Hematologic Malignancy
Hematologic Neoplasm Associated with Down Syndrome
CI-CAN-00005464Explore in graph →
Hematologic3 active trials
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Hematologic Malignancy
CI-CAN-00005464Explore in graph →
Data completeness2 / 7 dimensions
Computed from entity_counters.completeness · refreshed after each connector run
Definition
Hematologic neoplasms occurring in individuals with Down syndrome. There is an increased risk of acute leukemias in both children and adults with Down syndrome. In particular, the incidence of acute myeloid leukemia in Down syndrome children of less than five years of age is particularly high, it is usually an acute megakaryoblastic leukemia, and is associated with GATA1 gene mutation. This group of disorders also includes the entity transient abnormal myelopoiesis which occurs in neonates and is associated with GATA1 gene mutation.
Data updated 22 days agoSource updated 26.08e
Taxonomy
Several hierarchies coexist; edges are listed per hierarchy type with their source.
Anatomy
Data updated 18 hours agoSource updated unknowncounters aggregate over descendants
Names
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Key figures
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Data updated 18 hours agoSource updated unknownregistry figures: cdc-uscs · latest year available per metric · counters aggregate over descendants