Subtype
Intermediate Soft Tissue Neoplasm
CI-CAN-00001021Explore in graph →
Non-malignant32 active trials42 evidence items
- NCIt
- C7653
Loading cancer entity…
Subtype
CI-CAN-00001021Explore in graph →
Clinical trials
136 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07755176 | Patient-reported Outcomes Following Percutaneous Ablation of Desmoid Tumors | enrolling by invitation | — | 30 | Mayo ClinicOTHER | 1 | Sep 29, 2026 | clinicaltrials |
| NCT07158892 | Understanding Patient Preferences When Deciding on a Voluntary Musculoskeletal Test | not yet recruiting | N/A | 220 | University of Texas at AustinOTHER | 1 | Sep 22, 2026 | clinicaltrials |
| NCT07170644 |
| A Study of Nirogacestat in Japanese Adults With Desmoid Tumors/Aggressive Fibromatosis (DT/AF) |
| active not recruiting |
| Phase 2 |
| 20 |
| SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, GermanyINDUSTRY |
| 1 |
| Sep 15, 2026 |
| clinicaltrials |
| NCT07176689 | Nirogacestat in Premenopausal Females With Desmoid Tumor/Aggressive Fibromatosis (DT/AF) | recruiting | Phase 4 | 50 | SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, GermanyINDUSTRY | 6 | Sep 14, 2026 | clinicaltrials |
| NCT05949099 | Study of Cryoablation and Nirogacestat for Desmoid Tumor | recruiting | Phase 2 | 28 | Nam BuiOTHER | 1 | Sep 10, 2026 | clinicaltrials |
| NCT02402244 | Project: Every Child for Younger Patients With Cancer | recruiting | — | 75,000 | Children's Oncology GroupNETWORK | 6 | Aug 25, 2026 | clinicaltrials |
| NCT04851119 | Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors | recruiting | Phase 1 / Phase 2 | 147 | Children's Oncology GroupNETWORK | 1 | Aug 25, 2026 | clinicaltrials |
| NCT03785964 | Nirogacestat for Adults With Desmoid Tumor/Aggressive Fibromatosis (DT/AF)(DeFi) | completed | Phase 3 | 142 | SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, GermanyINDUSTRY | 7 | Aug 20, 2026 | clinicaltrials |
| NCT06239272 | NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) | recruiting | Phase 1 / Phase 2 | 139 | St. Jude Children's Research HospitalOTHER | 1 | Aug 3, 2026 | clinicaltrials |
| NCT04195399 | A Study of a New Drug, Nirogacestat, for Treating Desmoid Tumors That Cannot be Removed by Surgery | active not recruiting | Phase 2 | 31 | Children's Oncology GroupNETWORK | 5 | Jul 30, 2026 | clinicaltrials |
| NCT06330545 | Radiation Therapy for Dupuytren's Contracture Following Non-Surgical Release | recruiting | N/A | 95 | Dartmouth-Hitchcock Medical CenterOTHER | 1 | Jul 28, 2026 | clinicaltrials |
| NCT07227649 | NAC-REPAIR for Post-surgical Pain | not yet recruiting | Phase 2 | 80 | University of ArizonaOTHER | 1 | Jul 17, 2026 | clinicaltrials |
| NCT06248866 | Effect Of Extracorporeal Shock Wave Therapy On Ultrasonography Changes In Patients With Palmar Fibromatosis: A Randomized Controlled Trial(ESWT) | completed | N/A | 60 | Cairo UniversityOTHER | 1 | Jul 14, 2026 | clinicaltrials |
| NCT06151197 | Study to Assess EN3835 in the Treatment of Plantar Fibromatosis (Also Known as Ledderhose Disease)(STRIDE) | completed | Phase 3 | 436 | Endo USA Inc., a Keenova Therapeutics CompanyINDUSTRY | 2 | Jul 13, 2026 | clinicaltrials |
| NCT02066181 | Sorafenib Tosylate in Treating Patients With Desmoid Tumors or Aggressive Fibromatosis | completed | Phase 3 | 87 | National Cancer Institute (NCI)NIH | 2 | Jun 24, 2026 | clinicaltrials |
| NCT07661342 | DEPART Study at Yale(Dupuytren's) | not yet recruiting | Phase 3 | 158 | Yale UniversityOTHER | 1 | Jun 22, 2026 | clinicaltrials |
| NCT07656909 | Low- vs High-Dose Sirolimus With Prednisolone for KHE and KMP | recruiting | Phase 2 / Phase 3 | 76 | Yi JiOTHER | 1 | Jun 18, 2026 | clinicaltrials |
| NCT02180867 | Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery | completed | Phase 2 / Phase 3 | 140 | National Cancer Institute (NCI)NIH | 3 | Jun 17, 2026 | clinicaltrials |
| NCT02834013 | Nivolumab and Ipilimumab in Treating Patients With Rare Tumors | active not recruiting | Phase 2 | 798 | National Cancer Institute (NCI)NIH | 2 | Jun 17, 2026 | clinicaltrials |
| NCT07646080 | Exploratory Study on Toripalimab and Anlotinib Combined With Standard Chemotherapy for Refractory Dermatofibrosarcoma Protuberans | not yet recruiting | Phase 2 | 20 | Yanjie Zhang, MDOTHER | 0 | Jun 16, 2026 | clinicaltrials |
| NCT07640425 | Safety and Efficacy Study of Collagenase CNT201 Injection for Treatment of Dupuytren's Contracture | recruiting | Phase 1 / Phase 2 | 60 | CONNEXTINDUSTRY | 1 | Jun 12, 2026 | clinicaltrials |
| NCT04871282 | A Study of AL102 in Patients With Progressing Desmoid Tumors(RINGSIDE) | active not recruiting | Phase 2 / Phase 3 | 198 | Immunome, Inc.INDUSTRY | 11 | Jun 8, 2026 | clinicaltrials |
| NCT04281381 | Observing People With Desmoid-Type Fibromatosis | recruiting | — | 100 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | May 15, 2026 | clinicaltrials |
| NCT06660121 | Electrochemotherapy for Desmoid Tumors(ECT-DESMO) | withdrawn | — | 0 | Istituto Ortopedico RizzoliOTHER | 1 | May 14, 2026 | clinicaltrials |
| NCT05041036 | Individual Patient Compassionate Use of Nirogacestat | available | — | — | SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, GermanyINDUSTRY | 0 | May 8, 2026 | clinicaltrials |
| NCT07541430 | A Study in Adults With Desmoid Tumors | recruiting | Phase 2 | 50 | Elpiscience (Suzhou) Biopharma, Ltd.INDUSTRY | 1 | Apr 30, 2026 | clinicaltrials |
| NCT03192020 | Trial Comparing Treatment Strategies in Dupuytren's Contracture(DETECT) | active not recruiting | Phase 4 | 302 | Tampere UniversityOTHER | 1 | Apr 29, 2026 | clinicaltrials |
| NCT02867033 | National Clinical-biological Prospective Cohort of Incident Cases of Aggressive Fibromatosis (ALTITUDES)(ALTITUDES) | active not recruiting | N/A | 628 | Centre Oscar LambretOTHER | 1 | Mar 30, 2026 | clinicaltrials |
| NCT05160922 | Crizotinib Continuation Clinical Study | active not recruiting | Phase 4 | 27 | PfizerINDUSTRY | 5 | Mar 30, 2026 | clinicaltrials |
| NCT05152173 | Efficacy, Safety, and Tolerability, of EN3835 vs Placebo in the Treatment of Plantar Fibromatosis | completed | Phase 2 | 176 | Endo USA Inc., a Keenova Therapeutics CompanyINDUSTRY | 1 | Mar 27, 2026 | clinicaltrials |
| NCT07496242 | Immunological Phenotype of Desmoid-fibromatosis-affected Patients. | recruiting | — | 200 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 2 | Mar 27, 2026 | clinicaltrials |
| NCT04122313 | Post-contracture Release Radiation for Dupuytren's Disease | recruiting | — | 50 | University of MinnesotaOTHER | 1 | Mar 19, 2026 | clinicaltrials |
| NCT03155854 | The Effects of Prophylactic Limited Palmar Fasciectomy on Surgical Outcomes and Scarring | recruiting | N/A | 50 | Mayo ClinicOTHER | 1 | Mar 16, 2026 | clinicaltrials |
| NCT07461246 | Familial Adenomatous Poliposys Italian Network (Rete Italiana Poliposi Adenomatosa Familiare)(RIPAF) | active not recruiting | — | 1,500 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 1 | Mar 10, 2026 | clinicaltrials |
| NCT07443371 | Effect of Transfer Energy Capacitive and Resistive Therapy on Palmar Fibromatosis | not yet recruiting | N/A | 36 | Cairo UniversityOTHER | 1 | Mar 2, 2026 | clinicaltrials |
| NCT05111964 | HIFU Ablation of Soft Tissue Sarcoma(SarcAblate) | recruiting | N/A | 10 | Oxford University Hospitals NHS TrustOTHER | 1 | Feb 4, 2026 | clinicaltrials |
| NCT02476305 | Evaluation of the Cryodestruction of Non Abdominopelvic Desmoid Tumors in Patients Progressing Despite Medical Treatment(CRYODESMO01) | completed | N/A | 50 | University Hospital, Strasbourg, FranceOTHER | 1 | Jan 20, 2026 | clinicaltrials |
| NCT04925609 | Brigatinib in Pediatric and Young Adult Patients With ALK+ ALCL, IMT or Other Solid Tumors(Briga-PED) | recruiting | Phase 1 / Phase 2 | 65 | Princess Maxima Center for Pediatric OncologyOTHER | 2 | Dec 5, 2025 | clinicaltrials |
| NCT06081400 | Cryoablation Versus Medical Therapy in Desmoid Tumors Progressing After Watchful Waiting(CRYODESMO-02) | recruiting | N/A | 150 | University Hospital, Strasbourg, FranceOTHER | 1 | Nov 19, 2025 | clinicaltrials |
| NCT06945887 | Treatment of Desmoid Fibromatosis With Arterial Embolization(TAE-DESMO) | recruiting | — | 20 | Istituto Ortopedico RizzoliOTHER | 1 | Sep 12, 2025 | clinicaltrials |
| NCT02547831 | Tailored Beta-catenin Mutational Approach in Extra-abdominal Sporadic Desmoids Tumor Patients | completed | — | 100 | Fondazione IRCCS Istituto Nazionale dei Tumori, MilanoOTHER | 1 | Sep 11, 2025 | clinicaltrials |
| NCT06258421 | Burden of Disease and Living Situation in Desmoid Patients(PROSa Desmoid) | completed | — | 100 | Technische Universität DresdenOTHER | 1 | Aug 24, 2025 | clinicaltrials |
| NCT03407820 | Nylon Versus Chromic Gut Sutures for Minor Hand Surgery | completed | N/A | 112 | University of Texas at AustinOTHER | 1 | Jul 31, 2025 | clinicaltrials |
| NCT02228889 | RCT of Two Noncrosslinked Porcine Acellular Dermal Matrices in Ab Wall Reconstruction | completed | N/A | 46 | Jeffrey JanisOTHER | 1 | Jun 6, 2025 | clinicaltrials |
| NCT05254457 | Long-Term Safety, Efficacy, and Durability of EN3835 in the Treatment and Retreatment of Plantar Fibromatosis | completed | Phase 3 | 145 | Endo USA Inc., a Keenova Therapeutics CompanyINDUSTRY | 1 | Mar 21, 2025 | clinicaltrials |
| NCT04874870 | Effectiveness of Splinting After Collagenase Injection | completed | Phase 3 | 80 | Foundation for Orthopaedic Research and EducationOTHER | 1 | Feb 26, 2025 | clinicaltrials |
| NCT03190174 | Nivolumab (Opdivo®) Plus ABI-009 (Nab-rapamycin) for Advanced Sarcoma and Certain Cancers | completed | Phase 1 / Phase 2 | 34 | Sarcoma Oncology Research Center, LLCOTHER | 1 | Feb 17, 2025 | clinicaltrials |
| NCT06806410 | The Efficacy of Liposomal Bupivacaine in Ultrasound Guided Supraclavicular Nerve Blocks for Hand and Wrist Surgery | active not recruiting | Phase 4 | 120 | St. Luke's Hospital, PennsylvaniaOTHER | 1 | Feb 6, 2025 | clinicaltrials |
| NCT06788847 | Evaluating Ultrasound-Guided Needle Knife for Dupuytren's Contracture(DC-US) | recruiting | N/A | 30 | Mohamed Maher Ismail Ahmed ElashmawyOTHER | 1 | Jan 27, 2025 | clinicaltrials |
| NCT02076906 | MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors | completed | Phase 1 | 7 | AeRang KimOTHER | 1 | Jan 1, 2025 | clinicaltrials |
Data updated 8 hours agoSource updated Sep 29, 2026source: clinicaltrials