Gastrointestinal Stromal Tumor — Genomics

Gastrointestinal Stromal Tumor — Genomics · CancerIndex

Genomics

Gene alteration frequencies by cohort

3 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.

Gastrointestinal Stromal Tumor (MSK 2025) gist_msk_2025

183 cases with simple somatic mutation data · 183 cases total · 2026-01-20 · mapped to Gastrointestinal Stromal Tumor EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	KIT	Ssm	174	183	95.1%	cbioportal
2	CSDE1	Ssm	26	179	14.5%	cbioportal
3	SETD2	Ssm	21	183	11.5%	cbioportal
4	TP53	Ssm	20	183	10.9%	cbioportal
5	RB1	Ssm	18	183	9.8%	cbioportal
6	FAT1	Ssm	15	183	8.2%	cbioportal
9	ERCC2	Ssm	13	182	7.1%	cbioportal
8	ANKRD11

Data updated 22 days agoSource updated 2026-01-20

Gastrointestinal Stromal Tumor (MSK, NPJ Precis Oncol 2023) gist_msk_2022MSK

499 cases with simple somatic mutation data · 499 cases total · 2026-01-07 · mapped to Gastrointestinal Stromal Tumor EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	KIT

Gastrointestinal Stromal Tumors (MSK, Clin Cancer Res 2023) gist_msk_2023MSK

469 cases with simple somatic mutation data · 469 cases total · 2026-01-07 · mapped to Gastrointestinal Stromal Tumor EXACT_IDENTIFIER

cbioportalObserved30 genes · frequency = affected / profiled, as published by the cohort.

#	Gene	Alteration	Affected (n)	Profiled (n)	Frequency (%)	Source
1	KIT

Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.