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Lung Neuroendocrine Carcinoma · CancerIndex

Cancers
Neoplasm
Neoplasm by Site
Endocrine Neoplasm
Neuroendocrine Neoplasm
Lung Neuroendocrine Neoplasm
Lung Neuroendocrine Carcinoma

Subtype

Lung Neuroendocrine Carcinoma

CI-CAN-00003107Explore in graph →

389 active trials6 approved drugs6 evidence items

NCIt: C45569

Overview
Statistics
Survival
Genomics4
Variants & evidence6
Drugs8
Trials1113
Research
Rankings
Sources & provenance

Data completeness5 / 7 dimensions

Epidemiology (no data yet)
Survival (no data yet)
Trials (data present)
Literature (data present)
Genomics (data present)
Evidence (data present)
Therapies (data present)

Computed from entity_counters.completeness · refreshed after each connector run

Definition

What this entity is

An aggressive high-grade carcinoma with neuroendocrine differentiation that arises from the lung. It is classified as small cell lung carcinoma, large cell lung neuroendocrine carcinoma, or combined lung carcinoma.

Definition text as published by ncit-evsProvenance

Source: NCI Thesaurus (NCIt)
Dataset: NCI Thesaurus
Version: 26.08e
Retrieved: Sep 8, 2026
Layer: raw (as published)
Evidence: expert curation
License: CC BY 4.0
Run: ING-NCITEVS-20260908-000001

Open at source Curated

Data updated 22 days agoSource updated 26.08e

Taxonomy

Position in the hierarchies

Several hierarchies coexist; edges are listed per hierarchy type with their source.

Parents

ncit

Lung CarcinomaSubtype
Lung Neuroendocrine NeoplasmSubtype
Neuroendocrine CarcinomaSubtype

Children (3)

ncit

Combined Lung Carcinoma2 sub
Lung Large Cell Neuroendocrine Carcinoma1 sub
Lung Small Cell Carcinoma7 sub

20 descendants in total; counters on this page aggregate over all of them.

Anatomy

Anatomical sites

EndocrineC3010
Respiratory SystemC3355
ThoracicC3406

Record

Identity

CancerIndex ID: CI-CAN-00003107
Entity type: Subtype
Malignant: Yes
Solid / hematologic: Solid tumor
Pediatric relevant: Not flagged
Rare cancer: Unknown (no incidence data yet)
Hierarchy depth: 5
Classification version: 26.08e
Semantic types: Neoplastic Process
Status: Active
Record updated: 2026-09-08

Coverage

Data completeness

Trials (all / active)

1,113 / 389

Publications (all / 5y)

41 / 22

Evidence items

6

Genes / variants

44 / 6

Drugs (any / approved)

8 / 6

Genomic cohorts

4

Epidemiology / survival obs.

0 / 0

Data updated 14 minutes agoSource updated unknowncounters aggregate over descendants

Names

Synonyms (1)

High Grade Lung Neuroendocrine Neoplasmsynonym · NCIt

CancerIndex is a research and information platform. It does not diagnose and does not recommend treatment.

Key figures

At a glance

Each figure carries its unit, period and source; ranks link to "Why this rank?".

US deaths128,762countUnited States · 2024 · both sexes · all agescdc-wonderObservedrank #1 of 31 (USA · both sexes · all ages · 2024 · top-level cancers)figures shown for Malignant Lung Neoplasm (registry level) — open Malignant Lung Neoplasm
US new cases228,058countUnited States · 2023 · both sexes · all agescdc-uscsObservedrank #3 of 32 (USA · both sexes · all ages · 2023 · top-level cancers)figures shown for Malignant Lung Neoplasm (registry level) — open Malignant Lung Neoplasm
US age-standardized mortality28per 100,000United States · 2024 · both sexes · all ages · 2000 U.S. Std. Populationcdc-wonderObservedrank #1 of 23 (USA · both sexes · all ages · 2024 · top-level cancers)figures shown for Malignant Lung Neoplasm (registry level) — open Malignant Lung Neoplasm
Active trials389countcurrent registry status · entity + descendantsclinicaltrialsComputedrank #97 of 1,654 (World · both sexes · all ages · latest · all malignant entities)
Recruiting trials206countstatus RECRUITING · entity + descendantsclinicaltrialsComputedrank #101 of 1,284 (World · both sexes · all ages · latest · all malignant entities)
Curated evidence items6countaccepted CIViC items · entity + descendantscivicComputedrank #239 of 492 (World · both sexes · all ages · latest · all malignant entities)
Publications, last 12 months4countPubMed records · stored query · 12-month windowpubmedComputedrank #1352 of 2,294 (World · both sexes · all ages · latest · all malignant entities)
Genomic cohorts4countopen GDC projects · entity + descendantsgdcComputedrank #172 of 296 (World · both sexes · all ages · latest · all malignant entities)

Data updated 14 minutes agoSource updated unknownregistry figures: cdc-uscs · latest year available per metric · counters aggregate over descendants