Hematologic Malignancy
Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type
CI-CAN-00009257Explore in graph →
Hematologic9 active trials1 evidence items
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Hematologic Malignancy
CI-CAN-00009257Explore in graph →
Data completeness3 / 7 dimensions
Computed from entity_counters.completeness · refreshed after each connector run
Definition
A biologic subset of diffuse large B-cell lymphomas with a unique molecular signature or expression profile. It represents approximately 50% of diffuse large B-cell lymphomas, and is characterized by the expression of CD10, BCL-6, A-myb, and LMO2 genes, BCL-2 translocation, and c-REL amplification. Morphologically, the vast majority of these lymphomas are centroblastic and a small minority are immunoblastic (ratio20:1). Patients with this type of diffuse large B-cell lymphoma have a more favorable outcome, with a 5-year survival rate of 60% and a median survival of 10 years.
Data updated 22 days agoSource updated 26.08e
Taxonomy
Several hierarchies coexist; edges are listed per hierarchy type with their source.
Parents
Children (0)
Leaf node — no children.
Anatomy
Data updated 8 minutes agoSource updated unknowncounters aggregate over descendants
Names
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Key figures
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Data updated 8 minutes agoSource updated unknownregistry figures: cdc-uscs · latest year available per metric · counters aggregate over descendants