Hematologic Malignancy
Transient Abnormal Myelopoiesis Associated with Down Syndrome
CI-CAN-00001612TAMExplore in graph →
- NCIt
- C82339
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Hematologic Malignancy
CI-CAN-00001612TAMExplore in graph →
Data completeness2 / 7 dimensions
Computed from entity_counters.completeness · refreshed after each connector run
Definition
A myeloid proliferation occurring in newborns with Down syndrome. It is clinically and morphologically indistinguishable from acute myeloid leukemia and is associated with GATA1 mutations. The blasts display morphologic and immunophenotypic features of megakaryocytic lineage. In the majority of patients the myeloid proliferation undergoes spontaneous remission.
Data updated 22 days agoSource updated 26.08e
Taxonomy
Several hierarchies coexist; edges are listed per hierarchy type with their source.
Parents
Children (0)
Leaf node — no children.
Anatomy
Data updated 11 hours agoSource updated unknowncounters aggregate over descendants
Names
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Key figures
Each figure carries its unit, period and source; ranks link to "Why this rank?".
Data updated 11 hours agoSource updated unknownregistry figures: cdc-uscs · latest year available per metric · counters aggregate over descendants