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CancerIndex

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Anaplastic Ependymoma · CancerIndex

Cancers
Neoplasm
Neoplasm by Special Category
Malignant Neoplasm
Anaplastic Malignant Neoplasm
Anaplastic Ependymoma

Subtype

Anaplastic Ependymoma

CI-CAN-00000441Explore in graph →

4 active trials1 evidence items

NCIt: C4049
OncoTree: APE
DOID: 5889
UMLS CUI: C0280788

Overview
Statistics
Survival
Genomics
Variants & evidence1
Drugs1
Trials31
Research
Rankings
Sources & provenance

Data completeness3 / 7 dimensions

Epidemiology (no data yet)
Survival (no data yet)
Trials (data present)
Literature (data present)
Genomics (no data yet)
Evidence (data present)
Therapies (no data yet)

Computed from entity_counters.completeness · refreshed after each connector run

Definition

What this entity is

A WHO grade 3 malignant glioma of ependymal origin with accelerated growth and an unfavorable clinical outcome, particularly in children. It is characterized by high mitotic activity, often accompanied by microvascular proliferation and pseudo-palisading necrosis. (Adapted from WHO)

Definition text as published by ncit-evsProvenance

Source: NCI Thesaurus (NCIt)
Dataset: NCI Thesaurus
Version: 26.08e
Retrieved: Sep 8, 2026
Layer: raw (as published)
Evidence: expert curation
License: CC BY 4.0
Run: ING-NCITEVS-20260908-000001

Open at source Curated

Data updated 22 days agoSource updated 26.08e

Taxonomy

Position in the hierarchies

Several hierarchies coexist; edges are listed per hierarchy type with their source.

Parents

ncit

Anaplastic Malignant NeoplasmCancer Family
Ependymal TumorSubtype
WHO Grade 3 GliomaSubtype

oncotree

Ependymal TumorSubtype

Children (2)

ncit

Adult Anaplastic Ependymoma
Childhood Anaplastic Ependymoma

Anatomy

Anatomical sites

Nervous SystemC3268

Record

Identity

CancerIndex ID: CI-CAN-00000441
Entity type: Subtype
Malignant: Yes
Solid / hematologic: Solid tumor
Pediatric relevant: Not flagged
Rare cancer: Unknown (no incidence data yet)
Hierarchy depth: 4
Classification version: 26.08e
Semantic types: Neoplastic Process
Status: Active
Record updated: 2026-09-08

Coverage

Data completeness

Trials (all / active): 31 / 4

Publications (all / 5y)

477 / 90

Evidence items

1

Genes / variants

1 / 1

Drugs (any / approved)

1 / 0

Genomic cohorts

0

Epidemiology / survival obs.

0 / 0

Data updated 7 hours agoSource updated unknowncounters aggregate over descendants

Names

Synonyms (13)

Anaplastic Ependymal Neoplasmsynonym · NCIt
Anaplastic Ependymal Tumorsynonym · NCIt
Anaplastic Ependymomasynonym · OncoTree
Ependymoma, anaplasticsynonym · NCIt
Ependymoma with Anaplasiasynonym · NCIt
Malignant Ependymomasynonym · NCIt
Undifferentiated Ependymal Neoplasmsynonym · NCIt
Undifferentiated Ependymal Tumorsynonym · NCIt
Undifferentiated Ependymomasynonym · NCIt
WHO Grade 3 Ependymal Neoplasmsynonym · NCIt
WHO Grade 3 Ependymal Tumorsynonym · NCIt
WHO Grade III Ependymal Neoplasmsynonym · NCIt
WHO Grade III Ependymal Tumorsynonym · NCIt

CancerIndex is a research and information platform. It does not diagnose and does not recommend treatment.

Key figures

At a glance

Each figure carries its unit, period and source; ranks link to "Why this rank?".

US deaths18,523countUnited States · 2024 · both sexes · all agescdc-wonderObservedrank #9 of 31 (USA · both sexes · all ages · 2024 · top-level cancers)figures shown for Malignant Central Nervous System Neoplasm (registry level) — open Malignant Central Nervous System Neoplasm
US new cases22,882countUnited States · 2023 · both sexes · all agescdc-uscsObservedrank #17 of 32 (USA · both sexes · all ages · 2023 · top-level cancers)figures shown for Malignant Central Nervous System Neoplasm (registry level) — open Malignant Central Nervous System Neoplasm
US age-standardized mortality4.4per 100,000United States · 2024 · both sexes · all ages · 2000 U.S. Std. Populationcdc-wonderObservedrank #8 of 23 (USA · both sexes · all ages · 2024 · top-level cancers)figures shown for Malignant Central Nervous System Neoplasm (registry level) — open Malignant Central Nervous System Neoplasm
Active trials4countcurrent registry status · entity + descendantsclinicaltrialsComputedrank #795 of 1,654 (World · both sexes · all ages · latest · all malignant entities)
Recruiting trials3countstatus RECRUITING · entity + descendantsclinicaltrialsComputedrank #677 of 1,284 (World · both sexes · all ages · latest · all malignant entities)
Curated evidence items1countaccepted CIViC items · entity + descendantscivicComputedrank #392 of 492 (World · both sexes · all ages · latest · all malignant entities)
Publications, last 12 months11countPubMed records · stored query · 12-month windowpubmedComputedrank #946 of 2,294 (World · both sexes · all ages · latest · all malignant entities)
Genomic cohorts0countopen GDC projects · entity + descendantsgdcComputednot in a current ranking snapshot

Data updated 7 hours agoSource updated unknownregistry figures: cdc-uscs · latest year available per metric · counters aggregate over descendants