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Intermediate Soft Tissue Neoplasm — Research · CancerIndex

Cancers
Neoplasm
Neoplasm by Site
Connective and Soft Tissue Neoplasm
Soft Tissue Neoplasm
Intermediate Soft Tissue Neoplasm

Subtype

Intermediate Soft Tissue Neoplasm

CI-CAN-00001021Explore in graph →

Non-malignant32 active trials42 evidence items

NCIt: C7653

Overview
Statistics
Survival
Genomics
Variants & evidence42
Drugs5
Trials136
Research
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Research activity

PubMed record counts

Each count is the number of PubMed records returned by the exact query shown, at the time it was run. Counts are research-activity signals, not quality measures.

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Literature

Linked publications (31)

Publications linked to this entity or its descendants, newest first, 25 per page. Link method and validation status are shown; 'candidate' links have not been reviewed.

pubmedProvenance

Source: PubMed (NLM)
Dataset: PubMed E-utilities
Retrieved: Sep 8, 2026
Layer: normalized (units and labels harmonized; values unchanged)

PublishedShowing 1–25 of 31 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

Targeting ALK With Crizotinib in Pediatric Anaplastic Large Cell Lymphoma and Inflammatory Myofibroblastic Tumor: A Children's Oncology Group Study.
· J Clin Oncol · 2017 · PMID 28787259 · validated civic_curation pubmed
Long-term effects of crizotinib in ALK-positive tumors (excluding NSCLC): A phase 1b open-label study.
· Am J Hematol · 2018 · PMID 29352732 · validated civic_curation pubmed
Safety and activity of crizotinib for paediatric patients with refractory solid tumours or anaplastic large-cell lymphoma: a Children's Oncology Group phase 1 consortium study.
· Lancet Oncol · 2013 · PMID 23598171 · validated civic_curation pubmed
Specific mutations in the beta-catenin gene (CTNNB1) correlate with local recurrence in sporadic desmoid tumors.
· Am J Pathol · 2008 · PMID 18832571 · validated civic_curation pubmed
CTNNB1 mutation analysis is a useful tool for the diagnosis of desmoid tumors: a study of 260 desmoid tumors and 191 potential morphologic mimics.
· Mod Pathol · 2012 · PMID 22766794 · validated civic_curation pubmed
β-Catenin mutation status and outcomes in sporadic desmoid tumors.
· Oncologist · 2013 · PMID 23960186 · validated civic_curation pubmed
Dermatofibrosarcoma protuberans COL1A1-PDGFB fusion is identified in virtually all dermatofibrosarcoma protuberans cases when investigated by newly developed multiplex reverse transcription polymerase chain reaction and fluorescence in situ hybridization assays.

Showing 1–25 of 31 publications

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· Hum Pathol · 2008 · PMID 17950782 · validated civic_curation pubmed

Prognostic value of CTNNB1 gene mutation in primary sporadic aggressive fibromatosis.

· Ann Surg Oncol · 2015 · PMID 25341748 · validated civic_curation pubmed

Entrectinib in children and young adults with solid or primary CNS tumors harboring NTRK, ROS1, or ALK aberrations (STARTRK-NG).

· Neuro Oncol · 2022 · PMID 35395680 · validated civic_curation pubmed

Identification of t(17;22)(q22;q13) (COL1A1/PDGFB) in dermatofibrosarcoma protuberans by fluorescence in situ hybridization in paraffin-embedded tissue microarrays.

· Hum Pathol · 2011 · PMID 21111450 · validated civic_curation pubmed

Diagnosis of known sarcoma fusions and novel fusion partners by targeted RNA sequencing with identification of a recurrent ACTB-FOSB fusion in pseudomyogenic hemangioendothelioma.

· Mod Pathol · 2019 · PMID 30459475 · validated civic_curation pubmed

Molecular genetic characterization of the genomic ACTB-GLI fusion in pericytoma with t(7;12).

· Biochem Biophys Res Commun · 2004 · PMID 15555571 · validated civic_curation pubmed

Detection of COL1A1-PDGFB fusion transcripts and PDGFB/PDGFRB mRNA expression in dermatofibrosarcoma protuberans.

· Mod Pathol · 2007 · PMID 17431412 · validated civic_curation pubmed

Genomic alterations of dermatofibrosarcoma protuberans revealed by whole-genome sequencing.

· Br J Dermatol · 2022 · PMID 35441365 · validated civic_curation pubmed

A novel SERPINE1-FOSB fusion gene results in transcriptional up-regulation of FOSB in pseudomyogenic haemangioendothelioma.

· J Pathol · 2014 · PMID 24374978 · validated civic_curation pubmed

EWSR1-CREB1 and EWSR1-ATF1 fusion genes in angiomatoid fibrous histiocytoma.

· Clin Cancer Res · 2007 · PMID 18094413 · validated civic_curation pubmed

EWSR1-CREB1 is the predominant gene fusion in angiomatoid fibrous histiocytoma.

· Genes Chromosomes Cancer · 2007 · PMID 17724745 · validated civic_curation pubmed

Crizotinib in ALK-rearranged inflammatory myofibroblastic tumor.

· N Engl J Med · 2010 · PMID 20979472 · validated civic_curation pubmed

Recurrent involvement of 2p23 in inflammatory myofibroblastic tumors.

· Cancer Res · 1999 · PMID 10383129 · validated civic_curation pubmed

MALAT1 functions as a transcriptional promoter of MALAT1::GLI1 fusion for truncated GLI1 protein expression in cancer.

· BMC Cancer · 2023 · PMID 37165307 · validated civic_curation pubmed

Fusion of the Genes WWTR1 and FOSB in Pseudomyogenic Hemangioendothelioma.

· Cancer Genomics Proteomics · 2019 · PMID 31243110 · validated civic_curation pubmed

Gastroblastoma harbors a recurrent somatic MALAT1-GLI1 fusion gene.

· Mod Pathol · 2017 · PMID 28731043 · validated civic_curation pubmed

The neuroblastoma-associated F1174L ALK mutation causes resistance to an ALK kinase inhibitor in ALK-translocated cancers.

· Cancer Res · 2010 · PMID 21030459 · validated civic_curation pubmed

Inflammatory myofibroblastic tumors harbor multiple potentially actionable kinase fusions.

· Cancer Discov · 2014 · PMID 24875859 · validated civic_curation pubmed

A favorable outcome of advanced dermatofibrosarcoma protuberans under treatment with sunitinib after imatinib failure.

· Onco Targets Ther · 2018 · PMID 29760553 · validated civic_curation pubmed