Porfimer

Identifier: CI-DRUG-00000693
Entity page: /drug/porfimer ↗
Edges: 57

Neighbours: 25 cancers10 trials7 approvals
Drawn: 42 of 42 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Porfimer approved for …APPROVED_FOR9 of 7
→ approved for	Lung Non-Small Cell Carcinomasubtype	supports	FDA ORIG	Lung Non-Small Cell Carcinoma	1	Regulatory	openfda	graph →
→ approved for	Malignant Esophageal Neoplasmcancer	supports	FDA ORIG

Porfimer investigated in trials for …INVESTIGATED_IN_TRIALSderived25 of 25show fewer
→ investigated in trials for	Lung Non-Small Cell Carcinomasubtype 6 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Lung Non-Small Cell Carcinoma	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Lung Neoplasm 4 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Lung Neoplasm	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Extrahepatic Bile Duct Neoplasm 3 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Extrahepatic Bile Duct Neoplasm	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Gallbladder Neoplasm 3 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Gallbladder Neoplasm	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Head and Neck Neoplasm 3 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Head and Neck Neoplasm	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Mesothelioma 3 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Mesothelioma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Lung Neoplasm 2 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Lung Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Pancreatic Neoplasm 2 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Pancreatic Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Head and Neck Carcinoma 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Head and Neck Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Hepatocellular Carcinoma 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Hepatocellular Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Laryngeal Squamous Cell Carcinoma 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Laryngeal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Laryngeal Verrucous Carcinoma 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Laryngeal Verrucous Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Lip and Oral Cavity Squamous Cell Carcinoma 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Lip and Oral Cavity Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Lung Carcinoma 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Lung Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Lung Small Cell Carcinoma 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Lung Small Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Esophageal Neoplasmcancer 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Esophageal Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Liver Neoplasm 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Liver Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Neoplasm 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Non-Muscle Invasive Bladder Carcinoma 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Non-Muscle Invasive Bladder Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Oral Cavity Verrucous Carcinoma 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Oral Cavity Verrucous Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Oropharyngeal Squamous Cell Carcinoma 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Oropharyngeal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Pancreatic Acinar Cell Carcinoma 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Pancreatic Acinar Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Pancreatic Neoplasm 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Pancreatic Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Solid Neoplasm 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Solid Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Tongue Carcinoma 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Tongue Carcinoma	1	Observed	clinicaltrials	graph →

Porfimer investigated in trials for …INVESTIGATED_IN_TRIALSderived25 of 25show fewer

→ investigated in trials for

Lung Non-Small Cell Carcinomasubtype

6 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Lung Non-Small Cell Carcinoma

Observed

Porfimer studied in …STUDIED_INderived10 of 25show all (up to 200)
→ studied in	NCT03735095Phase 1/Phase 2 · completed Endobronchial Ultrasound Guided Interstitial Photodynamic Therapy in Treating Patients With Locally Advanced Lung Cancer · 25 trials list this drug (1 active)	—	—	Solid Neoplasm,Lung Carcinoma,Malignant Lung Neoplasm+2	1	Observed	clinicaltrials	graph →
→ studied in	NCT03678350Phase 1 · completed Light Dosimetry for Photodynamic Therapy With Porfimer Sodium in Treating Participants With Malignant Mesothelioma or Non-Small Cell Lung Cancer With Pleural Disease Undergoing Surgery · 25 trials list this drug (1 active)	—	—	Malignant Mesothelioma,Lung Non-Small Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04836429Phase 1 · terminated Photodynamic Therapy to Amplify the Response to Immunotherapy in Patients With Non-small Cell Lung Cancer With Pleural Disease · 25 trials list this drug (1 active)	—	—	Lung Non-Small Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02153229Phase 2 · active not recruiting Phase II Trial of Radical Pleurectomy With or Without Intraoperative PDT for Malignant Pleural Mesothelioma · 25 trials list this drug (1 active)	—	—	not mapped	1	Observed	clinicaltrials	graph →
→ studied in	NCT03727061Phase 1 · terminated Porfimer Sodium Interstitial Photodynamic Therapy With or Without Standard of Care Chemotherapy in Treating Patients With Locally Advanced or Recurrent Head and Neck Cancer · 25 trials list this drug (1 active)	—	—	Head and Neck Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04753918early Phase 1 · unknown Novel Light Delivery Methods for Lung Cancer Photodynamic Therapy - A Pilot Study · 25 trials list this drug (1 active)	—	—	Lung Non-Small Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT00601848Phase 2 · terminated Photodynamic Therapy in Treating Patients With Resectable Non-Small Cell Lung Cancer That Has Spread to the Pleura · 25 trials list this drug (1 active)	—	—	Malignant Neoplasm,Malignant Lung Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT02916745Phase 1 · completed Feasibility Study of Using Navigational Bronchoscopy to Perform PDT-Photofrin® in Unresectable Peripheral Lung Cancer · 25 trials list this drug (1 active)	—	—	Lung Neoplasm,Lung Non-Small Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03344861Phase 1 · completed Safety of PDT-Photofrin® Prior to Lung Surgery · 25 trials list this drug (1 active)	—	—	Lung Neoplasm,Malignant Lung Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT02106559NA · withdrawn Photodynamic Therapy During Surgery in Treating Patients With Pleural Malignancy · 25 trials list this drug (1 active)	—	—	Malignant Mesothelioma,Lung Non-Small Cell Carcinoma	1	Observed	clinicaltrials	graph →

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