Clinical trial · Interventional
Phase III Study Comparing 3D Conformal Radiotherapy and Conformal Radiotherapy IMRT to Treat Endometrial Cancer
Phase III Study Comparing 3D Conformal Radiotherapy and Conformal Radiotherapy IMRT to Treat Endometrial Cancer of 70 Years Old Women : Contribution of Oncogeriatric Evaluation to the Study of Acute Toxicity
NCT01641497CI-TRIAL-00028726TOMOGYNterminatedN/AClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Why stopped (as posted): Recruitment difficulties
Summary
Brief summary (as posted)
Comparison of radiotherapy tolerance (two types of radiotherapy) for patients over 70 years with a endometrial cancer.
Conditions
Conditions (1)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Endometrial Cancer | Malignant Endometrial Neoplasm | CURATED_BROADER | 0.80 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| 3D conformational radiation | Radiation | — | UNRESOLVED |
| IMRT | Radiation | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- 3D conformational radiotherapy
- description
- 25 \* 1.8 Gy in 5 weeks (=45 Gy). 3D conformational radiation
- interventionNames
- Radiation: 3D conformational radiation
- type
- EXPERIMENTAL
- label
- Intensity-Modulated Radiation Therapy
- description
- 25 \* 1.8 Gy in 5 weeks (=45 Gy). IMRT
- interventionNames
- Radiation: IMRT
Primary outcomes (1)
- measure
- change from baseline in acute toxicity all along the radiation
- timeFrame
- baseline, Day 5, Day 10, Day 15, Day 20, Day 25, 1 Week after end of treatment, 8 Weeks after end of treatment
Eligibility
Eligibility (as posted)
- Sex
- Female
- Minimum age
- 70 Years
Show eligibility criteria text
Inclusion Criteria: * endometrial adenocarcinoma histologically proven * post op pelvic radiotherapy * age ≥ 70 * performance status ≤ 2 * MMSE ≥ 10 * life expectancy ≥ 3 months * social security covered * signed informed consent Exclusion Criteria: * type I stade IAGI and stade IAGIII without myometer infiltration, stade IIIc2 and IV adenocarcinoma * uterine sarcoma * surgery not in accordance with recommendations of Inca * previous uncontrolled or less than 5 years prior to diagnosis cancer * cons-indication for radiotherapy * diarrhea ≥ 3 per day * pelvic lymph nodes \> 1cm not resected during staging * previous sigmoid diverticulitis, crohn disease, systemic disease, ulcerative haemorrhagic, collagenosis, infectious peritonitis * IMRT other than tomotherapy * photon energy \< 10MV * patient under guardianship
References
Publications (0)
Data not yet available
No reference posted for this study.