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Neoplasm by Special Category
CI-CAN-00000004Explore in graph →
Non-malignant21,340 active trials259 approved drugs3,859 evidence items
- NCIt
- C7062
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Other
CI-CAN-00000004Explore in graph →
Genomics
477 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
573 cases with simple somatic mutation data · 585 cases total · Data Release 46.0 · mapped to Lung Adenocarcinoma ONTOLOGY_EXACT
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | RYR2 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 413 |
| 573 |
| 72.1% |
| gdc |
| 2 | FLG | Ssm | 406 | 573 | 70.9% | gdc |
| 3 | USH2A | Ssm | 402 | 573 | 70.2% | gdc |
| 4 | SPTA1 | Ssm | 400 | 573 | 69.8% | gdc |
| 5 | TP53 | Ssm | 393 | 573 | 68.6% | gdc |
| 6 | FLG2 | Ssm | 388 | 573 | 67.7% | gdc |
| 8 | HRNR | Ssm | 383 | 573 | 66.8% | gdc |
| 7 | CSMD3 | Ssm | 383 | 573 | 66.8% | gdc |
| 11 | ASH1L | Ssm | 382 | 573 | 66.7% | gdc |
| 9 | TNR | Ssm | 382 | 573 | 66.7% | gdc |
| 10 | TNN | Ssm | 382 | 573 | 66.7% | gdc |
| 12 | HMCN1 | Ssm | 379 | 573 | 66.1% | gdc |
| 13 | MUC16 | Ssm | 376 | 573 | 65.6% | gdc |
| 15 | TCHH | Ssm | 374 | 573 | 65.3% | gdc |
| 14 | CACNA1E | Ssm | 374 | 573 | 65.3% | gdc |
| 16 | PAPPA2 | Ssm | 374 | 573 | 65.3% | gdc |
| 17 | ASTN1 | Ssm | 373 | 573 | 65.1% | gdc |
| 18 | KCNN3 | Ssm | 372 | 573 | 64.9% | gdc |
| 20 | ASPM | Ssm | 371 | 573 | 64.7% | gdc |
| 19 | NUP210L | Ssm | 371 | 573 | 64.7% | gdc |
| 22 | ADAR | Ssm | 370 | 573 | 64.6% | gdc |
| 23 | FCRL5 | Ssm | 370 | 573 | 64.6% | gdc |
| 21 | ATP8B2 | Ssm | 370 | 573 | 64.6% | gdc |
| 25 | AQP10 | Ssm | 369 | 573 | 64.4% | gdc |
| 24 | NPR1 | Ssm | 369 | 573 | 64.4% | gdc |
| 26 | PKLR | Ssm | 369 | 573 | 64.4% | gdc |
| 36 | BRINP3 | Ssm | 368 | 573 | 64.2% | gdc |
| 32 | CHRNB2 | Ssm | 368 | 573 | 64.2% | gdc |
| 37 | CHTOP | Ssm | 368 | 573 | 64.2% | gdc |
| 27 | CLK2 | Ssm | 368 | 573 | 64.2% | gdc |
Data updated 22 days agoSource updated Data Release 46.0