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Neoplasm by Special Category
CI-CAN-00000004Explore in graph →
Non-malignant21,340 active trials259 approved drugs3,859 evidence items
- NCIt
- C7062
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Other
CI-CAN-00000004Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
494 cases with simple somatic mutation data · 494 cases total · 2026-01-07 · mapped to Hepatocellular Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 255 |
| 494 |
| 51.6% |
| cbioportal |
| 3 | TTN | Ssm | 177 | 494 | 35.8% | cbioportal |
| 2 | TERT | Ssm | 177 | 494 | 35.8% | cbioportal |
| 4 | MUC16 | Ssm | 105 | 494 | 21.3% | cbioportal |
| 5 | CTNNB1 | Ssm | 102 | 494 | 20.6% | cbioportal |
| 6 | ALB | Ssm | 73 | 494 | 14.8% | cbioportal |
| 7 | PCLO | Ssm | 67 | 494 | 13.6% | cbioportal |
| 8 | CSMD3 | Ssm | 65 | 494 | 13.2% | cbioportal |
| 9 | SYNE1 | Ssm | 60 | 494 | 12.1% | cbioportal |
| 10 | LRP1B | Ssm | 59 | 494 | 11.9% | cbioportal |
| 11 | OBSCN | Ssm | 59 | 494 | 11.9% | cbioportal |
| 12 | HMCN1 | Ssm | 58 | 494 | 11.7% | cbioportal |
| 14 | RYR2 | Ssm | 57 | 494 | 11.5% | cbioportal |
| 13 | AXIN1 | Ssm | 57 | 494 | 11.5% | cbioportal |
| 15 | APOB | Ssm | 54 | 494 | 10.9% | cbioportal |
| 16 | ABCA13 | Ssm | 53 | 494 | 10.7% | cbioportal |
| 17 | PKHD1L1 | Ssm | 52 | 494 | 10.5% | cbioportal |
| 19 | FBN2 | Ssm | 51 | 494 | 10.3% | cbioportal |
| 18 | ARID1A | Ssm | 51 | 494 | 10.3% | cbioportal |
| 20 | FAT3 | Ssm | 50 | 494 | 10.1% | cbioportal |
| 22 | RYR3 | Ssm | 47 | 494 | 9.5% | cbioportal |
| 21 | ADGRV1 | Ssm | 47 | 494 | 9.5% | cbioportal |
| 24 | USH2A | Ssm | 43 | 494 | 8.7% | cbioportal |
| 23 | CSMD1 | Ssm | 43 | 494 | 8.7% | cbioportal |
| 25 | CSMD2 | Ssm | 41 | 494 | 8.3% | cbioportal |
| 26 | RYR1 | Ssm | 41 | 494 | 8.3% | cbioportal |
| 27 | XIRP2 | Ssm | 41 | 494 | 8.3% | cbioportal |
| 28 | SPTA1 | Ssm | 40 | 494 | 8.1% | cbioportal |
| 29 | MUC17 | Ssm | 39 | 494 | 7.9% | cbioportal |
| 31 | EYS | Ssm | 37 | 494 | 7.5% | cbioportal |
Data updated 22 days agoSource updated 2026-01-07