Cancer
Malignant Central Nervous System Neoplasm
CI-CAN-00001115Explore in graph →
Top-level823 active trials5 approved drugs103 evidence items
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Cancer
CI-CAN-00001115Explore in graph →
Clinical trials
2,864 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (419)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT03975829 | Pediatric Long-Term Follow-up and Rollover Study | active not recruiting | Phase 4 | 163 | Novartis PharmaceuticalsINDUSTRY | 19 | Aug 27, 2026 | clinicaltrials |
| NCT02875314 | HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors | active not recruiting | Phase 4 | 250 | Parth PatelOTHER | 3 | Jun 3, 2026 | clinicaltrials |
| NCT06625047 |
| Comparing Telehealth and In-person Assessments in Glioma Patients Receiving Oral Chemotherapy |
| completed |
| Phase 4 |
| 30 |
| Mayo ClinicOTHER |
| 1 |
| Apr 29, 2026 |
| clinicaltrials |
| NCT07546669 | Efficacy of Zoster Vaccination in Glioblastoma Patients(STARGATE) | not yet recruiting | Phase 4 | 230 | University Hospital, EssenOTHER | 0 | Apr 23, 2026 | clinicaltrials |
| NCT04081701 | 68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors.(DOMINO-START) | recruiting | Phase 4 | 200 | Weill Medical College of Cornell UniversityOTHER | 1 | Nov 21, 2025 | clinicaltrials |
| NCT05342883 | GammaTile and Stupp in Newly Diagnosed GBM(GESTALT) | active not recruiting | Phase 4 | 61 | GT Medical Technologies, Inc.INDUSTRY | 1 | Sep 5, 2025 | clinicaltrials |
| NCT07092202 | Firmonertinib Combined With Intrathecal Injection for the Treatment of EGFR Mutant NSCLC With Leptomeningeal Metastases | recruiting | Phase 4 | 40 | Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologyOTHER | 1 | Jul 29, 2025 | clinicaltrials |
| NCT05900908 | Post-operative Adjuvant Therapy w/wo GammaTile + Systemic Therapy(PATHWAyS) | withdrawn | Phase 4 | 0 | GT Medical Technologies, Inc.INDUSTRY | 0 | Apr 10, 2025 | clinicaltrials |
| NCT05235737 | The Assessment of Immune Response in Newly Diagnosed Glioblastoma Patients Treated With Pembrolizumab(PIRG) | unknown | Phase 4 | 36 | Medical University of SilesiaOTHER | 1 | Aug 31, 2023 | clinicaltrials |
| NCT04650204 | Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy | terminated | Phase 4 | 4 | Mayo ClinicOTHER | 1 | Jun 22, 2023 | clinicaltrials |
| NCT05518383 | B-cell Mature Non-Hodgkin's Lymphoma Treatment Protocol in Children and Adolescents 2021 | recruiting | Phase 4 | 300 | Federal Research Institute of Pediatric Hematology, Oncology and ImmunologyOTHER | 1 | Aug 26, 2022 | clinicaltrials |
| NCT02334722 | 1 Week Versus 6 Weeks of Levetiracetam in Surgical Brain Tumor Patients | completed | Phase 4 | 81 | University of FloridaOTHER | 1 | Dec 15, 2021 | clinicaltrials |
| NCT04356118 | Efficacy and Safety of Recombinant Human Endostatin in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis | unknown | Phase 4 | 30 | Hui BuOTHER | 0 | May 27, 2020 | clinicaltrials |
| NCT04356222 | Efficacy and Safety of Durvalumab in Non-Small Cell Lung Cancer With Leptomeningeal Metastasis | unknown | Phase 4 | 30 | Hui BuOTHER | 0 | May 27, 2020 | clinicaltrials |
| NCT04083066 | Open Randomized Prospective Clinical Study of R-FPD Versus R-MAD Regimen in the Treatment of Primary Central Nervous System Lymphoma | unknown | Phase 4 | 20 | Mingzhi ZhangOTHER | 1 | Sep 10, 2019 | clinicaltrials |
| NCT02933333 | G-CSF Alone or Combination With GM-CSF on Prevention and Treatment of Infection in Children With Malignant Tumor | unknown | Phase 4 | 405 | Xinhua Hospital, Shanghai Jiao Tong University School of MedicineOTHER | 1 | Oct 17, 2018 | clinicaltrials |
| NCT00686725 | Standard Temodal (Temozolomide) Regimen Versus Standard Regimen Plus Early Postsurgery Temodal for Newly Diagnosed Glioblastoma Multiforme (Study P05572) | completed | Phase 4 | 99 | Merck Sharp & Dohme LLCINDUSTRY | 0 | Jun 14, 2017 | clinicaltrials |
| NCT02590510 | Different Dose of Methotrexate for the Treatment of Meningeal Carcinomatosis | unknown | Phase 4 | 50 | Hui BuOTHER | 0 | Oct 28, 2016 | clinicaltrials |
| NCT02708056 | Sugammadex Given for the Reversal of Rocuronium Induced Neuromuscular Blockade Under Sevoflurane Anesthesia in Infants | completed | Phase 4 | 26 | Baskent UniversityOTHER | 0 | Mar 15, 2016 | clinicaltrials |
| NCT01756729 | Post-approval Study of NovoTTF-100A in Recurrent GBM Patients | terminated | Phase 4 | 13 | NovoCure Ltd.INDUSTRY | 1 | Mar 2, 2016 | clinicaltrials |
| NCT01960192 | Treatment of Primary CNS Lymphoma(FVD) | unknown | Phase 4 | 50 | Mingzhi ZhangOTHER | 1 | Jul 21, 2015 | clinicaltrials |
| NCT02319486 | CEV With/Without Periocular Carboplatin Chemotherapy for Extraocular Retinoblastoma | completed | Phase 4 | 26 | Sun Yat-sen UniversityOTHER | 0 | Mar 30, 2015 | clinicaltrials |
| NCT00153530 | Whole Brain Irradiation in Primary Central Nervous System (CNS) Lymphoma (PCNSL) | completed | Phase 4 | 604 | Charite University, Berlin, GermanyOTHER | 1 | Dec 24, 2009 | clinicaltrials |
| NCT00336531 | Efficacy of Prophylactic Itraconazole in High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantation | completed | Phase 4 | 100 | Samsung Medical CenterOTHER | 1 | Nov 19, 2008 | clinicaltrials |
Data updated 22 days agoSource updated Aug 27, 2026source: clinicaltrials