Gene
TRAF2
TNF receptor associated factor 2
Explore in graph →CI-GENE-00036105HGNC:12032 ENSG00000127191 NCBI 7186 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (13)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Gastrointestinal Stromal Tumor (MSK 2025) gist_msk_2025 | Gastrointestinal Stromal Tumor | Ssm | 10 | 183 | 5.5% | 27 | cbioportal |
| Disparities in metastatic colorectal cancer between Africans and Americans (MSK, 2020) crc_nigerian_2020 | Colorectal Adenocarcinoma | Ssm | 3 | 55 | 5.5% | 176 | cbioportal |
| Breast Invasive Lobular Carcinoma (MSK, NPJ Precis Oncol 2024) ilc_msk_2023 | unmapped | Ssm | 1 | 23 | 4.3% | 57 | cbioportal |
| Pancreatic Neuroendocrine Tumors (MSK, 2023) panet_msk_erc_2023 | unmapped | Ssm | 2 | 62 | 3.2% | 107 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.