Cancer Family
Malignant Musculoskeletal Neoplasm
CI-CAN-00000242Explore in graph →
141 active trials5 approved drugs46 evidence items
- NCIt
- C166357
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Cancer Family
CI-CAN-00000242Explore in graph →
Genomics
4 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
20 cases with simple somatic mutation data · 20 cases total · 2026-03-05 · mapped to Rhabdomyosarcoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | MYOD1 | Ssm | 20 | 20 | 100% | cbioportal |
| 2 | PIK3CA | Ssm | 5 | 20 | 25% | cbioportal |
| 3 | ARID1B | Ssm | 2 | 20 | 10% | cbioportal |
| 8 | NRAS | Ssm | 2 | 20 | 10% | cbioportal |
| 7 | NOTCH4 | Ssm | 2 | 20 | 10% | cbioportal |
| 6 | MAP3K1 | Ssm | 2 | 20 | 10% | cbioportal |
| 5 | FGFR4 | Ssm | 2 | 20 | 10% | cbioportal |
| 4 | CHEK2 |
Data updated 22 days agoSource updated 2026-03-05
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 2 |
| 20 |
| 10% |
| cbioportal |
| 9 | SMARCB1 | Ssm | 2 | 20 | 10% | cbioportal |
| 38 | ZFHX3 | Ssm | 1 | 17 | 5.9% | cbioportal |
| 21 | H3-3A | Ssm | 1 | 17 | 5.9% | cbioportal |
| 22 | H3C10 | Ssm | 1 | 17 | 5.9% | cbioportal |
| 23 | HLA-A | Ssm | 1 | 17 | 5.9% | cbioportal |
| 26 | INHBA | Ssm | 1 | 17 | 5.9% | cbioportal |
| 28 | MGA | Ssm | 1 | 17 | 5.9% | cbioportal |
| 31 | PLCG2 | Ssm | 1 | 17 | 5.9% | cbioportal |
| 36 | STAT5A | Ssm | 1 | 17 | 5.9% | cbioportal |
| 24 | IKBKE | Ssm | 1 | 20 | 5% | cbioportal |
| 25 | IL7R | Ssm | 1 | 20 | 5% | cbioportal |
| 35 | SPEN | Ssm | 1 | 20 | 5% | cbioportal |
| 27 | KMT2D | Ssm | 1 | 20 | 5% | cbioportal |
| 16 | CDKN2A | Ssm | 1 | 20 | 5% | cbioportal |
| 10 | ABL1 | Ssm | 1 | 20 | 5% | cbioportal |
| 15 | BCOR | Ssm | 1 | 20 | 5% | cbioportal |
| 29 | NOTCH1 | Ssm | 1 | 20 | 5% | cbioportal |
| 14 | ATM | Ssm | 1 | 20 | 5% | cbioportal |
| 13 | ARID5B | Ssm | 1 | 20 | 5% | cbioportal |
| 12 | ARID1A | Ssm | 1 | 20 | 5% | cbioportal |
| 30 | PIK3R3 | Ssm | 1 | 20 | 5% | cbioportal |
| 37 | TMEM127 | Ssm | 1 | 20 | 5% | cbioportal |