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Clinical trials · failure tracking
Oncology studies whose overall status is TERMINATED, WITHDRAWN or SUSPENDED on ClinicalTrials.gov, with the stop reason exactly as the registrant posted it. A category is attached only when an explicit keyword rule matches the text; CancerIndex never infers why a study stopped.
1,672 stopped studies mapped to Malignant Reproductive System Neoplasm and descendants · 89% state a reason
Over the 1,672 studies matching the cancer, status and year filters (the category filter does not change this chart). Each study is counted once, in the first matching category; greyed bars are studies whose text matched no rule or was empty.
Computedrules ci-stop-reasons-v1 · keyword matching only
A category is assigned when one of its keywords appears in the posted text (case-insensitive, whole words). Rules are tested in this order and the first match wins; every match is kept in the API (reasonMatches).
| NCT | Title | Phase | Status | First posted | Lead sponsor | Why stopped (as posted) | Category |
|---|---|---|---|---|---|---|---|
| NCT05932212 | AK104 for Recurrent or Metastatic Vulvar Cancer | Phase 2 | terminated | Jul 6, 2023 | Akeso | Sponsor decision | Sponsor / business decision |
| NCT03108495 | Study of LN-145, Autologous Tumor Infiltrating Lymphocytes in the Treatment of Patients… | Phase 2 | terminated | Apr 11, 2017 | Iovance Biotherapeutics, Inc. | After reviewing available safety and efficacy data to date, Iovance concluded the study reached the… | Safety / toxicity |
| NCT04071236 | Radiation Medication (Radium-223 Dichloride) Versus Radium-223 Dichloride Plus Radiation… | Phase 1 / Phase 2 | suspended | Aug 28, 2019 | National Cancer Institute (NCI) | Other - To assess the study's feasibility. | Other (stated, no rule matched) |
| NCT06144619 | Non-Invasive Biomarkers in Prostate Cancer Disease Management | — | suspended | Nov 22, 2023 | H. Lee Moffitt Cancer Center and Research Institute | Funding unavailable | Funding |
| NCT06714617 | Evaluate BL-M17D1 in Patients w/HER2-Expressing/Mutant Advanced or Metastatic Solid Tumors | Phase 1 | terminated | Dec 3, 2024 | SystImmune Inc. | The decision is based only on the Sponsor's internal portfolio prioritization and resource… | Safety / toxicity |
| NCT04615845 | A Phase 1 Study of Autologous Dendritic Cell Immunotherapy in Patients With mCRPC | Phase 1 | terminated | Nov 4, 2020 | Pharmicell Co., Ltd. | Difficulties in patient recruitment. | Enrollment / accrual |
| NCT04614051 | A Phase 1 Study of Cellgram-DC in Patients With Advanced or Recurrent Epithelial Ovarian… | Phase 1 | terminated | Nov 3, 2020 | Pharmicell Co., Ltd. | Difficulties in patient recruitment. | Enrollment / accrual |
| NCT04808427 | Pilot Study to Investigate Magnetic Resonance (MR) Image Guided Focal Therapy in Prostate… | N/A | suspended | Mar 22, 2021 | National Cancer Institute (NCI) | On hold pending consideration of an amendment to increase recruitment. | Enrollment / accrual |
| NCT03634267 | MRI-Guided Brachytherapy in Treating Participants With HPV-Associated Stage IB2-IVA… | Phase 1 | terminated | Aug 16, 2018 | M.D. Anderson Cancer Center | PI Request | Other (stated, no rule matched) |
| NCT04286386 | Development and Evaluation of a Quantitative HP MRI for Clinical Prostate Cancer Exam | — | withdrawn | Feb 27, 2020 | M.D. Anderson Cancer Center | No Participants Enrolled | Enrollment / accrual |
| NCT05080946 | Using Aspirin to Improve Immunological Features of Ovarian Tumors | Early Phase 1 | suspended | Oct 18, 2021 | H. Lee Moffitt Cancer Center and Research Institute | Study drug is expiring. Will reopen when new drug is received. | Other (stated, no rule matched) |
| NCT03694483 | Prostasomes as Diagnostic Tool for Prostate Cancer Detection | — | suspended | Oct 3, 2018 | Hackensack Meridian Health | Staffing changes, pending funding renewal | Funding |
| NCT07181720 | CD70-Targeted CAR-T Therapy in CD70-Positive Advanced Solid Tumors | Phase 1 | suspended | Sep 18, 2025 | Chongqing Precision Biotech Co., Ltd | Sponsor stopped the study. | Other (stated, no rule matched) |
| NCT04683653 | Study of Pelvic Hypofractionated Radiotherapy in Endometrial Cancer | Phase 1 / Phase 2 | suspended | Dec 24, 2020 | University of Chicago | Enrollment Goal Met | Enrollment / accrual |
| NCT04544735 | Improving Women's Function After Pelvic Radiation | N/A | suspended | Sep 10, 2020 | Duke University | Study is suspended due to lack of funds. Will resume as soon as funding is secured. | Funding |
| NCT04315233 | Ribociclib&Belinostat In Patients w Metastatic Triple Neg Breast Cancer & Recurrent…(CHARGE) | Phase 1 | terminated | Mar 19, 2020 | University of Utah | No accrual in one year | Enrollment / accrual |
| NCT05700903 | Contributions to Hypertension With Androgen Deprivation Therapy(ARCH) | Phase 4 | terminated | Jan 26, 2023 | University of Colorado, Denver | Study completed | Other (stated, no rule matched) |
| NCT05458960 | Impact of Basic Needs Assessment and Support to Improve Colposcopy Show Rate(BASICS) | N/A | terminated | Jul 14, 2022 | Washington University School of Medicine | Staffing issues | Other (stated, no rule matched) |
| NCT06804785 | Hybrid Intelligence for Trustable Diagnosis and Patient Management of Prostate Cancer…(HIT-PIRADS) | — | withdrawn | Feb 3, 2025 | Northwestern University | Due to funding issues the study did not move forward with prospective enrollment | Enrollment / accrual |
| NCT06982222 | Testing the Safety of the Anti-cancer Drug, Sn-117m-DTPA, for Advanced Cancers That Have… | Phase 1 | withdrawn | May 21, 2025 | National Cancer Institute (NCI) | Other - Protocol moved to Withdrawn | Other (stated, no rule matched) |
| NCT03442556 | Docetaxel, Carboplatin, and Rucaparib Camsylate in Treating Patients With Metastatic… | Phase 2 | terminated | Feb 22, 2018 | University of Washington | Terminated due to insufficient funding | Funding |
| NCT04631601 | Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer… | Phase 1 / Phase 2 | terminated | Nov 17, 2020 | Amgen | Amgen made a business decision to discontinue all AMG 160 clinical trials. This decision is not… | Safety / toxicity |
| NCT03184753 | Genetically Modified T Cells Against Ovarian Cancer | Phase 1 / Phase 2 | terminated | Jun 14, 2017 | Shenzhen Geno-Immune Medical Institute | not stated | Not stated |
| NCT03356795 | Intervention of CAR-T Against Cervical Cancer | Phase 1 / Phase 2 | terminated | Nov 29, 2017 | Shenzhen Geno-Immune Medical Institute | not stated | Not stated |
| NCT03362606 | Engineered Immune Effectors Against Ovarian Cancer | Phase 1 / Phase 2 | terminated | Dec 5, 2017 | Shenzhen Geno-Immune Medical Institute | not stated | Not stated |
| NCT03362619 | Engineered Immune Effectors Against Cervical Cancer | Phase 1 / Phase 2 | terminated | Dec 5, 2017 | Shenzhen Geno-Immune Medical Institute | not stated | Not stated |
| NCT04019327 | A Study of the Drugs Talazoparib and Temozolomide in Prostate Cancer | Phase 1 / Phase 2 | terminated | Jul 15, 2019 | Memorial Sloan Kettering Cancer Center | Study terminated by sponsor | Other (stated, no rule matched) |
| NCT06200103 | Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate… | Phase 2 | suspended | Jan 10, 2024 | Mayo Clinic | Pending additional funding. | Funding |
| NCT06315491 | A Study of CBX 12 in Subjects With Platinum Resistant or Refractory Ovarian Cancer | Phase 2 | terminated | Mar 18, 2024 | Cybrexa Therapeutics | Limited clinical activity | Other (stated, no rule matched) |
| NCT00126230 | Trial of Docetaxel-samarium in Patients With Hormone-refractory Advanced Prostate Cancer | Phase 2 | terminated | Aug 3, 2005 | Gustave Roussy, Cancer Campus, Grand Paris | not stated | Not stated |
| NCT05827614 | Study of the CHK1 Inhibitor BBI-355, an ecDNA-directed Therapy (ecDTx), and the RNR…(POTENTIATE) | Phase 1 | terminated | Apr 25, 2023 | Boundless Bio, Inc. | Decision was made to halt the study based on overall clinical experience and market considerations.… | Safety / toxicity |
| NCT07090174 | CASCADE: Testing for Safety and Immune Effects of PDS0101, an Anti-HPV Therapy, Among… | Phase 2 | withdrawn | Jul 29, 2025 | University of California, San Diego | Study withdrawn prior to participant enrollment due to lack of study product. | Enrollment / accrual |
| NCT04840589 | Testing the Combination of ZEN003694 and Nivolumab With or Without Ipilimumab in Solid… | Phase 1 | suspended | Apr 12, 2021 | National Cancer Institute (NCI) | Other - Pending amendment. | Other (stated, no rule matched) |
| NCT07102212 | Telemedicine-mHealth Symptom Cluster Intervention for Advanced Cancer Patients: Finding…(FOCUS) | N/A | suspended | Aug 3, 2025 | Ohio State University Comprehensive Cancer Center | pending amendment | Other (stated, no rule matched) |
| NCT07173101 | Clinical Investigation of the Effects of Semiconductor Embedded Therapeutic Garments on…(HEADBAND) | Phase 2 | terminated | Sep 15, 2025 | University of Utah | Safety Review | Safety / toxicity |
| NCT05842031 | Assessment of Patient Experience and Needs for Patients Undergoing Invasive Inguinal… | — | suspended | May 3, 2023 | M.D. Anderson Cancer Center | PI requested | Other (stated, no rule matched) |
| NCT02769962 | Trial of EP0057, a Nanoparticle Camptothecin With Olaparib in People With… | Phase 1 / Phase 2 | terminated | May 12, 2016 | National Cancer Institute (NCI) | Accrual and drug manufacturing and supply were discontinued in 2025. | Drug supply |
| NCT03987555 | Paclitaxel Therapeutic Drug Monitoring in Cancer Patients | — | suspended | Jun 17, 2019 | Wake Forest University Health Sciences | Funding | Funding |
| NCT05572684 | A Safety, Tolerability and Efficacy Study of NC410 Plus Pembrolizumab in Participants… | Phase 1 / Phase 2 | terminated | Oct 10, 2022 | NextCure, Inc. | Following completion of Phase 1b, the Sponsor decided not to initiate Part 2 of the trial. | Sponsor / business decision |
| NCT04519879 | White Button Mushroom Sup for the Reduction of PSA in Pts With Biochemically Rec or… | Phase 2 | suspended | Aug 20, 2020 | City of Hope Medical Center | 05/26/2026 DSMC: Delinquent PMT reporting. | Other (stated, no rule matched) |
| NCT04899492 | Evaluating Smoking Cessation Protocols in Cancer Patients: NRT, MI, CBT or Hypnotherapy(RESPIRE) | N/A | terminated | May 24, 2021 | Institut Cancerologie de l'Ouest | lack of patient enrolment | Enrollment / accrual |
| NCT05226507 | A Phase 1 Clinical Study of NXP800 in Subjects With Advanced Cancers and Expansion in… | Phase 1 | terminated | Feb 7, 2022 | Nuvectis Pharma, Inc. | Study terminated due to various reasons impacting the feasibility of future clinical development | Other (stated, no rule matched) |
| NCT00799110 | Vaccination of Patients With Ovarian Cancer With Dendritic Cell/Tumor Fusions With… | Phase 2 | terminated | Nov 27, 2008 | Beth Israel Deaconess Medical Center | Withdrawal of funding | Funding |
| NCT05995236 | Prostate-Specific Membrane Antigen (PSMA) Radionuclide Therapy | — | terminated | Aug 16, 2023 | Methodist Health System | So far, we have not been able to collect meaningful data for these patients which also led to our… | Other (stated, no rule matched) |
| NCT03152786 | Propranolol Hydrochloride in Treating Patients With Prostate Cancer Undergoing Surgery | Phase 2 | terminated | May 15, 2017 | Wake Forest University Health Sciences | PIs not interested in continuing with the trial. | Other (stated, no rule matched) |
| NCT04646434 | Brain and Pelvic Floor Muscle Activity of Patients Who Had or Are Undergoing… | N/A | suspended | Nov 30, 2020 | Roswell Park Cancer Institute | Protocol being updates and staff trained | Other (stated, no rule matched) |
| NCT03287271 | ROCKIF Trial: Re-sensitization of Carboplatin-resistant Ovarian Cancer With Kinase… | Phase 1 / Phase 2 | terminated | Sep 19, 2017 | Michael McHale | Due to loss of funding | Funding |
| NCT03031821 | Metformin in Patients Initiating ADT as Prevention and Intervention of Metabolic Syndrome(PRIME) | Phase 3 | terminated | Jan 26, 2017 | Canadian Urologic Oncology Group | Manufacturer discontinued the production of study drugs. | Drug supply |
| NCT04974944 | First-line Treatment With Camrelizumab + Apatinib Versus Chemotherapy + Bevacizumab in… | Phase 2 | terminated | Jul 23, 2021 | Sun Yat-Sen University Cancer Center | No superior PFS in study group among the enrolled patients. Company R\&D strategy shifted; funding… | Enrollment / accrual |
| NCT05180474 | GEN1047 for Solid Tumors - First in Human (FIH) Trial | Phase 1 / Phase 2 | terminated | Jan 6, 2022 | Genmab | The Sponsor has made a strategic decision to stop the development of GEN1047. | Sponsor / business decision |
Stop reasons are registrant-reported free text and are displayed verbatim (truncated; hover for the full text). Categories come from explicit keyword rules and are never inferred from the study design, sponsor or outcome; a study that stopped for several reasons is filed under the first rule that matched. A TERMINATED status does not imply a negative result.
Data updated yesterdaySource updated Sep 28, 2026source: clinicaltrials