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Invasive Malignant Neoplasm · CancerIndex

Cancers
Neoplasm
Neoplasm by Special Category
Malignant Neoplasm
Invasive Malignant Neoplasm

Cancer Family

Invasive Malignant Neoplasm

CI-CAN-00000213Explore in graph →

604 active trials9 approved drugs37 evidence items

NCIt: C8505

Overview
Statistics
Survival
Genomics65
Variants & evidence37
Drugs22
Trials1820
Research
Rankings
Sources & provenance

Data completeness5 / 7 dimensions

Epidemiology (no data yet)
Survival (no data yet)
Trials (data present)
Literature (data present)
Genomics (data present)
Evidence (data present)
Therapies (data present)

Computed from entity_counters.completeness · refreshed after each connector run

Definition

What this entity is

A malignant neoplasm that has spread beyond the layer of tissue in which it developed and is growing into surrounding, healthy tissues.

Definition text as published by ncit-evsProvenance

Source: NCI Thesaurus (NCIt)
Dataset: NCI Thesaurus
Version: 26.08e
Retrieved: Sep 8, 2026
Layer: raw (as published)
Evidence: expert curation
License: CC BY 4.0
Run: ING-NCITEVS-20260908-000001

Open at source Curated

Data updated 22 days agoSource updated 26.08e

Taxonomy

Position in the hierarchies

Several hierarchies coexist; edges are listed per hierarchy type with their source.

Parents

ncit

Malignant NeoplasmCancer Family

Children (4)

ncit

Invasive Carcinoma16 sub
Invasive Cutaneous Melanoma
Invasive Malignant Thymoma
Microinvasive Malignant Neoplasm4 sub

259 descendants in total; counters on this page aggregate over all of them.

Anatomy

Anatomical sites

Data not yet available

No anatomical site linked yet.

Record

Identity

CancerIndex ID: CI-CAN-00000213
Entity type: Cancer Family
Malignant: Yes
Solid / hematologic: Solid tumor
Pediatric relevant: Not flagged
Rare cancer: Unknown (no incidence data yet)
Hierarchy depth: 3
Classification version: 26.08e
Semantic types: Neoplastic Process
Status: Active
Record updated: 2026-09-08

Coverage

Data completeness

Trials (all / active)

1,820 / 604

Publications (all / 5y)

7,632 / 1,770

Evidence items

37

Genes / variants

496 / 27

Drugs (any / approved)

22 / 9

Genomic cohorts

65

Epidemiology / survival obs.

0 / 0

Data updated 18 hours agoSource updated unknowncounters aggregate over descendants

Names

Synonyms (3)

infiltrating cancersynonym · NCIt
Infiltrating Malignant Neoplasmsynonym · NCIt
Invasive Cancersynonym · NCIt

CancerIndex is a research and information platform. It does not diagnose and does not recommend treatment.

Key figures

At a glance

Each figure carries its unit, period and source; ranks link to "Why this rank?".

No registry-level ancestor: burden figures are published for the mutually exclusive top-level site groups only, and this entity does not descend from one. Global figures (IARC / GLOBOCAN) stay under license review and SEER awaits credentials.

Active trials604countcurrent registry status · entity + descendantsclinicaltrialsComputedrank #62 of 1,654 (World · both sexes · all ages · latest · all malignant entities)
Recruiting trials302countstatus RECRUITING · entity + descendantsclinicaltrialsComputedrank #67 of 1,277 (World · both sexes · all ages · latest · all malignant entities)
Curated evidence items37countaccepted CIViC items · entity + descendantscivicComputedrank #97 of 492 (World · both sexes · all ages · latest · all malignant entities)
Publications, last 12 months369countPubMed records · stored query · 12-month windowpubmedComputedrank #178 of 2,294 (World · both sexes · all ages · latest · all malignant entities)
Genomic cohorts65countopen GDC projects · entity + descendantsgdcComputedrank #12 of 296 (World · both sexes · all ages · latest · all malignant entities)

Data updated 18 hours agoSource updated unknownregistry figures: none · counters aggregate over descendants