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Neoplasm by Special Category
CI-CAN-00000004Explore in graph →
Non-malignant21,340 active trials259 approved drugs3,859 evidence items
- NCIt
- C7062
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Other
CI-CAN-00000004Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
197 cases with simple somatic mutation data · 200 cases total · 2026-01-07 · mapped to Acute Myeloid Leukemia EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | FLT3 | Ssm |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| 56 |
| 197 |
| 28.4% |
| cbioportal |
| 2 | NPM1 | Ssm | 54 | 197 | 27.4% | cbioportal |
| 3 | DNMT3A | Ssm | 51 | 197 | 25.9% | cbioportal |
| 4 | IDH2 | Ssm | 20 | 197 | 10.2% | cbioportal |
| 5 | IDH1 | Ssm | 19 | 197 | 9.6% | cbioportal |
| 6 | RUNX1 | Ssm | 18 | 197 | 9.1% | cbioportal |
| 7 | TET2 | Ssm | 17 | 197 | 8.6% | cbioportal |
| 8 | TP53 | Ssm | 16 | 197 | 8.1% | cbioportal |
| 9 | NRAS | Ssm | 15 | 197 | 7.6% | cbioportal |
| 10 | CEBPA | Ssm | 13 | 197 | 6.6% | cbioportal |
| 11 | WT1 | Ssm | 12 | 197 | 6.1% | cbioportal |
| 12 | PTPN11 | Ssm | 9 | 197 | 4.6% | cbioportal |
| 14 | KRAS | Ssm | 8 | 197 | 4.1% | cbioportal |
| 13 | KIT | Ssm | 8 | 197 | 4.1% | cbioportal |
| 15 | U2AF1 | Ssm | 8 | 197 | 4.1% | cbioportal |
| 17 | SMC3 | Ssm | 7 | 197 | 3.6% | cbioportal |
| 16 | SMC1A | Ssm | 7 | 197 | 3.6% | cbioportal |
| 19 | STAG2 | Ssm | 6 | 197 | 3% | cbioportal |
| 18 | PHF6 | Ssm | 6 | 197 | 3% | cbioportal |
| 20 | TTN | Ssm | 6 | 197 | 3% | cbioportal |
| 22 | BRINP3 | Ssm | 5 | 197 | 2.5% | cbioportal |
| 21 | ASXL1 | Ssm | 5 | 197 | 2.5% | cbioportal |
| 23 | RAD21 | Ssm | 5 | 197 | 2.5% | cbioportal |
| 24 | PLCE1 | Ssm | 4 | 197 | 2% | cbioportal |
| 31 | DNAH9 | Ssm | 3 | 197 | 1.5% | cbioportal |
| 25 | CACNA1B | Ssm | 3 | 197 | 1.5% | cbioportal |
| 41 | SUZ12 | Ssm | 3 | 197 | 1.5% | cbioportal |
| 40 | SPEN | Ssm | 3 | 197 | 1.5% | cbioportal |
| 39 | SMG1 | Ssm | 3 | 197 | 1.5% | cbioportal |
| 38 | PTPRT | Ssm | 3 | 197 | 1.5% | cbioportal |
Data updated 22 days agoSource updated 2026-01-07