER | 1 | Feb 22, 2024 | clinicaltrials |
| NCT06266832 | The Efficacy and Safety of Short-course Radiation Combined With Adebrelimab and CAPEOX Neo-adjuvant Therapy for Organ-retention in Patients With MSS/pMMR Ultra Low Rectal Adenocarcinoma | recruiting | Phase 2 | 30 | Sir Run Run Shaw HospitalOTHER | 1 | Feb 20, 2024 | clinicaltrials |
| NCT05807646 | Reduced Dissemination of Tumor Cells With Primary Ligation of the Inferior Mesenteric Vein in Rectal Cancer Patients. | not yet recruiting | N/A | 268 | Sichuan Cancer Hospital and Research InstituteOTHER | 0 | Feb 15, 2024 | clinicaltrials |
| NCT04812743 | Colorectal Health Research Champions | terminated | N/A | 91 | Virginia Commonwealth UniversityOTHER | 1 | Feb 13, 2024 | clinicaltrials |
| NCT06254521 | The Effects of Neoadjuvant Tislelizumab Combined With Chemotherapy in Locally Advanced MSS Rectal Cancer | recruiting | Phase 2 | 60 | First Affiliated Hospital of Guangxi Medical UniversityOTHER | 1 | Feb 12, 2024 | clinicaltrials |
| NCT05980689 | Combination of AK104 and Neoadjuvant Chemoradiotherapy in pMMR/MSS Locally Advanced Rectal Cancer | unknown | Phase 2 | 33 | Sun Yat-sen UniversityOTHER | 1 | Feb 7, 2024 | clinicaltrials |
| NCT06244836 | Comparison of Two Bundles of Care to Reduce Surgical Site Infection in Colorectal Surgery (CCR-VINCat 2)(CCR-VINCat2) | completed | N/A | 32,205 | Hospital de GranollersOTHER | 1 | Feb 6, 2024 | clinicaltrials |
| NCT06239870 | Single-arm, Single-center, Exploratory Phase II Clinical Study of Envafolimab Combined With Chemoradiotherapy in the Treatment of Locally Advanced pMMR/MSS Rectal Cancer(ESTIMATE) | unknown | Phase 2 | 35 | Yunnan Cancer HospitalOTHER | 1 | Feb 2, 2024 | clinicaltrials |
Data updated 24 days agoSource updated May 1, 2024source: clinicaltrials