Cancer Family
Invasive Malignant Neoplasm
CI-CAN-00000213Explore in graph →
604 active trials9 approved drugs37 evidence items
- NCIt
- C8505
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Cancer Family
CI-CAN-00000213Explore in graph →
Genomics
65 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
100 cases with simple somatic mutation data · 100 cases total · 2026-01-05 · mapped to Invasive Breast Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 37 |
| 100 |
| 37% |
| cbioportal |
| 2 | PIK3CA | Ssm | 30 | 100 | 30% | cbioportal |
| 3 | TTN | Ssm | 26 | 100 | 26% | cbioportal |
| 4 | GATA3 | Ssm | 15 | 100 | 15% | cbioportal |
| 5 | KMT2C | Ssm | 11 | 100 | 11% | cbioportal |
| 6 | MUC16 | Ssm | 10 | 100 | 10% | cbioportal |
| 7 | CDH1 | Ssm | 8 | 100 | 8% | cbioportal |
| 8 | BIRC6 | Ssm | 7 | 100 | 7% | cbioportal |
| 9 | FSIP2 | Ssm | 7 | 100 | 7% | cbioportal |
| 10 | SYNE1 | Ssm | 7 | 100 | 7% | cbioportal |
| 11 | CSMD1 | Ssm | 6 | 100 | 6% | cbioportal |
| 15 | NCOR1 | Ssm | 6 | 100 | 6% | cbioportal |
| 14 | MAP3K1 | Ssm | 6 | 100 | 6% | cbioportal |
| 12 | DNAH11 | Ssm | 6 | 100 | 6% | cbioportal |
| 16 | STAB2 | Ssm | 6 | 100 | 6% | cbioportal |
| 13 | DST | Ssm | 6 | 100 | 6% | cbioportal |
| 17 | VPS13C | Ssm | 6 | 100 | 6% | cbioportal |
| 18 | ADGRG4 | Ssm | 5 | 100 | 5% | cbioportal |
| 19 | AKT1 | Ssm | 5 | 100 | 5% | cbioportal |
| 25 | LRP2 | Ssm | 5 | 100 | 5% | cbioportal |
| 26 | MAP2K4 | Ssm | 5 | 100 | 5% | cbioportal |
| 28 | PRRC2B | Ssm | 5 | 100 | 5% | cbioportal |
| 22 | DIDO1 | Ssm | 5 | 100 | 5% | cbioportal |
| 20 | ARID1B | Ssm | 5 | 100 | 5% | cbioportal |
| 27 | NBAS | Ssm | 5 | 100 | 5% | cbioportal |
| 29 | TENM1 | Ssm | 5 | 100 | 5% | cbioportal |
| 21 | BRCA2 | Ssm | 5 | 100 | 5% | cbioportal |
| 24 | HYDIN2 | Ssm | 5 | 100 | 5% | cbioportal |
| 23 | HERC1 | Ssm | 5 | 100 | 5% | cbioportal |
| 34 | CIT | Ssm | 4 | 100 | 4% | cbioportal |
Data updated 22 days agoSource updated 2026-01-05