Degarelix

other

Identifier: CI-DRUG-00000713
Entity page: /drug/degarelix ↗
Edges: 130

Neighbours: 19 cancers1 genes10 trials2 approvals
Drawn: 32 of 32 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Degarelix approved for …APPROVED_FOR5 of 3
→ approved for	Malignant Prostate Neoplasmcancer	supports	FDA ORIG	Malignant Prostate Neoplasm	1	Regulatory	openfda	graph →
→ approved for	Malignant Prostate Neoplasmcancer 2 source records aggregated	supports

Degarelix targets …TARGETS1 of 1
→ targets	GNRHR	—	ANTAGONIST	—	1	Curated	chembl	graph →

Degarelix targets …TARGETS1 of 1

→ targets

GNRHR

—

ANTAGONIST

—

Curated

Degarelix investigated for …INVESTIGATED_FOR4 of 4
→ investigated for	Prostate Neoplasmsubtype	unknown	4	Prostate Neoplasm	1	Curated	chembl	graph →
→ investigated for	Neoplasmcancer_family	unknown	3	Neoplasm	1	Curated	chembl	graph →
→ investigated for	Breast Neoplasmcancer_family	unknown	2	Breast Neoplasm	1	Curated	chembl	graph →
→ investigated for	Adenocarcinomahistology	unknown	2	Adenocarcinoma	1	Curated	chembl	graph →

Degarelix investigated in trials for …INVESTIGATED_IN_TRIALSderived16 of 16show fewer
→ investigated in trials for	Malignant Prostate Neoplasmcancer 81 trials (16 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Prostate Neoplasm	81	Observed	clinicaltrials	graph →
→ investigated in trials for	Prostate Adenocarcinoma 13 trials (9 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Prostate Adenocarcinoma	13	Observed	clinicaltrials	graph →
→ investigated in trials for	Prostate Neoplasmsubtype 6 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Prostate Neoplasm	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Prostate Carcinoma 5 trials (4 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Prostate Carcinoma	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Castration-Resistant Prostate Carcinoma 3 trials (2 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Castration-Resistant Prostate Carcinoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Castration-Sensitive Prostate Carcinoma 2 trials (2 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Castration-Sensitive Prostate Carcinoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Bladder Neoplasm 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Bladder Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Hormone Receptor-Negative Breast Carcinoma 1 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Hormone Receptor-Negative Breast Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Invasive Breast Carcinoma of No Special Type 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Invasive Breast Carcinoma of No Special Type	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Leukemia 1 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Leukemia	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Male Breast Carcinoma 1 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Male Breast Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Bladder Neoplasm 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Bladder Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Multiple Myeloma 1 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Multiple Myeloma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Myelodysplastic Syndrome 1 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Myelodysplastic Syndrome	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Non-Hodgkin Lymphoma 1 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Non-Hodgkin Lymphoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Oligometastatic Prostate Carcinoma 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Oligometastatic Prostate Carcinoma	1	Observed	clinicaltrials	graph →

Degarelix studied in …STUDIED_INderived10 of 106show all (up to 200)
→ studied in	NCT03070886Phase 2/Phase 3 · active not recruiting Antiandrogen Therapy and Radiation Therapy With or Without Docetaxel in Treating Patients With Prostate Cancer That Has Been Removed by Surgery · 106 trials list this drug (23 active)	—	—	Prostate Adenocarcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07335796Phase 2 · active not recruiting A Study of BMS986365 in Combination With Degarelix in People With Prostate Cancer · 106 trials list this drug (23 active)	—	—	Malignant Prostate Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT02005887Phase 2 · completed TRial on the Endocrine Activity of Neoadjuvant Degarelix · 106 trials list this drug (23 active)	—	—	not mapped	1	Observed	clinicaltrials	graph →
→ studied in	NCT05501704Phase 2 · recruiting ETHAN - ET for Male BC · 106 trials list this drug (23 active)	—	—	Male Breast Carcinoma,Hormone Receptor-Negative Breast Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04423211Phase 3 · recruiting Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging · 106 trials list this drug (23 active)	—	—	Prostate Adenocarcinoma,Malignant Prostate Neoplasm,Prostate Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04513717Phase 3 · active not recruiting Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a High Gene Risk Score, The PREDICT-RT Trial · 106 trials list this drug (23 active)	—	—	Prostate Adenocarcinoma,Malignant Prostate Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT05050084Phase 3 · active not recruiting Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score, The Guidance Trial · 106 trials list this drug (23 active)	—	—	Prostate Adenocarcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT01786265Phase 2 · active not recruiting Finite Androgen Ablation With or Without Abiraterone Acetate and Prednisone in Treating Patients With Recurrent Prostate Cancer · 106 trials list this drug (23 active)	—	—	Prostate Adenocarcinoma,Prostate Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07455903Phase 2 · recruiting Assessing Efficacy of Neoadjuvant ADT in Localized High-Risk Prostate Cancer Patients Utilizing 18F-Flotufolastat PSMA PET/CT · 106 trials list this drug (23 active)	—	—	Malignant Prostate Neoplasm,Prostate Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT01542021NA · completed Androgen Deprivation Therapy Prior to Prostatectomy for Patients With Intermediate and High Risk Prostate Cancer · 106 trials list this drug (23 active)	—	—	Malignant Prostate Neoplasm	1	Observed	clinicaltrials	graph →

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