Histology
Carcinoma of Unknown Primary
CI-CAN-00002109Explore in graph →
4,151 active trials54 approved drugs532 evidence items
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Histology
CI-CAN-00002109Explore in graph →
Genomics
198 cohorts mapped to this entity or its descendants. Each frequency is affected / profiled within one cohort; cohorts are shown separately because case selection, sequencing depth and definitions differ. By default the cohort with the most cases profiled is shown.
62 cases with simple somatic mutation data · 62 cases total · 2026-01-16 · mapped to Unclassified Renal Cell Carcinoma EXACT_IDENTIFIER
| # | Gene | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Source |
|---|---|---|---|---|---|---|
| 1 | NF2 |
Cohorts mapped to a descendant (e.g. a subtype) are included because their cases belong to this entity by definition; the mapping and its match type are shown per cohort.
| Ssm |
| 11 |
| 62 |
| 17.7% |
| cbioportal |
| 2 | SETD2 | Ssm | 11 | 62 | 17.7% | cbioportal |
| 3 | BAP1 | Ssm | 8 | 62 | 12.9% | cbioportal |
| 4 | KMT2C | Ssm | 6 | 62 | 9.7% | cbioportal |
| 5 | MTOR | Ssm | 5 | 62 | 8.1% | cbioportal |
| 8 | TSC1 | Ssm | 4 | 62 | 6.5% | cbioportal |
| 7 | PTEN | Ssm | 4 | 62 | 6.5% | cbioportal |
| 6 | ATRX | Ssm | 4 | 62 | 6.5% | cbioportal |
| 9 | DNMT3A | Ssm | 3 | 62 | 4.8% | cbioportal |
| 11 | KLF6 | Ssm | 3 | 62 | 4.8% | cbioportal |
| 10 | FH | Ssm | 3 | 62 | 4.8% | cbioportal |
| 16 | TSC2 | Ssm | 3 | 62 | 4.8% | cbioportal |
| 14 | SMARCB1 | Ssm | 3 | 62 | 4.8% | cbioportal |
| 15 | TP53 | Ssm | 3 | 62 | 4.8% | cbioportal |
| 12 | KMT2D | Ssm | 3 | 62 | 4.8% | cbioportal |
| 13 | NOTCH2 | Ssm | 3 | 62 | 4.8% | cbioportal |
| 19 | GNAS | Ssm | 2 | 62 | 3.2% | cbioportal |
| 18 | EPHA6 | Ssm | 2 | 62 | 3.2% | cbioportal |
| 24 | PBRM1 | Ssm | 2 | 62 | 3.2% | cbioportal |
| 21 | KDM6A | Ssm | 2 | 62 | 3.2% | cbioportal |
| 17 | CHEK2 | Ssm | 2 | 62 | 3.2% | cbioportal |
| 25 | PRKN | Ssm | 2 | 62 | 3.2% | cbioportal |
| 22 | KMT2A | Ssm | 2 | 62 | 3.2% | cbioportal |
| 26 | RICTOR | Ssm | 2 | 62 | 3.2% | cbioportal |
| 27 | RPTOR | Ssm | 2 | 62 | 3.2% | cbioportal |
| 23 | MLST8 | Ssm | 2 | 62 | 3.2% | cbioportal |
| 28 | SUFU | Ssm | 2 | 62 | 3.2% | cbioportal |
| 20 | IRS1 | Ssm | 2 | 62 | 3.2% | cbioportal |
| 57 | MET | Ssm | 1 | 62 | 1.6% | cbioportal |
| 58 | MITF | Ssm | 1 | 62 | 1.6% | cbioportal |
Data updated 22 days agoSource updated 2026-01-16