Cancer Family
Invasive Malignant Neoplasm
CI-CAN-00000213Explore in graph →
604 active trials9 approved drugs37 evidence items
- NCIt
- C8505
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Cancer Family
CI-CAN-00000213Explore in graph →
Genomics
65 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
75 cases with simple somatic mutation data · 75 cases total · 2026-01-05 · mapped to Invasive Breast Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | TP53 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 53 |
| 75 |
| 70.7% |
| cbioportal |
| 2 | TTN | Ssm | 19 | 75 | 25.3% | cbioportal |
| 3 | MUC16 | Ssm | 14 | 75 | 18.7% | cbioportal |
| 5 | OBSCN | Ssm | 13 | 75 | 17.3% | cbioportal |
| 4 | DNAH8 | Ssm | 13 | 75 | 17.3% | cbioportal |
| 6 | FLG | Ssm | 12 | 75 | 16% | cbioportal |
| 7 | TNXB | Ssm | 12 | 75 | 16% | cbioportal |
| 10 | FBN3 | Ssm | 11 | 75 | 14.7% | cbioportal |
| 9 | DNAH11 | Ssm | 11 | 75 | 14.7% | cbioportal |
| 8 | ADCY10 | Ssm | 11 | 75 | 14.7% | cbioportal |
| 11 | LORICRIN | Ssm | 11 | 75 | 14.7% | cbioportal |
| 12 | CACNA1H | Ssm | 10 | 75 | 13.3% | cbioportal |
| 15 | HEATR1 | Ssm | 10 | 75 | 13.3% | cbioportal |
| 13 | FAM83H | Ssm | 10 | 75 | 13.3% | cbioportal |
| 16 | LAMA5 | Ssm | 10 | 75 | 13.3% | cbioportal |
| 17 | MYO15A | Ssm | 10 | 75 | 13.3% | cbioportal |
| 14 | FCGBP | Ssm | 10 | 75 | 13.3% | cbioportal |
| 18 | TG | Ssm | 10 | 75 | 13.3% | cbioportal |
| 28 | LAMA1 | Ssm | 9 | 75 | 12% | cbioportal |
| 27 | GREB1 | Ssm | 9 | 75 | 12% | cbioportal |
| 26 | GPRIN2 | Ssm | 9 | 75 | 12% | cbioportal |
| 21 | COL18A1 | Ssm | 9 | 75 | 12% | cbioportal |
| 25 | F5 | Ssm | 9 | 75 | 12% | cbioportal |
| 24 | EPPK1 | Ssm | 9 | 75 | 12% | cbioportal |
| 19 | ABCA13 | Ssm | 9 | 75 | 12% | cbioportal |
| 23 | DNAH3 | Ssm | 9 | 75 | 12% | cbioportal |
| 22 | DNAH10 | Ssm | 9 | 75 | 12% | cbioportal |
| 39 | ZNF469 | Ssm | 9 | 75 | 12% | cbioportal |
| 37 | SPEG | Ssm | 9 | 75 | 12% | cbioportal |
| 36 | PRRC2C | Ssm | 9 | 75 | 12% | cbioportal |
Data updated 22 days agoSource updated 2026-01-05