Subtype
Hepatocellular Carcinoma
CI-CAN-00002853HCC · LIHCExplore in graph →
693 active trials13 approved drugs9 evidence items
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Subtype
CI-CAN-00002853HCC · LIHCExplore in graph →
Clinical trials
3,126 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
Computedformula ci-trial-intel-v1 · interventional studies · entity + NCIt descendants · hover a figure for its formulaCompare cancersTerminated studies (357)
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT02859324 | A Safety and Efficacy Study of CC-122 in Combination With Nivolumab in Subjects With Unresectable Hepatocellular Carcinoma (HCC) | completed | Phase 1 / Phase 2 | 21 | CelgeneINDUSTRY | 4 | May 11, 2021 | clinicaltrials |
| NCT01908426 | Study of Cabozantinib (XL184) vs Placebo in Subjects With Hepatocellular Carcinoma Who Have Received Prior Sorafenib(CELESTIAL) | completed | Phase 3 | 707 | ExelixisINDUSTRY | 19 | May 6, 2021 |
| NCT02472249 | Pharmacological Manipulation of Intrahepatic Arterial Blood Flow in HCC | completed | Phase 4 | 10 | University Health Network, TorontoOTHER | 1 | Apr 28, 2021 | clinicaltrials |
| NCT02973204 | Circulating Tumor Cells and Tumor DNA in HCC and NET | completed | — | 167 | University of AarhusOTHER | 1 | Apr 28, 2021 | clinicaltrials |
| NCT03295006 | A TheraSphere® Advanced Dosimetry Retrospective Global Study in HCC(TARGET) | completed | — | 209 | Boston Scientific CorporationINDUSTRY | 8 | Apr 21, 2021 | clinicaltrials |
| NCT03706742 | STOP HCC: Mailed HCV Treatment Outreach Program for HCC Prevention | completed | N/A | 12,386 | University of Texas Southwestern Medical CenterOTHER | 1 | Apr 20, 2021 | clinicaltrials |
| NCT03741088 | Study to Evaluate VORTX Rx (Theresa)(Theresa) | completed | N/A | 8 | HistoSonics, Inc.INDUSTRY | 1 | Apr 20, 2021 | clinicaltrials |
| NCT04844112 | CT/MR-US Automatic Fusion System in Pre-procedure Planning for Radiofrequency Ablation | completed | N/A | 139 | Seoul National University HospitalOTHER | 0 | Apr 14, 2021 | clinicaltrials |
| NCT03851471 | Jiu-wei-zhen-xiao Granule for Advanced Hepatocellular Carcinoma | completed | Early Phase 1 | 10 | Zhong WangOTHER | 1 | Apr 9, 2021 | clinicaltrials |
| NCT01033240 | CS1008- in Combination With Sorafenib Compared to Sorafenib Alone in Subjects With Advanced Liver Cancer | completed | Phase 2 | 172 | Daiichi SankyoINDUSTRY | 4 | Apr 8, 2021 | clinicaltrials |
| NCT01915589 | Refametinib(BAY86-9766) in RAS Mutant Hepatocellular Carcinoma (HCC) | completed | Phase 2 | 16 | BayerINDUSTRY | 17 | Apr 8, 2021 | clinicaltrials |
| NCT01915602 | Refametinib in Combination With Sorafenib in RAS Mutant Hepatocellular Carcinoma (HCC) | completed | Phase 2 | 14 | BayerINDUSTRY | 21 | Apr 8, 2021 | clinicaltrials |
| NCT00877136 | A Treatment of Unresectable Hepatocellular Carcinoma With TheraSphere® | completed | — | 18 | St. Joseph Hospital of OrangeOTHER | 1 | Apr 6, 2021 | clinicaltrials |
| NCT01755767 | Study of Tivantinib in Subjects With Inoperable Hepatocellular Carcinoma (HCC) Who Have Been Treated With One Prior Therapy(METIV-HCC) | completed | Phase 3 | 383 | Daiichi SankyoINDUSTRY | 16 | Apr 6, 2021 | clinicaltrials |
| NCT02953743 | Pharmacokinetic Study of E7080/Lenvatinib in Chinese Patients With Unresectable Hepatocellular Carcinoma (HCC) | completed | Phase 1 | 25 | Eisai Co., Ltd.INDUSTRY | 1 | Apr 1, 2021 | clinicaltrials |
| NCT04820712 | Surgical Therapy and Survival in HCC/ C.F. Zhang et al. | completed | — | 664 | Linzhu ZhaiOTHER | 1 | Apr 1, 2021 | clinicaltrials |
| NCT02670122 | Prospective Study to Evaluate Safety of Deb-TACE With 100µ Beads in Patients With Non Resectable HCC | completed | — | 131 | Instituto de Investigación Sanitaria de la Fundación Jiménez DíazOTHER | 1 | Mar 30, 2021 | clinicaltrials |
| NCT03888859 | ET1402L1-ARTEMIS™2 T Cells in Alpha Fetoprotein (AFP) Expressing Hepatocellular Carcinoma | completed | Early Phase 1 | 12 | First Affiliated Hospital Xi'an Jiaotong UniversityOTHER | 1 | Mar 29, 2021 | clinicaltrials |
| NCT01967823 | T Cell Receptor Immunotherapy Targeting NY-ESO-1 for Patients With NY-ESO-1 Expressing Cancer | completed | Phase 2 | 11 | National Cancer Institute (NCI)NIH | 1 | Mar 24, 2021 | clinicaltrials |
| NCT04813861 | Sequential Treatment of Hepatocellular Carcinoma by Transarterial Chemoembolization and Local Ablation or External Radiation(CELPerCutCHC) | completed | — | 57 | Central Hospital, Nancy, FranceOTHER | 1 | Mar 24, 2021 | clinicaltrials |
| NCT03375281 | Radiofrequency Ablation Using Octopus Electrodes for Small Hepatocellular Carcinoma With No-touch Technique | completed | N/A | 140 | Seoul National University HospitalOTHER | 1 | Mar 23, 2021 | clinicaltrials |
| NCT02832882 | RFA for Small HCC With No-touch Technique Using Octopus Electrode | completed | N/A | 118 | Seoul National University HospitalOTHER | 0 | Mar 22, 2021 | clinicaltrials |
| NCT03389126 | Phase II Study of Avelumab in Patients With Advanced Hepatocellular Carcinoma After Prior Sorafenib Treatment(AvelumabHCC) | completed | Phase 2 | 30 | Seoul National University HospitalOTHER | 1 | Mar 17, 2021 | clinicaltrials |
| NCT02642913 | Study of Enzalutamide With and Without Sorafenib in Advanced Hepatocellular Carcinoma Patients | completed | Phase 1 | 28 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Mar 5, 2021 | clinicaltrials |
| NCT04780789 | Volumetric Analysis of Hepatocellular Carcinoma After Transarterial Chemoembolization | completed | — | 61 | Brno University HospitalOTHER | 0 | Mar 4, 2021 | clinicaltrials |
| NCT03405909 | Standardized CEUS Algorithms for Diagnosis of HCC - Prospective German Multicenter Study(ESCULAP) | completed | — | 517 | University Hospital ErlangenOTHER | 1 | Mar 2, 2021 | clinicaltrials |
| NCT02693847 | Natural History of Liver Cirrhosis Diagnosed by Transient Elastography in HIV/HCV-coinfected Patients | completed | — | 446 | Hospital Universitario de ValmeOTHER | 1 | Feb 26, 2021 | clinicaltrials |
| NCT03338062 | A Pilot Study to Assess Theragnostically Planned Liver Radiation to Optimize Radiation Therapy | completed | N/A | 15 | Indiana UniversityOTHER | 1 | Feb 26, 2021 | clinicaltrials |
| NCT04771988 | Radioembolization for Hepatocellular Carcinoma With Portal Vein Tumoral Thrombosis | completed | — | 17 | IRCCS Azienda Ospedaliero-Universitaria di BolognaOTHER | 0 | Feb 25, 2021 | clinicaltrials |
| NCT03254121 | Genome Studies of Hepatocellular Carcinoma Developed in Hepatitis C Patients With Sustained Virological Response(HEPCASUS) | completed | — | 93 | Karolinska InstitutetOTHER | 1 | Feb 18, 2021 | clinicaltrials |
| NCT03382327 | Benefit of the Use of 3D Models and Tools in Hepatectomy Planning for Hepatocarcinomas(3D-HAPPI) | completed | N/A | 136 | IHU StrasbourgOTHER | 1 | Feb 10, 2021 | clinicaltrials |
| NCT04230642 | Multicenter Study to Evaluate a New Robotic Device for Image-guided Percutaneous Needle Placement | completed | N/A | 22 | Quantum SurgicalINDUSTRY | 1 | Feb 4, 2021 | clinicaltrials |
| NCT04072679 | Safety and Efficacy Study of Sintilimab Combined With IBI305 in Patients With Advanced Hepatocellular Carcinoma | completed | Phase 1 | 50 | Chinese Academy of Medical SciencesOTHER | 1 | Feb 1, 2021 | clinicaltrials |
| NCT01666756 | Chinese Herbal Formulation PHY906 and Sorafenib Tosylate in Treating Patients With Advanced Liver Cancer | completed | Phase 1 | 18 | City of Hope Medical CenterOTHER | 1 | Jan 27, 2021 | clinicaltrials |
| NCT01972672 | The Phase II Study of Icaritin in Patients With Advanced Hepatocellular Carcinoma | completed | Phase 2 | 70 | Beijing Shenogen Biomedical Co., LtdINDUSTRY | 1 | Jan 27, 2021 | clinicaltrials |
| NCT03663114 | A Post-marketing Observational Study on Risk Factors for Hepatic Encephalopathy in Participants With Unresectable Hepatocellular Carcinoma | completed | — | 713 | Eisai Inc.INDUSTRY | 1 | Jan 22, 2021 | clinicaltrials |
| NCT04721470 | Combined Therapy for Hepatocellular Carcinoma >3-<5 cm | completed | N/A | 278 | Zagazig UniversityOTHER_GOV | 0 | Jan 22, 2021 | clinicaltrials |
| NCT02572687 | A Study of Ramucirumab (LY3009806) Plus MEDI4736 in Participants With Advanced Gastrointestinal or Thoracic Malignancies | completed | Phase 1 | 85 | Eli Lilly and CompanyINDUSTRY | 8 | Jan 20, 2021 | clinicaltrials |
| NCT01246986 | A Study of LY2157299 in Participants With Hepatocellular Carcinoma | completed | Phase 2 | 204 | Eli Lilly and CompanyINDUSTRY | 7 | Jan 12, 2021 | clinicaltrials |
| NCT04510935 | Effects of Anesthetic Methods on Hepatic Cancer Cell Function in Vitro | completed | N/A | 35 | RenJi HospitalOTHER | 1 | Jan 8, 2021 | clinicaltrials |
| NCT04692454 | Investigation of Immune Modulation by Modern Acupuncture in Gastroenterologic Cancers | completed | N/A | 5 | Taipei Medical University WanFang HospitalOTHER | 1 | Dec 31, 2020 | clinicaltrials |
| NCT04687280 | Comparison of Multiphase and Monophasic Arterial Hepatic MRI in the Detection of Arterial Enhancement of CHC Nodules(CHIC MultiA) | completed | — | 153 | University Hospital, AngersOTHER_GOV | 0 | Dec 29, 2020 | clinicaltrials |
| NCT02082210 | A Study of Emibetuzumab in Combination With Ramucirumab (LY3009806) in Participants With Advanced Cancer | completed | Phase 1 / Phase 2 | 97 | Eli Lilly and CompanyINDUSTRY | 1 | Dec 19, 2020 | clinicaltrials |
| NCT02988440 | Study of Safety and Tolerability of PDR001 in Combination With Sorafenib and to Identify the Maximum Tolerated Dose and/or Phase 2 Dose for This Combination in Advanced Hepatocellular Patients | completed | Phase 1 | 20 | Novartis PharmaceuticalsINDUSTRY | 8 | Dec 19, 2020 | clinicaltrials |
| NCT01687673 | Phase II Combination of Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma | completed | Phase 2 | 29 | University of California, San FranciscoOTHER | 1 | Dec 7, 2020 | clinicaltrials |
| NCT04652947 | MR Quality + Diagnostic Performance for CHC Diagnosis - Gadoxetic Acid, Gadoteric Acid and P03277 Comparison | completed | — | 30 | University Hospital, AngersOTHER_GOV | 0 | Dec 3, 2020 | clinicaltrials |
| NCT01198704 | Study of Factors Predicting Tumor Recurrence After Liver Transplantation for Hepatocellular Carcinoma (HCC)(EFAPRE) | completed | — | 372 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Nov 20, 2020 | clinicaltrials |
| NCT01595243 | Effects of Telephone Consultations on Discharged Liver Cancer | completed | N/A | 254 | National Taiwan University HospitalOTHER | 1 | Nov 16, 2020 | clinicaltrials |
| NCT01264705 | Study of Bavituximab and Sorafenib In Patients With Advanced Liver Cancer | completed | Phase 1 / Phase 2 | 47 | University of Texas Southwestern Medical CenterOTHER | 1 | Nov 12, 2020 | clinicaltrials |
| NCT02658019 | Pembrolizumab (Keytruda) in Advanced Hepatocellular Carcinoma | completed | Phase 2 | 29 | Lynn Feun, MDOTHER | 1 | Nov 12, 2020 | clinicaltrials |
Data updated 23 days agoSource updated May 11, 2021source: clinicaltrials