Clinical trial · Observational
Multicenter Validation of the PREDICT Score
Multicenter Validation of the PREDICT Score for Prediction of Local Recurrence After Total Mesorectal Excision of Rectal Cancer
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Even after adequate TME with grade III mesorectal grading, local recurrence remains a possible event. Several studies investigated different parameters and assessed their predictive power in regards to local recurrence after TME. These parameters included a variety of patient-related, tumor-related, and treatment-related factors. A recent meta-analysis reviewed the current literature for the predictors of local recurrence after TME for rectal cancer and developed a prognostic scoring system, the PREDICT score. The present study aimed to validate the PREDICT scoring system by applying it to a prospective cohort of patients with rectal cancer who underwent curative TME in three
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Rectal Cancer | Malignant Rectal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| PREDICT score | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- label
- Patients with recurrence after TME
- description
- Patients who developed local recurrence after TME of rectal cancer
- interventionNames
- Diagnostic Test: PREDICT score
- label
- Patients without recurrence after TME
- description
- Patients who did not develop local recurrence after TME of rectal cancer
- interventionNames
- Diagnostic Test: PREDICT score
Primary outcomes (2)
- measure
- Sensitivity of PREDICT score
- timeFrame
- 36 months after surgery
- description
- The ability of the score to predict actual cases of recurrence after TME
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Adult patients of either sex with non-metastatic low or middle rectal cancer who underwent elective TME with curative intent Exclusion Criteria: * Patients with recurrent or metastatic rectal cancer at the time of presentation * Patients with synchronous colon cancer * Patients with missing data on the outcome of TME.
References
Publications (0)
Data not yet available