Subtype
Hepatocellular Carcinoma
CI-CAN-00002853HCC · LIHCExplore in graph →
693 active trials13 approved drugs9 evidence items
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Subtype
CI-CAN-00002853HCC · LIHCExplore in graph →
Clinical trials
3,126 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (357)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT01273662 | Axitinib as Second-line Treatment for Advanced Hepatocellular Carcinoma | completed | Phase 2 | 45 | National Taiwan University HospitalOTHER | 1 | Feb 9, 2017 | clinicaltrials |
| NCT03048123 | HAIC Versus TACE for Large and Unresectable Hepatocellular Carcinoma Staged BCLC A/B | completed | Phase 2 | 79 | Sun Yat-sen UniversityOTHER | 1 | Feb 9, 2017 | clinicaltrials |
| Study of Apatinib in Advanced Hepatocellular Carcinoma(HCC)(HCC) |
| unknown |
| Phase 2 |
| 30 |
| Tianjin Medical University Cancer Institute and HospitalOTHER |
| 1 |
| Feb 8, 2017 |
| clinicaltrials |
| NCT00273312 | Patupilone Activity in Advanced/Metastatic Hepatocellular Carcinoma | completed | Phase 2 | 25 | Novartis PharmaceuticalsINDUSTRY | 4 | Feb 7, 2017 | clinicaltrials |
| NCT00516165 | RAD001 in Advanced Hepatocellular Carcinoma | completed | Phase 1 / Phase 2 | 28 | Massachusetts General HospitalOTHER | 1 | Feb 7, 2017 | clinicaltrials |
| NCT02447679 | Oral Thalidomide and Tegafur-uracil to Decrease Hepatocellular Carcinoma Recurrence | completed | Phase 2 | 40 | Chang Gung Memorial HospitalOTHER | 1 | Feb 7, 2017 | clinicaltrials |
| NCT03045419 | Added Value of Gadoxetic Acid-enhanced Liver MRI | completed | — | 130 | Seoul National University HospitalOTHER | 1 | Feb 7, 2017 | clinicaltrials |
| NCT01163526 | Perfusion CT as a Predictor of Treatment Response in Patients With Hepatic Malignancies | terminated | — | 13 | Stanford UniversityOTHER | 1 | Jan 30, 2017 | clinicaltrials |
| NCT00465023 | Proton Beam Irradiation for the Treatment of Unresectable Hepatocellular Cancer or Hepatic Metastases | completed | N/A | 16 | Massachusetts General HospitalOTHER | 0 | Jan 20, 2017 | clinicaltrials |
| NCT02315989 | Early-Phase Safety of Proton Therapy Equipment | completed | N/A | 6 | Chang Gung Memorial HospitalOTHER | 1 | Jan 13, 2017 | clinicaltrials |
| NCT03020342 | HBV-host cfDNA as Minimal Residual Tumor Marker for HBV-related HCC | unknown | — | 50 | National Taiwan University HospitalOTHER | 1 | Jan 13, 2017 | clinicaltrials |
| NCT02319200 | Primary Prevention Hepatocellular Carcinoma by Metformin(METFOVIR) | terminated | Phase 3 | 11 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Jan 11, 2017 | clinicaltrials |
| NCT01966133 | TACE as an Adjuvant Therapy After Hepatectomy for HCC | unknown | Phase 3 | 280 | Jia FanOTHER | 1 | Jan 9, 2017 | clinicaltrials |
| NCT03007212 | Outcome of Transarterial Chemo-embolization (TACE) in Hepatocellular Carcinoma Patients With Partial Portal Vein Thrombosis | completed | Phase 4 | 30 | Ain Shams UniversityOTHER | 0 | Jan 2, 2017 | clinicaltrials |
| NCT02987699 | Phase II Study of HAIC Using Cisplatin,Leucovorin and 5-Fluorouracil | unknown | Phase 2 | 54 | Sun Yat-sen UniversityOTHER | 1 | Dec 28, 2016 | clinicaltrials |
| NCT01767597 | Application of HBV Rapid Tests as a Tool for Wide-Use Screening(OPTISCREEN-B) | completed | N/A | 1,000 | Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'BaOTHER | 1 | Dec 13, 2016 | clinicaltrials |
| NCT01790633 | Pilot Study Evaluating the Use of Simultaneous HBV, HCV, and HIV Rapid Tests(OPTISCREEN-III) | completed | N/A | 327 | Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'BaOTHER | 1 | Dec 13, 2016 | clinicaltrials |
| NCT02990351 | Efficacy of Loco-regional Treatment for Hepatocellular Carcinoma Prior to Living Donor Liver Transplantation in Egypt | completed | — | 29 | Ain Shams UniversityOTHER | 0 | Dec 13, 2016 | clinicaltrials |
| NCT02985034 | Safety Margin Assessment After RFA Using the Registration of Pre-ablation MRI and Post-ablation CT | completed | — | 77 | Seoul National University HospitalOTHER | 1 | Dec 7, 2016 | clinicaltrials |
| NCT02839954 | CAR-pNK Cell Immunotherapy in MUC1 Positive Relapsed or Refractory Solid Tumor | unknown | Phase 1 / Phase 2 | 10 | PersonGen BioTherapeutics (Suzhou) Co., Ltd.INDUSTRY | 1 | Dec 6, 2016 | clinicaltrials |
| NCT02587689 | Phase I/II Study of Anti-Mucin1 (MUC1) CAR T Cells for Patients With MUC1+ Advanced Refractory Solid Tumor | unknown | Phase 1 / Phase 2 | 20 | PersonGen BioTherapeutics (Suzhou) Co., Ltd.INDUSTRY | 1 | Dec 5, 2016 | clinicaltrials |
| NCT01335074 | Temsirolimus + Sorafenib in Advanced Hepatocellular Carcinoma (HCC) | withdrawn | Phase 1 / Phase 2 | 0 | Philipps University MarburgOTHER | 1 | Nov 15, 2016 | clinicaltrials |
| NCT01078415 | Pilot Study of Irreversible Electroporation (IRE) to Treat Early-Stage Primary Liver Cancer (HCC) | completed | N/A | 26 | Angiodynamics, Inc.INDUSTRY | 4 | Nov 8, 2016 | clinicaltrials |
| NCT02959151 | A Study of Chimeric Antigen Receptor T Cells Combined With Interventional Therapy in Advanced Liver Malignancy | unknown | Phase 1 / Phase 2 | 20 | Shanghai GeneChem Co., Ltd.INDUSTRY | 1 | Nov 8, 2016 | clinicaltrials |
| NCT01308723 | A Dose-Finding and Exploratory Study of RO5323441 in Combination With Sorafenib in Patients With Hepatocellular Carcinoma | completed | Phase 1 | 6 | Hoffmann-La RocheINDUSTRY | 1 | Nov 2, 2016 | clinicaltrials |
| NCT01897038 | A Safety, Tolerability, and Pharmacokinetics Study of Onartuzumab as Single Agent or in Combination With Sorafenib in Participants With Advanced Hepatocellular Carcinoma | completed | Phase 1 | 9 | Hoffmann-La RocheINDUSTRY | 4 | Nov 2, 2016 | clinicaltrials |
| NCT02576964 | A Study of Capecitabine (Xeloda) and Peginterferon Alfa-2a (Pegasys) in Treatment-Naive Participants With Advanced Liver Cancer | completed | Phase 2 | 16 | Hoffmann-La RocheINDUSTRY | 3 | Nov 2, 2016 | clinicaltrials |
| NCT02738697 | Adjuvant Chemotherapy With FOLFOX in HCC Patients After Resection | unknown | Phase 3 | 290 | Sun Yat-sen UniversityOTHER | 1 | Nov 2, 2016 | clinicaltrials |
| NCT00427973 | AZD2171 in Treating Patients With Locally Advanced Unresectable or Metastatic Liver Cancer | terminated | Phase 2 | 17 | National Cancer Institute (NCI)NIH | 1 | Oct 31, 2016 | clinicaltrials |
| NCT00606385 | Prospective Randomized Trial of Laparoscopic Versus Open Liver Resection for HCC(HCC) | unknown | N/A | 84 | Seoul National University HospitalOTHER | 1 | Oct 28, 2016 | clinicaltrials |
| NCT02813096 | Study of Folfox4 Chemotherapy Regimen to Prevent Early Postoperative Recurrence for HCC-PVTT Patients | unknown | N/A | 500 | Guangxi Medical UniversityOTHER | 0 | Oct 25, 2016 | clinicaltrials |
| NCT02523053 | Effect of Intraoperative Controlled Release 5-Fluorouracil Therapy on Recurrence in Hepatocellular Carcinoma Patients | unknown | N/A | 160 | Eastern Hepatobiliary Surgery HospitalOTHER | 1 | Oct 21, 2016 | clinicaltrials |
| NCT02630108 | TACE Combined With Synchronous Radiofrequency /Microwave Ablation to Treat Large and Huge Hepatocellular Carcinoma | unknown | Phase 3 | 280 | Shanghai Zhongshan HospitalOTHER | 1 | Oct 18, 2016 | clinicaltrials |
| NCT00812175 | Global Investigation of Therapeutic Decisions in Hepatocellular Carcinoma and of Its Treatment With Sorafenib(GIDEON) | completed | — | 3,371 | BayerINDUSTRY | 39 | Oct 17, 2016 | clinicaltrials |
| NCT00508001 | Phase II Study of Best Support Care (BSC) Plus ZD6474(Vandetanib) in Patients With Inoperable Hepatocellular Carcinoma (HCC) | completed | Phase 2 | 67 | Genzyme, a Sanofi CompanyINDUSTRY | 1 | Oct 10, 2016 | clinicaltrials |
| NCT01522820 | Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumors | completed | Phase 1 | 18 | Roswell Park Cancer InstituteOTHER | 1 | Oct 4, 2016 | clinicaltrials |
| NCT01798134 | Microparticle Enhanced Cytotoxic Transarterial Embolization Therapy in Hepatocellular Carcinoma(MIRACLE I) | completed | N/A | 25 | Boston Scientific CorporationINDUSTRY | 1 | Oct 3, 2016 | clinicaltrials |
| NCT01829971 | A Multicenter Phase I Study of MRX34, MicroRNA miR-RX34 Liposomal Injection | terminated | Phase 1 | 155 | Mirna Therapeutics, Inc.INDUSTRY | 2 | Sep 27, 2016 | clinicaltrials |
| NCT00846131 | Y-90 Alone or With Sorafenib for Pre-Transplant Hepatocellular Carcinoma | completed | Phase 1 | 24 | Northwestern UniversityOTHER | 1 | Sep 15, 2016 | clinicaltrials |
| NCT02809534 | A Study of Anlotinib in Patients With Hepatocellular Carcinoma(ALTER0802) | unknown | Phase 2 | 60 | Chia Tai Tianqing Pharmaceutical Group Co., Ltd.INDUSTRY | 1 | Sep 7, 2016 | clinicaltrials |
| NCT01964235 | Study of Efficacy and Safety INC280 in Patients With Advanced Hepatocellular Carcinoma | withdrawn | Phase 2 | 0 | Novartis PharmaceuticalsINDUSTRY | 7 | Sep 1, 2016 | clinicaltrials |
| NCT02886897 | A Study of Combinations of D-CIK Immunotherapy And Anti-PD-1 In Refractory Solid Tumors | unknown | Phase 1 / Phase 2 | 50 | Sun Yat-sen UniversityOTHER | 1 | Sep 1, 2016 | clinicaltrials |
| NCT02882659 | Dendritic Killer Cell-based Immunotherapy for Solid Tumors | unknown | Phase 1 | 18 | FullHope Biomedical Co., Ltd.INDUSTRY | 0 | Aug 30, 2016 | clinicaltrials |
| NCT02880306 | Hepatocellular Carcinoma and Rheumatoid Arthritis | completed | — | 741,379 | Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical FoundationOTHER | 0 | Aug 26, 2016 | clinicaltrials |
| NCT01575574 | Magnetic Resonance With Gadoxetic Acid for the Diagnosis of Hepatocellular Carcinoma in Patients With Liver Cirrhosis. Evaluation of Its Impact for the Non-invasive Diagnosis(PRIGA) | completed | Phase 4 | 74 | Sara VareaOTHER | 1 | Aug 23, 2016 | clinicaltrials |
| NCT01777594 | Study of G-202 (Mipsagargin) as Second-Line Therapy Following Sorafenib in Hepatocellular Carcinoma(G-202-003) | completed | Phase 2 | 25 | GenSpera, Inc.INDUSTRY | 1 | Aug 23, 2016 | clinicaltrials |
| NCT01911000 | Effectiveness and Safety of the Simultaneous Radiotherapy and Hyperthermia After Transarterial Chemoembolization in Hepatocellular Carcinoma Patients Combined With Portal Vein Tumor Thrombosis | completed | Phase 2 | 69 | Samsung Medical CenterOTHER | 1 | Aug 22, 2016 | clinicaltrials |
| NCT01733004 | A Phase 1 Study of MM-141 in Patients With Advanced Solid Tumors | completed | Phase 1 | 42 | Merrimack PharmaceuticalsINDUSTRY | 2 | Aug 4, 2016 | clinicaltrials |
| NCT02847767 | Dynamic Contrast Enhanced HCC SABR Liver Study | unknown | N/A | 20 | British Columbia Cancer AgencyOTHER | 1 | Jul 28, 2016 | clinicaltrials |
Data updated 23 days agoSource updated Feb 9, 2017source: clinicaltrials