Clinical trial · Interventional
Predictive Factors for Survival in Aggressive Meningiomas
Analysis of Predictive Factors for Overall and Progression-free Survival After Neurosurgery for Atypical or Anaplastic Meningioma
NCT05793034CI-TRIAL-0008715223MenrecruitingN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
The investigators plan to collect clinical and molecular data, including ICH, PCR, NGS and methylome, from patients operated on for grade 2 or grade 3 meningioma. The purpose of the study is to identify reliable and easy-to-assess predictive factors for recurrence and survival after surgery.
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Anaplastic Meningioma | Anaplastic (Malignant) Meningioma | ALIAS | 0.90 |
| Meningioma | Meningioma | ONTOLOGY_EXACT | 0.90 |
| Meningioma Atypical | — | UNRESOLVED | — |
Interventions
Interventions (1)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Biological biomarker assessment | Diagnostic Test | — | UNRESOLVED |
Design
Arms and outcomes
Arms (1)
- type
- OTHER
- label
- Biological biomarker assessment
- description
- FFPE tumor tissue will be processed with a number of molecular biology techniques
- interventionNames
- Diagnostic Test: Biological biomarker assessment
Primary outcomes (1)
- measure
- Recurrence-free survival (RFS)
- timeFrame
- 5 years on average
- description
- Correlation from biomolecular data and RFS
Secondary outcomes (1)
- measure
- Overall survival (OS)
- timeFrame
- 5 years on average
- description
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: 1. Patient operated for atypical (grade 2) meningioma; or 2. Patient operated for anaplastic (grade 3) meningioma; 3. Timeframe for surgery, 1999-2019 Exclusion criteria 1\) Patient lost at follow-up
References
Publications (0)
Data not yet available
No reference posted for this study.