Publication
EWSR1-CREB1 is the predominant gene fusion in angiomatoid fibrous histiocytoma.
Authors not recorded
Genes Chromosomes Cancer2007PMID 17724745stubpubmedProvenance
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
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Linked entities
Linked entities (3)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 3
- cancerAngiomatoid Fibrous Histiocytomacivic_curation1.00
- geneCREB1civic_curation1.00
- variantCREB1 Fusioncivic_curation1.00
Curated evidence
Evidence citing this paper (1)
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 17724745
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| CREB1 Fusion1 | ||||||||
| (diagnostic) | Angiomatoid Fibrous Histiocytoma | Diagnostic | B | Supports Positive | 3 | accepted | EID12855In this study, the authors analyzed 9 cases of angiomatoid fibrous histiocytoma (AFH). The EWSR1::CREB1 fusion was identified as the predominant molecular alteration, detected in 8 of 9 tumors by RT‑P… (full text at CIViC) PMID 17724745 · Antonescu et al., 2007 · Open in CIViC | civic |