Gene
KLF6
KLF transcription factor 6
Explore in graph →CI-GENE-00007001HGNC:2235 ENSG00000067082 NCBI 1316 Approved
Curated evidence
Clinical evidence (0)
CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.
Data not yet available
No curated evidence item involves this gene yet.
Cohorts
Alteration frequency by cohort (6)
Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.
cbioportalProvenance
- Source
- cBioPortal for Cancer Genomics (public studies)
- Dataset
- cBioPortal mutated genes by study
- Version
- cbioportal-2026-09-01
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- cohort
- License
- ODC Open Database License (ODC-ODbL) unless otherwise noted per study; attribution to the original studies required
- PMID
- 27713405
- Run
- ING-CBIOPORTAL-20260908-000001
| Cohort | Mapped cancer | Alteration | Affected (n) | Profiled (n) | Frequency (%) | Rank in cohort | Source |
|---|---|---|---|---|---|---|---|
| Unclassified Renal Cell Carcinoma (MSK, Nature 2016) urcc_mskcc_2016 | Unclassified Renal Cell Carcinoma | Ssm | 3 | 62 | 4.8% | 11 | cbioportal |
| Metastatic Melanoma (MSK, JCO Precis Oncol 2017) skcm_vanderbilt_mskcc_2015 | Cutaneous Melanoma | Ssm | 2 | 66 | 3% | 113 | cbioportal |
| Glioblastoma (TCGA, Nature 2008) gbm_tcga_pub | Diffuse Glioma | Ssm | 2 | 91 | 2.2% | 45 | cbioportal |
| Bladder Cancer (MSK, Eur Urol 2014) blca_mskcc_solit_2014 | Bladder Urothelial Carcinoma | Ssm | 2 | 109 | 1.8% | 155 | cbioportal |
Literature
Linked publications (0)
Data not yet available
No publication linked to this gene yet.