| Buparlisib studied in …STUDIED_INderived72 of 72show fewer |
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| → studied in | NCT01339052Phase 2 · completed Phase II Study of BKM120 for Subjects With Recurrent Glioblastoma · 72 trials list this drug (0 active) | — | — | Glioblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04975958Phase 1 · completed Double/Triple Combinations of AN2025, AN0025 and Atezolizumab in Advanced Solid Tumors · 72 trials list this drug (0 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02113878Phase 1 · completed Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and Neck · 72 trials list this drug (0 active) | — | — | Carcinoma,Laryngeal Carcinoma,Malignant Hypopharyngeal Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02159066Phase 2 · completed LGX818 and MEK162 in Combination With a Third Agent (BKM120, LEE011, BGJ398 or INC280) in Advanced BRAF Melanoma · 72 trials list this drug (0 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01397877Phase 2 · completed GINECO-EN102b - BKM120 as Monotherapy in the Treatment of Initial or Recurrent Metastatic Endometrial Cancer · 72 trials list this drug (0 active) | — | — | Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02340780Phase 2 · completed Buparlisib in Patients With Relapsed and Refractory Chronic Lymphocytic Leukemia · 72 trials list this drug (0 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01591421Phase 1/Phase 2 · completed P13Kinase Inhibitor BKM120 in Combination With Panitumumab in Metastatic/Advanced RAS-Wild Type Colorectal Cancer. · 72 trials list this drug (0 active) | — | — | Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01971489Phase 1 · withdrawn Buparlisib, Gemcitabine Hydrochloride, and Cisplatin in Treating Patients With Advanced Solid Tumors · 72 trials list this drug (0 active) | — | — | Adult Solid Neoplasm,Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02756247Phase 1 · completed A Clinical Trial of Buparlisib and Ibrutinib in Lymphoma · 72 trials list this drug (0 active) | — | — | Lymphoma,Diffuse Large B-Cell Lymphoma,Follicular Lymphoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02117817Phase 1 · withdrawn Phase I BKM120/Abraxane in Solid Tumors, Expansion Phase Recurrent Endometrial or Ovarian Cancer · 72 trials list this drug (0 active) | — | — | Malignant Ovarian Neoplasm,Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01540253Phase 1 · completed PI3K Inhibitor BKM120 and Docetaxel in Treating Patients With Advanced Solid Tumor That is Locally Advanced, Cannot Be Removed By Surgery, or Metastatic · 72 trials list this drug (0 active) | — | — | Adult Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02049541Phase 1 · completed Study of BKM120 & Rituximab in Patients With Relapsed or Refractory Indolent B-Cell Lymphoma · 72 trials list this drug (0 active) | — | — | Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue,Grade 3 Follicular Lymphoma,Mantle Cell Lymphoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02220855Phase 2 · completed A Study of BKM120 (Buparlisib) in Relapsed or Refractory Thymomas · 72 trials list this drug (0 active) | — | — | Thymoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02000882Phase 2 · completed STAR Cape+BKM120 MBC With Brain Met · 72 trials list this drug (0 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01806649Phase 2 · terminated BKM120 in Esophageal Squamous Cell Carcinoma After Failure of First Line Chemotherapy · 72 trials list this drug (0 active) | — | — | Malignant Esophageal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01816984Phase 1/Phase 2 · completed PI3K Inhibitor BKM120 and Cetuximab in Treating Patients With Recurrent or Metastatic Head and Neck Cancer · 72 trials list this drug (0 active) | — | — | Malignant Salivary Gland Neoplasm,Laryngeal Squamous Cell Carcinoma,Laryngeal Verrucous Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01551030Phase 2 · completed Buparlisib in Metastatic Transitional Cell Carcinoma of the Urothelium · 72 trials list this drug (0 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01695473Phase 2 · terminated Neoadjuvant BKM120 in High-risk Prostate Cancer · 72 trials list this drug (0 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01468688Phase 1 · completed A Dose-finding Study of a Combination of Imatinib and BKM120 in the Treatment of 3rd Line GIST Patients · 72 trials list this drug (0 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01576666Phase 1 · completed Phase Ib, Dose Escalation Study of Oral LDE225 in Combination With BKM120 in Patients With Advanced Solid Tumors · 72 trials list this drug (0 active) | — | — | Solid Neoplasm,Malignant Breast Neoplasm,Glioblastoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02154776Phase 1 · completed Dose Escalation Study of LEE011 in Combination With Buparlisib and Letrozole in HR+, HER2-negative Post-menopausal Women With Advanced Breast Cancer. · 72 trials list this drug (0 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02088684Phase 1 · completed Study of LEE011 With Fulvestrant and BYL719 or BKM120 in Advanced Breast Cancer · 72 trials list this drug (0 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01155453Phase 1 · completed A Study to Investigate Safety, Pharmacokinetics (PK) and Pharmacodynamics (PD) of BKM120 Plus GSK1120212 in Selected Advanced Solid Tumor Patients · 72 trials list this drug (0 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01626209Phase 1 · completed A Phase I Study of BKM120 in Adult Chinese Patients With Advanced Solid Tumors · 72 trials list this drug (0 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01634061Phase 1 · completed Phase Ib of Abiraterone Acetate Plus BEZ235 or BKM120 in Castration-resistant Prostate Cancer (CRPC) Patients · 72 trials list this drug (0 active) | — | — | Castration-Resistant Prostate Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01934361Phase 1 · completed Phase Ib/II Study of Buparlisib Plus Carboplatin or Lomustine in Patients With Recurrent Glioblastoma Multiforme · 72 trials list this drug (0 active) | — | — | Glioblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01068483Phase 1 · completed Safety of BKM120 Monotherapy in Advanced Solid Tumor Patients · 72 trials list this drug (0 active) | — | — | Malignant Breast Neoplasm,Malignant Ovarian Neoplasm,Malignant Colon Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01283503Phase 1 · completed A Study of BKM120 in Adult Japanese Patients With Advanced Solid Tumors · 72 trials list this drug (0 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01629615Phase 2 · completed A Trial of BKM120 (a PI3K Inhibitor) in Patients With Triple Negative Metastatic Breast Cancer · 72 trials list this drug (0 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01610284Phase 3 · completed Phase III Study of BKM120/Placebo With Fulvestrant in Postmenopausal Patients With Hormone Receptor Positive HER2-negative Locally Advanced or Metastatic Breast Cancer Refractory to Aromatase Inhibitor · 72 trials list this drug (0 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01349660Phase 1/Phase 2 · completed Combination of BKM120 and Bevacizumab in Refractory Solid Tumors and Relapsed/Refractory Glioblastoma Multiforme · 72 trials list this drug (0 active) | — | — | Glioblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02058381Phase 1 · completed A Phase Ib Dose De-escalation Study With BYL719 in Premenopausal Patients With Locally Advanced or Metastatic Breast Cancer · 72 trials list this drug (0 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01816594Phase 2 · completed NeoPHOEBE: Neoadjuvant Trastuzumab + BKM120 in Combination With Weekly Paclitaxel in HER2-positive Primary Breast Cancer · 72 trials list this drug (0 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02614508Phase 1 · terminated Buparlisib and Ofatumumab or Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia · 72 trials list this drug (0 active) | — | — | Chronic Lymphocytic Leukemia,Small Lymphocytic Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02128724Phase 1 · completed Palliative Thoracic Radiotherapy Plus BKM120 · 72 trials list this drug (0 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01737450Phase 2 · completed Activity and Safety Study of BKM120 in Monotherapy in Patient With Metastatic Head and Neck Cancer Recurrent or Progressive · 72 trials list this drug (0 active) | — | — | Head and Neck Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01289041Phase 2 · completed BKM120 as Second-line Therapy for Advanced Endometrial Cancer · 72 trials list this drug (0 active) | — | — | Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01741753Phase 1 · terminated BKM120+Abiraterone Acetate for Metastatic CRPC · 72 trials list this drug (0 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01633060Phase 3 · terminated A Phase III Study of BKM120 With Fulvestrant in Patients With HR+,HER2-, AI Treated, Locally Advanced or Metastatic Breast Cancer Who Progressed on or After mTORi · 72 trials list this drug (0 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02303041Phase 2 · terminated Pilot Study of Sonidegib and Buparlisib in Treating Patients With Advanced or Metastatic Basal Cell Carcinoma · 72 trials list this drug (0 active) | — | — | Skin Neoplasm,Malignant Skin Neoplasm,Basal Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01790932Phase 2 · completed BKM120 For Triple Negative Breast Cancer · 72 trials list this drug (0 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01833169Phase 2 · completed BKM120 for Patients With PI3K-activated Tumors · 72 trials list this drug (0 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01820325Phase 1 · terminated Safety and Efficacy of Buparlisib (BKM120) in Patients With Untreated Squamous Non-small Cell Lung Cancer · 72 trials list this drug (0 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01719250early Phase 1 · completed Buparlisib in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma · 72 trials list this drug (0 active) | — | — | Grade 3 Follicular Lymphoma,Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01693614Phase 2 · completed Safety and Efficacy of BKM120 in Relapsed and Refractory NHL · 72 trials list this drug (0 active) | — | — | Diffuse Large B-Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01923168Phase 2 · completed Study of Letrozole With or Without BYL719 or Buparlisib, for the Neoadjuvant Treatment of Postmenopausal Women · 72 trials list this drug (0 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01911325Phase 1 · terminated Phase II Study of Buparlisib + Docetaxel in Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) Patients · 72 trials list this drug (0 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01852292Phase 2 · terminated Study of Efficacy and Safety of Buparlisib (BKM120) Plus Paclitaxel Versus Placebo Plus Paclitaxel in Recurrent or Metastatic Head and Neck Cancer Previously Pre-treated With a Platinum Therapy · 72 trials list this drug (0 active) | — | — | Head and Neck Squamous Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01870726Phase 1/Phase 2 · terminated Safety and Efficacy of INC280 and Buparlisib (BKM120) in Patients With Recurrent Glioblastoma · 72 trials list this drug (0 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02404844Phase 2 · completed Trial of BKM120/Tamoxifen-combination in Patients With HR-pos, HER2-neg Breast Cancer · 72 trials list this drug (0 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01470209Phase 1 · completed A Phase I Study of BKM120 and Everolimus in Advanced Solid Malignancies · 72 trials list this drug (0 active) | — | — | Solid Neoplasm,Malignant Lung Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02194049Phase 1 · completed Cisplatin, Etoposide and PI3K Inhibitor BKM120 in Treating Patients With Advanced Solid Tumors or Small Cell Lung Cancer · 72 trials list this drug (0 active) | — | — | Adult Solid Neoplasm,Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02301364Phase 2 · completed Buparlisib (BKM120) In Patients With Recurrent/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Recurrent/Refractory Secondary Central Nervous System Lymphoma (SCNSL) · 72 trials list this drug (0 active) | — | — | Lymphoma,Primary Central Nervous System Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01385293Phase 2 · terminated BKM120 in Metastatic Castration-resistant Prostate Cancer · 72 trials list this drug (0 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02452294Phase 2 · unknown Buparlisib in Melanoma Patients Suffering From Brain Metastases (BUMPER) · 72 trials list this drug (0 active) | — | — | Melanoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01571024Phase 1 · completed BKM120 + mFOLFOX6 in Advanced Solid Tumors With Expansion Cohort Pancreatic Cancer · 72 trials list this drug (0 active) | — | — | Solid Neoplasm,Malignant Pancreatic Neoplasm,Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01613677Phase 2 · withdrawn Phase II, Open Label, Non-randomized, Trial of BKM120 for Metastatic or Locally Advanced Cervical Cancer · 72 trials list this drug (0 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01572727Phase 2/Phase 3 · completed A Study of the Experimental Drug BKM120 With Paclitaxel in Patients With HER2 Negative, Locally Advanced or Metastatic Breast Cancer, With or Without PI3K Activation · 72 trials list this drug (0 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01339442Phase 1 · completed BKM120 and Fulvestrant for Treating Postmenopausal Patients With Estrogen Receptor-Positive Stage IV Breast Cancer · 72 trials list this drug (0 active) | — | — | Breast Neoplasm,Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01304602Phase 1 · completed A Trial of Irinotecan and BKM120 in Previously Treated Advanced Colorectal Cancer · 72 trials list this drug (0 active) | — | — | Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01396499Phase 1 · completed Study to Assess Safety, Tolerability and Preliminary Efficacy of BKM120, PI3K Kinase Inhibitor, With Advanced Leukemias · 72 trials list this drug (0 active) | — | — | Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01830504Phase 2 · unknown A Multicenter Phase II Pilot Open Label · 72 trials list this drug (0 active) | — | — | Malignant Thyroid Gland Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01723800Phase 1 · completed PI3K Inhibitor BKM120, Carboplatin, and Pemetrexed Disodium in Treating Patients With Stage IV Non-Small Cell Lung Cancer · 72 trials list this drug (0 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01132664Phase 1/Phase 2 · terminated Phase 1b/2 Study of BKM120 Plus Trastuzumab in Patients With HER2-positive Breast Cancer · 72 trials list this drug (0 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01248494Phase 1 · completed PhIb BKM120 or BEZ235+Endocrine Treatment in Post-Menopausal Patients With Hormone Receptor + Metastatic Breast Cancer · 72 trials list this drug (0 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01297491Phase 2 · completed Safety and Efficacy of BKM120 in Patients With Metastatic Non-small Cell Lung Cancer · 72 trials list this drug (0 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02035124Phase 2 · withdrawn Cabazitaxel and BKM120 in Patients With Metastatic Castrate-Resistant Prostate Cancer (mCRPC) Previously Treated With Docetaxel · 72 trials list this drug (0 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01501604Phase 2 · withdrawn BKM120 in Cancers With PIK3CA Activating Mutations · 72 trials list this drug (0 active) | — | — | Solid Neoplasm,Malignant Breast Neoplasm,Malignant Lung Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01953445Phase 2 · withdrawn Paclitaxel and BKM120 Before Surgery in Treating Patients With Stage II or III Estrogen Receptor-Positive and HER2-Negative Breast Cancer · 72 trials list this drug (0 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01550380Phase 2 · withdrawn BKM120 in Advanced, Metastatic, or Recurrent Endometrial Cancers · 72 trials list this drug (0 active) | — | — | Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01513356early Phase 1 · completed Pharmacodynamic Study of BKM120 in Breast Cancer · 72 trials list this drug (0 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01527877Phase 2 · unknown Study of BKM120 in Advanced Squamous Cell Carcinoma of Head and Neck · 72 trials list this drug (0 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |