Clinical trial · Interventional
Studying a New Piece of Equipment That Can Help Plan Radiation Therapy of the Spine
Assessment of a Custom-Built MRI Coil for Spine Radiotherapy Treatment Planning
NCT04227717CI-TRIAL-00092325completedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
Participants will receive an MRI with a custom-built MRI coil for each participant. The purpose is to find out whether this custom-built MRI coil can help doctors see the different parts of the spine as well as or better than they can with standard CT myelograms.
Conditions
Conditions (6)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Spine Cancer | Malignant Spinal Cord Neoplasm | ALIAS | 0.90 |
| Spine Disease | — | UNRESOLVED | — |
| Spine Metastases | — | UNRESOLVED | — |
| Thoracic Cancer | Malignant Thoracic Neoplasm | ALIAS | 0.90 |
| Thoracic Diseases | — | UNRESOLVED | — |
| Thoracic Neoplasms | Thoracic Neoplasm | ONTOLOGY_EXACT | 0.98 |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| MRI with custom MRI spine coil | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- EXPERIMENTAL
- label
- Thoracic, lumbar and sacral spine lesions
- description
- Participants will have thoracic, lumbar and sacral spine lesions
- interventionNames
- Diagnostic Test: MRI with custom MRI spine coil
Primary outcomes (1)
- measure
- Difference of calculated doses to the cauda equine and spinal cord based upon MRI coil vs CT myelogram used to define each structure
- timeFrame
- 6 months
- description
- The calculated doses to the cauda equine and spinal cord will be compared and evaluated for significant difference based upon the imaging modality (MRI coil vs CT myelogram) used to define each structure, with all other target and avoidance volumes being equal in the same patient.
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * \>/= 18 years of age at the time of treatment * Able to give informed consent * Consented for spine stereotactic radiation therapy * No contraindications for CT myelograms which include: * Allergy to CT contrast * Use of phenothiazines * Platelet count \< 60,000 K/mcl * INR \> 1.5 * VEGF inhibitor use in the past 2 weeks prior to myelogram * NSAID use in the past 5 days prior to myelogram * Renal disease * Creatinine \> 1.2 mg/dL * No contraindications for MRI scans which include: * Newly placed glucose monitors * Tattoos (Tattoos for radiation therapy are allowed) * Presence of a cardiac pacemaker * Presence of an implanted cardioverter defibrillator * Breast tissue expander * Aneurysm clip * Any other implanted metallic (BB, bullet, shrapnel, IUD, metallic stent or filter, spinal cord simulator etc.) or electronic device which is considered MR unsafe * Severe claustrophobia or inability to lie flat for the duration of the study, etc. Exclusion Criteria: * Presence of surgical spine hardware at the region of interest * Presence of cervical spine lesions * History of claustrophobia
References
Publications (0)
Data not yet available
No reference posted for this study.