Loading clinical trials…
Loading clinical trials…
Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
1,672 stopped studies mapped to Malignant Reproductive System Neoplasm and descendants · 89% state a reason
Over the 1,672 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT02564549 | MRI-Based Active Surveillance to Avoid the Risks of Serial Biopsies in Men With Low-Risk… | N/A | terminated | Sep 30, 2015 | Virginia Commonwealth University | Study halted prematurely and will not resume | Other (stated, no rule matched) |
| NCT02232672 | Choline PET/CT vs. MeAIB PET/CT in Prostate Cancer | N/A | withdrawn | Sep 5, 2014 | Odense University Hospital | not stated | Not stated |
| NCT03032614 | Combination of Carboplatin, Eribulin and Veliparib in Stage IV Cancer Patients | Phase 2 | withdrawn | Jan 26, 2017 | The University of Texas Health Science Center at San Antonio | Lack of funding | Funding |
| NCT00480857 | Salvage Radiation Therapy and Taxotere for PSA Failure After Radical Prostatectomy | Phase 2 | terminated | May 31, 2007 | University of Michigan Rogel Cancer Center | Lack of funding. | Funding |
| NCT02278783 | Phase 2 Trial of Regorafenib in Patients With Recurrent Ovarian, Primary Peritoneal and… | Phase 2 | terminated | Oct 30, 2014 | University of Utah | Slow Accrual | Enrollment / accrual |
| NCT03007771 | Magnetic Resonance-guided High-Intensity Focused Ultrasound (MR-HIFU) Used for Mild… | Phase 1 | withdrawn | Jan 2, 2017 | Washington University School of Medicine | Decision was made to not go forward with the study | Other (stated, no rule matched) |
| NCT03173807 | Prostate Nutrition and Exercise STudy (ProNEST)(ProNEST) | N/A | withdrawn | Jun 2, 2017 | University of Pittsburgh | Unable to find adequate funding | Funding |
| NCT00531687 | Trial of Paclitaxel, Gemcitabine and Cisplatin in Patients With Relapsing Germ Cell Cancer | Phase 2 | terminated | Sep 19, 2007 | Rigshospitalet, Denmark | slow accrual | Enrollment / accrual |
| NCT00003525 | Antineoplaston Therapy in Treating Patients With Stage IV Cancer of the Cervix and/or… | Phase 2 | terminated | Jan 27, 2003 | Burzynski Research Institute | slow accrual | Enrollment / accrual |
| NCT01145508 | Docetaxel and Prednisone With or Without Vaccine Therapy in Treating Patients With… | Phase 2 | terminated | Jun 16, 2010 | National Cancer Institute (NCI) | Poor accrual | Enrollment / accrual |
| NCT02454595 | Registry to Measure the Impact of Adding Genomic Testing | — | terminated | May 27, 2015 | Myriad Genetic Laboratories, Inc. | lack of enrollment | Enrollment / accrual |
| NCT01866423 | Orteronel in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer | Phase 2 | terminated | May 31, 2013 | University of Southern California | Not progressing toward scientific goals | Other (stated, no rule matched) |
| NCT00354601 | Docetaxel and Capecitabine in Treating Patients With Recurrent or Persistent Ovarian… | Phase 2 | terminated | Jul 20, 2006 | Wake Forest University Health Sciences | funding withdrawn | Funding |
| NCT01677845 | Hypo-Fractionated Radiation Therapy for Localized Prostate Cancer | Phase 1 | terminated | Sep 3, 2012 | NYU Langone Health | PI no longer with the institution | Other (stated, no rule matched) |
| NCT00600210 | Neoadjuvant Bevacizumab and Carboplatin Followed by Concurrent Bevacizumab, Carboplatin… | Phase 2 | withdrawn | Jan 24, 2008 | Leo W. Jenkins Cancer Center | low patient accrual | Enrollment / accrual |
| NCT02810886 | Prospective Evaluation of 68Ga-PSMA PET-CT for Recurrence Detection of Prostate Cancer…(ProsPERo) | Phase 2 | withdrawn | Jun 23, 2016 | Jules Bordet Institute | Recent publications demonstrating the clinical interest in performing 68Ga-PSMA for recurrence… | Other (stated, no rule matched) |
| NCT01991210 | A Study of DNIB0600A in Comparison With Pegylated Liposomal Doxorubicin (PLD) in… | Phase 2 | terminated | Nov 25, 2013 | Genentech, Inc. | The primary objective of PFS did not meet pre-specified criteria. | Other (stated, no rule matched) |
| NCT00408967 | Determine if Either of 2 Doses of Study Drug Given With a Low-dose of Cyclophosphamide… | Phase 2 | withdrawn | Dec 8, 2006 | EMD Serono | Th trial got cancelled and no subjects signed informed consent form (ICF); study design not… | Other (stated, no rule matched) |
| NCT01842789 | Post Market Evaluation of Acessa With TAG(TAG) | N/A | terminated | Apr 30, 2013 | Acessa Health, Inc. | Results to date adequately demonstrated user preference and recovery time. Time to target (Part II)… | Other (stated, no rule matched) |
| NCT00004221 | Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients… | Phase 2 | terminated | Aug 25, 2003 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00898833 | Plasma and Urine Samples From Patients With Hormone-Refractory Prostate Cancer Enrolled… | — | terminated | May 12, 2009 | Alliance for Clinical Trials in Oncology | The proposed work could not be completed. | Other (stated, no rule matched) |
| NCT02223975 | Evaluation of the Role of Vibrational Spectroscopy in the Assessment of Vulval Disease(Vulval VS) | — | suspended | Aug 22, 2014 | Gloucestershire Hospitals NHS Foundation Trust | Study suspended pending further funding | Funding |
| NCT00900081 | Cyclooxygenase-2 Expression in Tissue Samples From Patients With a Normal Cervix,… | — | withdrawn | May 12, 2009 | Wake Forest University Health Sciences | no accrual, PI left institution | Investigator |
| NCT01419795 | Lenalidomide With or Without Rituximab in Treating Patients With Progressive or Relapsed… | Phase 2 | terminated | Aug 18, 2011 | Fred Hutchinson Cancer Center | Low accrual | Enrollment / accrual |
| NCT02307552 | Transurethral Ultrasonic Imaging For Detection and Classification of Prostate Cancer | N/A | terminated | Dec 4, 2014 | University of California, Irvine | The probe could not be anchored in place and would rotate about its axis, thus comparison was… | Other (stated, no rule matched) |
| NCT01641497 | Phase III Study Comparing 3D Conformal Radiotherapy and Conformal Radiotherapy IMRT to…(TOMOGYN) | N/A | terminated | Jul 16, 2012 | Centre Oscar Lambret | Recruitment difficulties | Enrollment / accrual |
| NCT02093871 | A Phase 1 Trial of Perfusion Induced Systemic Hyperthermia (PISH) Over Multiple Cycles…(PISH-2) | Phase 1 | suspended | Mar 21, 2014 | ThermalCore Inc | not stated | Not stated |
| NCT02042053 | PET/MR Assessment of Sipuleucel T Treatment for Metastatic Castration Resistant Prostate… | N/A | terminated | Jan 22, 2014 | NYU Langone Health | Due to PI leaving the institution | Other (stated, no rule matched) |
| NCT00551265 | Oregovomab With or Without Cyclophosphamide in Treating Patients With Stage III or Stage… | N/A | withdrawn | Oct 30, 2007 | Gynecologic Oncology Group | not stated | Not stated |
| NCT00003622 | Vinorelbine Plus Paclitaxel in Treating Patients With Metastatic Prostate Cancer That Is… | Phase 2 | withdrawn | May 3, 2004 | James Ahlgren | No recruitment | Enrollment / accrual |
| NCT00003865 | Toremifene in Treating Patients With Ovarian Cancer | Phase 2 | withdrawn | Jan 27, 2003 | George Washington University | not stated | Not stated |
| NCT01754519 | Radiation Therapy in Treating Post-Menopausal Women With Early Stage Breast Cancer… | Phase 2 | terminated | Dec 21, 2012 | Roswell Park Cancer Institute | IDE not submitted | Other (stated, no rule matched) |
| NCT03211052 | A Study of Neoadjuvant TAK-700 and Leuprorelin Acetate Followed by Surgery Versus Surgery…(NEPTUNE) | Phase 2 | terminated | Jul 7, 2017 | Centre of Experimental Medicine | IMP no longer available | Other (stated, no rule matched) |
| NCT01176500 | A Pilot, Open-label Study of 18F-Fluciclatide PET/CT Imaging in the Evaluation of… | Phase 1 / Phase 2 | withdrawn | Aug 6, 2010 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01386502 | CT-011 and p53 Genetic Vaccine for Advanced Solid Tumors | Phase 1 | withdrawn | Jul 1, 2011 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT00536991 | Calcitriol in Combination With Ketoconazole and Therapeutic Hydrocortisone in Treating… | Phase 1 / Phase 2 | terminated | Sep 28, 2007 | Roswell Park Cancer Institute | difficult to recruit | Enrollment / accrual |
| NCT01184053 | Trisenox® in Women With Metastatic Endometrial Cancer(NRR) | Phase 2 | terminated | Aug 18, 2010 | UNC Lineberger Comprehensive Cancer Center | Accrual was very low. No subject had been enrolled in a year. | Enrollment / accrual |
| NCT00084864 | Calcitriol and Dexamethasone Before Radical Prostatectomy in Treating Patients With… | Phase 2 | terminated | Jun 11, 2004 | Roswell Park Cancer Institute | sample size is too small to draw a conclusion | Other (stated, no rule matched) |
| NCT01558492 | Carboplatin and Paclitaxel in Patients With Metastatic, Castrate-Resistant Prostate Cancer | Phase 2 | terminated | Mar 20, 2012 | Weill Medical College of Cornell University | Poor accrual | Enrollment / accrual |
| NCT01338012 | Sipuleucel-T in Metastatic Castrate Resistant Prostate Cancer(mCRPC) | Phase 2 | terminated | Apr 19, 2011 | Dendreon | Administrative reasons. | Other (stated, no rule matched) |
| NCT01972516 | Tivozanib As Maintenance Therapy In GYN | Phase 2 | terminated | Oct 30, 2013 | Dana-Farber Cancer Institute | due to slow accrual | Enrollment / accrual |
| NCT01461772 | Efficacy and Safety Study of Concurrent Chemoradiation Therapy to Treat Locally Advanced… | Phase 3 | terminated | Oct 28, 2011 | Asan Medical Center | Because of very slow rate of enrollement | Enrollment / accrual |
| NCT01642732 | Study of Everolimus Added to Combined Hormonal and Radiation Therapy for High Risk… | Phase 1 | terminated | Jul 17, 2012 | University of Michigan Rogel Cancer Center | Lack of accrual and funding expires in June, 2014. | Enrollment / accrual |
| NCT01681368 | Birinapant for Advanced Ovarian, Fallopian Tube, and Peritoneal Cancer | Phase 2 | terminated | Sep 7, 2012 | National Cancer Institute (NCI) | Accrual was terminated for lack of a clinical benefit. | Enrollment / accrual |
| NCT02429804 | NaF/FDG PET/MRI in Measuring Response to Radium Ra 223 Dichloride in Patients With… | Phase 1 | terminated | Apr 29, 2015 | Stanford University | Accrual factor | Enrollment / accrual |
| NCT00088881 | Rituximab, Combination Chemotherapy, and 90-Yttrium Ibritumomab Tiuxetan for Patients… | Phase 2 | terminated | Aug 5, 2004 | National Cancer Institute (NCI) | not stated | Not stated |
| NCT01385293 | BKM120 in Metastatic Castration-resistant Prostate Cancer | Phase 2 | terminated | Jun 30, 2011 | Andrew J. Armstrong, MD | The trial was stopped at the first stage due to futility | Efficacy / futility |
| NCT01940237 | A Pilot Trial of Interpersonal Psychotherapy for the Treatment of Depression in Patients… | N/A | terminated | Sep 12, 2013 | New York State Psychiatric Institute | Low recruitment | Enrollment / accrual |
| NCT01215032 | Metformin in Castration-Resistant Prostate Cancer | Phase 2 | terminated | Oct 5, 2010 | Massachusetts General Hospital | slow accrual, competing clinical trials | Enrollment / accrual |
| NCT02417753 | AZD9150, a STAT3 Antisense Oligonucleotide, in People With Malignant Ascites | Phase 2 | terminated | Apr 16, 2015 | National Cancer Institute (NCI) | Study was closed because we could not find these types of patients. | Other (stated, no rule matched) |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated 24 days agoSource updated Oct 19, 2017source: clinicaltrials