Cancer
Malignant Rectal Neoplasm
CI-CAN-00008012Explore in graph →
Top-level388 active trials1 approved drugs5 evidence items
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Cancer
CI-CAN-00008012Explore in graph →
Clinical trials
1,551 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (153)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT05078515 | Multicenter Validation of the PREDICT Score | completed | — | 262 | Mansoura UniversityOTHER | 1 | Oct 14, 2021 | clinicaltrials |
| NCT02665026 | Effectiveness and Safety Study on Different Timing of Preventive Ileostomy Closure After Surgery for Rectal Cancer | completed | N/A | 250 | Huashan HospitalOTHER | 1 | Sep 21, 2021 | clinicaltrials |
| Feasibility and Psychometric Properties of Paper vs. Web vs. Automated Telephone Administration of Patient Reported Outcome Surveys |
| completed |
| — |
| 325 |
| Memorial Sloan Kettering Cancer CenterOTHER |
| 1 |
| Sep 10, 2021 |
| clinicaltrials |
| NCT03107650 | Preoperative Prediction Model of Pathological Outcomes (Mesorectum Quality and Positive Circumferential Resection Margin) in Patients With Mid-low Rectal Cancer(PREMARE) | completed | — | 323 | Pere Planellas GinéOTHER | 1 | Sep 5, 2021 | clinicaltrials |
| NCT00040599 | Safety Study of 90Y-hMN14 to Treat Colorectal Cancer | completed | Phase 1 / Phase 2 | 72 | Gilead SciencesINDUSTRY | 5 | Aug 19, 2021 | clinicaltrials |
| NCT00041652 | Safety Study of hMN14 to Treat Either Colorectal or Breast Cancer | completed | Phase 1 / Phase 2 | 30 | Gilead SciencesINDUSTRY | 1 | Aug 19, 2021 | clinicaltrials |
| NCT01927497 | Biological Mesh Closure of the Pelvic Floor After Extralevator Abdomino Perineal Resection for Rectal Cancer(BIOPEX) | completed | Phase 3 | 104 | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)OTHER | 1 | Aug 17, 2021 | clinicaltrials |
| NCT02860234 | Tailored Operative or Non-operative Management for Low-risk Rectal Cancer After Intensive Neoadjuvant Treatment | completed | — | 68 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jul 23, 2021 | clinicaltrials |
| NCT02864849 | Total Neoadjuvant Induction and Consolidation CapeOX Plus IMRT With Capecitabine for MRI Defined High-risk Rectal Cancer | completed | Phase 2 | 81 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jul 23, 2021 | clinicaltrials |
| NCT02270606 | Phase I Study of Neoadjuvant Radiotherapy With 5-Fluorouracil for Rectal Cancer | completed | Phase 1 | 14 | Virginia Commonwealth UniversityOTHER | 1 | Jul 20, 2021 | clinicaltrials |
| NCT02393755 | Nintedanib and Capecitabine in Treating Patients With Refractory Metastatic Colorectal Cancer | completed | Phase 1 / Phase 2 | 42 | Roswell Park Cancer InstituteOTHER | 1 | Jul 8, 2021 | clinicaltrials |
| NCT04949672 | Pathology Assessment of Mesorectal Fascia After TME by Laparoscopic, Open, TransAnal and Robotic Approaches (LOTARTME)(LOTARTME) | completed | — | 153 | San Giovanni Addolorata HospitalOTHER | 1 | Jul 2, 2021 | clinicaltrials |
| NCT00695201 | Hepatic Arterial Infusion With Floxuridine and Dexamethasone in Combination With Intravenous Oxaliplatin Plus Irinotecan in Patients With Unresectable Hepatic Metastases From Colorectal Cancer | completed | Phase 1 | 52 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jul 1, 2021 | clinicaltrials |
| NCT01902953 | Lymphoseek® as Lymphoid Tissue Targeting Agents in Colon Cancer(CNC) | completed | Phase 2 | 16 | Maimonides Medical CenterOTHER | 1 | Jun 23, 2021 | clinicaltrials |
| NCT04896879 | Experiences and Needs of Patients, Their Informal Caregiver and Healthcare Professionals Regarding LARS | completed | — | 69 | University Hospital, GhentOTHER | 0 | May 21, 2021 | clinicaltrials |
| NCT01807117 | PET-MRI in Diagnosing Patients With Colon or Rectal Cancer | completed | N/A | 15 | Case Comprehensive Cancer CenterOTHER | 1 | May 18, 2021 | clinicaltrials |
| NCT04359498 | Retrospective Study of Surgical Complications in Patients With Defunctioning Stoma After Low Anterior Resection (LAR) | completed | — | 372 | SafehealINDUSTRY | 2 | May 10, 2021 | clinicaltrials |
| NCT00904813 | The Stockholm III Trial on Different Preoperative Radiotherapy Regimens in Rectal Cancer(Stockholm III) | completed | N/A | 840 | Karolinska InstitutetOTHER | 1 | May 7, 2021 | clinicaltrials |
| NCT04271657 | RadioPathomics Artificial Intelligence Model to Predict nCRT Response in Locally Advanced Rectal Cancer(RPAI-pCR) | completed | — | 100 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | May 6, 2021 | clinicaltrials |
| NCT02340949 | Induction FOLFOX With or Without Aflibercept Followed by Chemoradiation in High Risk Locally Advanced Rectal Cancer(RIA) | completed | Phase 2 | 180 | Grupo Espanol Multidisciplinario del Cancer DigestivoOTHER | 0 | May 3, 2021 | clinicaltrials |
| NCT04855448 | Evaluation of the Learning Curve in Low Anterior Resection for Rectal Resection With the Two Surgical Robots | completed | N/A | 112 | The Third Xiangya Hospital of Central South UniversityOTHER | 1 | Apr 22, 2021 | clinicaltrials |
| NCT03463616 | MRI Imaging or CT Abdomen as Standard Work-up Before Treatment Planning for Rectal Cancer? | completed | — | 320 | Sahlgrenska University HospitalOTHER | 1 | Apr 20, 2021 | clinicaltrials |
| NCT02217020 | Neoadjuvant FOLFOXIRI Chemotherapy Alone for Locally Advanced Rectal Cancer(FORTUNE) | completed | Phase 2 | 100 | Sun Yat-sen UniversityOTHER | 1 | Apr 14, 2021 | clinicaltrials |
| NCT01216189 | Sexual Function and Wellbeing in Females With Rectal Cancer | completed | — | 142 | Karolinska InstitutetOTHER | 1 | Apr 9, 2021 | clinicaltrials |
| NCT04697303 | Cross-sectional Study of Anorectal Function and Quality of Life in Patients With Middle and Low Rectal Cancer | completed | — | 600 | Quan WangOTHER | 1 | Apr 8, 2021 | clinicaltrials |
| NCT04836741 | Chinese Surgical Robot Clinical Study on Rectectomy for Rectal Cancer | completed | N/A | 105 | The Third Xiangya Hospital of Central South UniversityOTHER | 1 | Apr 8, 2021 | clinicaltrials |
| NCT04795180 | Pilot Randomized Evaluation of Butyrate Irrigation Before Ileostomy Closure on the Colonic Mucosa in Rectal Cancer Patients (BUTYCLO)(BUTYCLO) | completed | Phase 2 | 45 | Institut d'Investigació Biomèdica de Girona Dr. Josep TruetaOTHER | 1 | Mar 12, 2021 | clinicaltrials |
| NCT01037790 | Phase II Trial of the Cyclin-Dependent Kinase Inhibitor PD 0332991 in Patients With Cancer | completed | Phase 2 | 304 | Abramson Cancer Center at Penn MedicineOTHER | 1 | Mar 11, 2021 | clinicaltrials |
| NCT02112747 | Adherence to Colon Cancer Screening (ACCS) | completed | N/A | 1,900 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Mar 10, 2021 | clinicaltrials |
| NCT01985698 | A Trial of Robotic-assisted Versus Laparoscopic Abdominoperineal Resection for Treating Low Rectal Cancer(RLAPR) | completed | N/A | 347 | Fudan UniversityOTHER | 1 | Mar 9, 2021 | clinicaltrials |
| NCT01569672 | Ohio Patient Navigator Research Program(OPNRP) | completed | N/A | 941 | Ohio State University Comprehensive Cancer CenterOTHER | 1 | Feb 23, 2021 | clinicaltrials |
| NCT04761536 | Volume-outcome Relationship in Rectal Cancer Surgery | completed | — | 187 | University of Rome Tor VergataOTHER | 0 | Feb 21, 2021 | clinicaltrials |
| NCT02641691 | Non-Operative Radiation Management of Adenocarcinoma of the Lower Rectum(NORMAL-R) | completed | Phase 2 | 20 | Washington University School of MedicineOTHER | 1 | Feb 18, 2021 | clinicaltrials |
| NCT04591821 | Bowel Dysfunction 3 Years After Anterior Resection a in a Swedish National Cohort | completed | — | 1,200 | Region SkaneOTHER | 1 | Feb 18, 2021 | clinicaltrials |
| NCT04759638 | Short Running Head Obesity in Rectal Cancer Patients | completed | — | 294 | King Hussein Cancer CenterOTHER | 1 | Feb 18, 2021 | clinicaltrials |
| NCT04730102 | Rectal Washout in Transanal Total Mesorectal Excision and Presence of Intraluminal Malignant Cells | completed | — | 21 | Slagelse HospitalOTHER | 1 | Feb 10, 2021 | clinicaltrials |
| NCT04744792 | QoL of Colorectal Cancer Patients and Spouses | completed | — | 200 | Cihangir AkyolOTHER | 0 | Feb 9, 2021 | clinicaltrials |
| NCT01781403 | Preoperative CRT With Temozolomide Plus Capecitabine in Rectal Cancer | completed | Phase 1 | 22 | Asan Medical CenterOTHER | 1 | Feb 4, 2021 | clinicaltrials |
| NCT04738240 | Endoscopic Visualisation of Anastomosis in Colorectal Cancer Surgery(EVACCS) | completed | N/A | 18 | University of PlymouthOTHER | 1 | Feb 4, 2021 | clinicaltrials |
| NCT01481545 | Bevacizumab With Pelvic Radiotherapy And Primary Chemotherapy in Patients With Poor-Risk Rectal Cancer(BRANCH) | completed | Phase 2 | 62 | National Cancer Institute, NaplesOTHER | 0 | Feb 3, 2021 | clinicaltrials |
| NCT04733794 | Feasibility Bowel Dysfunction Program After Low Anterior Resection | completed | N/A | 14 | Fox Chase Cancer CenterOTHER | 1 | Feb 3, 2021 | clinicaltrials |
| NCT03443661 | Neoadjuvant Triplet Chemotherapy Regimen in Patients With Locally Advanced Rectal Cancer | completed | Phase 2 | 50 | Aiping ZhouUNKNOWN | 1 | Feb 1, 2021 | clinicaltrials |
| NCT01751516 | PET/MRI as a Predictor of Response to Pre-op Chemoradiation in Resectable Rectal Cancer: a Pilot Study | completed | — | 8 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | Jan 29, 2021 | clinicaltrials |
| NCT03881332 | Measurement of Perioperative Glomerular Filtration Rate | completed | — | 4 | University Hospital of North NorwayOTHER | 1 | Jan 26, 2021 | clinicaltrials |
| NCT01407107 | Dose Escalation Trial of Nitroglycerin, 5-flourouracil and Rad Therapy for Rectal Cancer | completed | Phase 1 | 13 | University of Texas Southwestern Medical CenterOTHER | 1 | Jan 14, 2021 | clinicaltrials |
| NCT01224392 | Simultaneous Integrated Boost Preoperative Radiotherapy for Rectum Cancer(RectumSIB) | completed | Phase 3 | 156 | Universitair Ziekenhuis BrusselOTHER | 1 | Dec 30, 2020 | clinicaltrials |
| NCT00807313 | Non-interventional Observational Study of Helical Tomotherapy for Oligometastatic Colorectal Cancer(tomoligo) | completed | — | 53 | Universitair Ziekenhuis BrusselOTHER | 1 | Dec 29, 2020 | clinicaltrials |
| NCT04683783 | National Registry of Liver First Approach(RENACI) | completed | — | 168 | Hospital Miguel ServetOTHER | 1 | Dec 24, 2020 | clinicaltrials |
| NCT04673526 | Laparoscopic Intersphincteric Resection in Elderly Patients | completed | N/A | 400 | ASL Verbano Cusio OssolaOTHER_GOV | 1 | Dec 22, 2020 | clinicaltrials |
| NCT04406311 | Italian Validation of the LARS Score | completed | — | 200 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Dec 14, 2020 | clinicaltrials |
Data updated 23 days agoSource updated Oct 14, 2021source: clinicaltrials