Knowledge graph · Gene
NOTCH3
notch receptor 3
- Identifier
- CI-GENE-00017013
- Entity page
- /gene/NOTCH3 ↗
- Edges
- 26
- Neighbours
- 9 cancers15 variants1 drugs
- Drawn
- 25 of 25 neighbours (cap 60); table lists every fetched edge
Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.
Most connectedLung Non-Small Cell Carcinoma 3,147Malignant Colorectal Neoplasm 1,866ABL1 298EGFR 276Imatinib 450Dasatinib 321
Neighbourhood
Radial view
Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.
Edges
Every edge, grouped by relationship
Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.
| Relationship | Neighbour | Direction | Evidence level | Cancer context | Support | Claim | Source | Expand |
|---|---|---|---|---|---|---|---|---|
| NOTCH3 targets …TARGETS1 of 1 | ||||||||
| ← targets | Tarextumabmonoclonal_antibody | — | INHIBITOR | — | 1 | Curated | chembl | graph → |
| NOTCH3 has variant …HAS_VARIANTderived15 of 16show all (up to 200) | ||||||||
| → has variant | NM_000435.3(NOTCH3):c.146G>T (p.Cys49Phe)SNV | |||||||