Cancer
Malignant Central Nervous System Neoplasm
CI-CAN-00001115Explore in graph →
Top-level822 active trials5 approved drugs103 evidence items
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Cancer
CI-CAN-00001115Explore in graph →
Clinical trials
2,864 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (418)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01063114 | Proton Beam Radiotherapy for Medulloblastoma and Pineoblastoma | completed | N/A | 90 | Massachusetts General HospitalOTHER | 1 | Aug 13, 2025 | clinicaltrials |
| NCT07119294 | Molecular Imaging of Cancer-associated Fibroblasts in Glioblastoma: a FAPI PET/MR Study.(GlioFAPI) | recruiting | N/A | 50 | Jules Bordet InstituteOTHER | 1 | Aug 13, 2025 | clinicaltrials |
| NCT05970757 | Physiological MRI for Precision Radiotherapy IDH-wildtype Glioblastoma(PhysMRRT) | active not recruiting | N/A | 10 | Erasmus Medical CenterOTHER | 1 | Aug 11, 2025 | clinicaltrials |
| NCT06617208 | Prognostic IntraOperative Biomarkers ideNtification in Tumor rElatEd suRgery(PIONEER) | not yet recruiting | N/A | 10 | Erasmus Medical CenterOTHER | 0 | Aug 8, 2025 | clinicaltrials |
| NCT07023640 | Application of the CD73-Targeted Probe ⁶⁸Ga-DOTA-mPNE PET/CT Imaging in the Diagnosis of Malignant Tumors | recruiting | N/A | 50 | Peking Union Medical College HospitalOTHER | 1 | Aug 5, 2025 | clinicaltrials |
| NCT05554159 | A Virtually Delivered Exercise Intervention To Mitigate Cognitive Deficits From Radiotherapy In AYAs With Brain Tumors | terminated | N/A | 10 | M.D. Anderson Cancer CenterOTHER | 1 | Aug 1, 2025 | clinicaltrials |
| NCT05383872 | Blood-Brain Barrier Disruption (BBBD) for Liquid Biopsy in Subjects With GlioBlastoma Brain Tumors | completed | N/A | 71 | InSightecINDUSTRY | 2 | Jul 28, 2025 | clinicaltrials |
| NCT07074470 | Combination Regimen of Teniposide, PD-1 Monoclonal Antibody and Selinixor for Patients With Relapsed or Refractory PCNSL(VPX) | recruiting | N/A | 40 | The First Affiliated Hospital of Soochow UniversityOTHER | 1 | Jul 20, 2025 | clinicaltrials |
| NCT04227717 | Studying a New Piece of Equipment That Can Help Plan Radiation Therapy of the Spine | completed | N/A | 9 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jul 18, 2025 | clinicaltrials |
| NCT06099743 | ASCENT Intervention for Brain Tumor Patients | recruiting | N/A | 100 | Massachusetts General HospitalOTHER | 1 | Jul 14, 2025 | clinicaltrials |
| NCT04266977 | Restrictive Use of Dexamethasone in Glioblastoma(RESDEX) | recruiting | N/A | 50 | Insel Gruppe AG, University Hospital BernOTHER | 1 | Jul 9, 2025 | clinicaltrials |
| NCT04838782 | Role of Repeat Resection in Recurrent Glioblastoma | withdrawn | N/A | 0 | University of AlbertaOTHER | 1 | Jul 8, 2025 | clinicaltrials |
| NCT07029100 | Feasibility of ORGAnoids in Routine Clinical Practice for Molecular Analysis of the GLIOvascular Niche in Patients With Primary Brain Tumors.(ORGA-GLIO) | not yet recruiting | N/A | 30 | Centre Henri BecquerelOTHER | 1 | Jun 19, 2025 | clinicaltrials |
| NCT04734444 | SonoClear Acoustic Coupling Fluid (ACF) Mimicking Brain Tissue | completed | N/A | 45 | SonoClear ASINDUSTRY | 3 | Jun 17, 2025 | clinicaltrials |
| NCT04610229 | Safety of IMRT Treatment With Inhomogeneous Dose in Patients With Relapsed High-grade Gliomas.(GLIORAD) | completed | N/A | 12 | Azienda USL Reggio Emilia - IRCCSOTHER_GOV | 1 | Jun 12, 2025 | clinicaltrials |
| NCT06183983 | Hitting the Mark: Introducing State-of-the-art MRI for Precision Radiotherapy of Glioblastoma(MOSAIC) | recruiting | N/A | 53 | Erasmus Medical CenterOTHER | 1 | Jun 12, 2025 | clinicaltrials |
| NCT06551909 | Radioimmunotherapy in Solid Tumors (PNRR-MCNT2-2023-12378239-Aim2) | recruiting | N/A | 30 | IRCCS San RaffaeleOTHER | 1 | Jun 8, 2025 | clinicaltrials |
| NCT05036564 | Diagnosis; Objective RespOnse; THErApy(DOROTHEA) | recruiting | N/A | 70 | IRCCS San RaffaeleOTHER | 1 | May 31, 2025 | clinicaltrials |
| NCT06499831 | 18F-FET-PET/MRI vs Standard MRI Alone for Stereotactic RadioTherapy Planning for High Grade Brain Gliomas(FETSMaRT) | unknown | N/A | 30 | Sunnybrook Health Sciences CentreOTHER | 1 | May 25, 2025 | clinicaltrials |
| NCT05927610 | Genetic Testing of Cerebrospinal Fluid to Diagnose and Monitor Glioblastoma | withdrawn | N/A | 0 | Memorial Sloan Kettering Cancer CenterOTHER | 0 | May 21, 2025 | clinicaltrials |
| NCT05474573 | Concurrent Fluorescence and Sonographically Guided Eradication of Contrast-enhancing Gliomas and Metastases(CONFLUENSE) | recruiting | N/A | 52 | Sklifosovsky Institute of Emergency CareOTHER_GOV | 1 | May 16, 2025 | clinicaltrials |
| NCT05485038 | General Anesthesia Versus Awake Surgery in Resection of Gliomas and Metastases of Motor Areas(GAMMA) | suspended | N/A | 72 | Sklifosovsky Institute of Emergency CareOTHER_GOV | 1 | May 16, 2025 | clinicaltrials |
| NCT06975332 | Local, Targeted Therapy With Alpha Emitter [225Ac]Ac-DOTA-SP (TAT) in Glioma (WHO G3-G4) Progression | recruiting | N/A | 35 | Medical University of WarsawOTHER | 1 | May 16, 2025 | clinicaltrials |
| NCT03593330 | Neurosurgical Transitional Care Programme(TCP) | terminated | N/A | 242 | Barts & The London NHS TrustOTHER | 1 | May 2, 2025 | clinicaltrials |
| NCT01473485 | ExAblate (Magnetic Resonance-guided Focused Ultrasound Surgery) Treatment of Brain Tumors | active not recruiting | N/A | 10 | InSightecINDUSTRY | 1 | May 1, 2025 | clinicaltrials |
| NCT06869577 | A Supportive Group Intervention for Caregivers to Patients Diagnosed With a Glioblastoma(SUGRI) | not yet recruiting | N/A | 24 | Rigshospitalet, DenmarkOTHER | 1 | Apr 29, 2025 | clinicaltrials |
| NCT06946407 | Rituximab, Methotrexate, and Tepadina Induction Followed by Etoposide and Cytarabine Consolidation in Primary Central Nervous System Lymphoma | recruiting | N/A | 41 | FengYan JinOTHER | 1 | Apr 27, 2025 | clinicaltrials |
| NCT06929819 | Research on the Safety and Efficacy of Intraoperative Radiation Therapy in Malignant Cerebral Tumor | not yet recruiting | N/A | 200 | First Affiliated Hospital, Sun Yat-Sen UniversityOTHER | 0 | Apr 16, 2025 | clinicaltrials |
| NCT04474964 | Focal Radiotherapy Plus Low Dose Craniospinal Irradiation Followed by Adjuvant Chemotherapy in WNT Medulloblastoma.(FOR-WNT2) | recruiting | N/A | 30 | Tata Memorial CentreOTHER | 1 | Apr 9, 2025 | clinicaltrials |
| NCT01604512 | A Comparison of MRI Perfusion and FDG PET/CT to Distinguish Between Radiation Injury and Tumor Progression | completed | N/A | 148 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Apr 8, 2025 | clinicaltrials |
| NCT05746754 | Proton Cranio-spinal Irradiation for Leptomeningeal Metastasis(CSI ProLong) | recruiting | N/A | 50 | University of AarhusOTHER | 1 | Apr 6, 2025 | clinicaltrials |
| NCT05753995 | Immuno-Positron Emission Tomography (PET)-Glioma Study, a Proof-of-principle Imaging Study | active not recruiting | N/A | 20 | Kepler University HospitalOTHER | 1 | Apr 1, 2025 | clinicaltrials |
| NCT05759195 | Biomolecular Analysis for Predicting Response to Regorafenib(RegoRec) | completed | N/A | 53 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Mar 13, 2025 | clinicaltrials |
| NCT05772767 | Modulation of Ciliogenesis in Glioma Stem Cells(RF2019-1236878) | completed | N/A | 100 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Mar 13, 2025 | clinicaltrials |
| NCT05793034 | Predictive Factors for Survival in Aggressive Meningiomas(23Men) | recruiting | N/A | 250 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Mar 13, 2025 | clinicaltrials |
| NCT05941234 | Stem Cell Analysis, Omics (Including Immunomics) and Artificial Intelligence in Glioblastoma(IPerGlioGEM) | recruiting | N/A | 120 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Mar 13, 2025 | clinicaltrials |
| NCT06781372 | Patient's Derived Organoids for Drug Screening in Glioblastoma(GlioPDO) | not yet recruiting | N/A | 100 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Mar 13, 2025 | clinicaltrials |
| NCT06643000 | Evaluating High-dose Furmonertinib with Bevacizumab and Pemetrexed for EGFRm NSCLC with Leptomeningeal Metastasis | recruiting | N/A | 60 | Henan Cancer HospitalOTHER_GOV | 1 | Mar 6, 2025 | clinicaltrials |
| NCT05131815 | The BurnAlong Pilot Study for Adolescent and Young Adult Cancer Survivors | completed | N/A | 8 | Cedars-Sinai Medical CenterOTHER | 1 | Feb 26, 2025 | clinicaltrials |
| NCT04903678 | Intrathecal Chemotherapy for Central Nervous System Metastasis in Retinoblastoma | recruiting | N/A | 18 | Eye & ENT Hospital of Fudan UniversityOTHER | 1 | Feb 25, 2025 | clinicaltrials |
| NCT06832267 | Rituximab-Methotrexate-Temozolomide-Thiotepa (RMTT) Regimen As First-line Therapy for PCNS DLBCL | recruiting | N/A | 44 | Zhejiang Cancer HospitalOTHER | 1 | Feb 18, 2025 | clinicaltrials |
| NCT03181477 | Study Evaluating the Efficacy of Radiotherapy With SIB-IMRT, Associated With Temozolomide in Glioblastomas(Glio-SIB-Up) | active not recruiting | N/A | 67 | Centre Georges Francois LeclercOTHER | 1 | Feb 17, 2025 | clinicaltrials |
| NCT05140902 | Accurate DCE-MRI Measurement of Glioblastoma Using Point-of-care Portable Perfusion Phantom | completed | N/A | 12 | University of Alabama at BirminghamOTHER | 1 | Feb 14, 2025 | clinicaltrials |
| NCT04047602 | Radiosurgery Dose Reduction for Brain Metastases on Immunotherapy (RADREMI): A Prospective Pilot Study(RADREMI) | terminated | N/A | 18 | Indiana UniversityOTHER | 1 | Feb 13, 2025 | clinicaltrials |
| NCT06140875 | Amplitude Modulated Radiofrequency Electromagnetic Field Treatment Combined With Radiochemotherapy and Maintenance Chemotherapy in Patients With Glioblastoma (Brain-RF) | recruiting | N/A | 26 | Charite University, Berlin, GermanyOTHER | 1 | Feb 13, 2025 | clinicaltrials |
| NCT04962672 | Anesthesia Induced Brain Cancer Survival (ABC Survival): A Feasibility Study | recruiting | N/A | 40 | University Health Network, TorontoOTHER | 1 | Jan 31, 2025 | clinicaltrials |
| NCT06113705 | Imaging and Biological Markers for Prediction and Identification of Glioblastoma Pseudoprogression: a Prospective Study. | recruiting | N/A | 75 | Istituto Clinico HumanitasOTHER | 1 | Jan 31, 2025 | clinicaltrials |
| NCT05911230 | Advanced Diffusion MRI to Differentiate Tumor Recurrence From Pseudoprogression in Patients With Glioblastoma and Brain Metastases(AiD-GLIO) | recruiting | N/A | 10 | University Hospital, Basel, SwitzerlandOTHER | 1 | Jan 29, 2025 | clinicaltrials |
| NCT03154190 | Health Care Coach Support in Reducing Acute Care Use and Cost in Patients With Cancer | completed | N/A | 128 | Stanford UniversityOTHER | 1 | Jan 24, 2025 | clinicaltrials |
| NCT03717142 | Feasibility of the LUM Imaging System for Detection of Cancer to the Brain | terminated | N/A | 4 | Lumicell, Inc.INDUSTRY | 1 | Jan 15, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Aug 13, 2025source: clinicaltrials