| Acalabrutinib studied in …STUDIED_INderived117 of 117show fewer |
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| → studied in | NCT05952024Phase 2 · recruiting Study of Acalabrutinib and Rituximab in Untreated Elderly and/or Frail Patients With DLBCL · 117 trials list this drug (82 active) | — | — | Diffuse Large B-Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02180711Phase 1/Phase 2 · active not recruiting Study of Acalabrutinib Alone or in Combination Therapy in Subjects With B-cell Non-Hodgkin Lymphoma · 117 trials list this drug (82 active) | — | — | Non-Hodgkin Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07277231Phase 3 · recruiting A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06136559Phase 3 · recruiting A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011) · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia,Small Lymphocytic Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06651970Phase 4 · recruiting Acalabrutinib Monotherapy vs Investigator's Choice of Treatment in Patients With CL Leukaemia and Heart Failure · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04662255Phase 3 · active not recruiting Study of BTK Inhibitor LOXO-305 Versus Approved BTK Inhibitor Drugs in Patients With Mantle Cell Lymphoma (MCL) · 117 trials list this drug (82 active) | — | — | Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04002947Phase 2 · recruiting Acalabrutinib With DA-EPOCH-R or R-CHOP for People With Untreated Diffuse Large B-cell Lymphoma · 117 trials list this drug (82 active) | — | — | Non-Hodgkin Lymphoma,Diffuse Large B-Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04462328Phase 1 · active not recruiting Acalabrutinib and Durvalumab in Primary and Secondary Central Nervous System Lymphoma · 117 trials list this drug (82 active) | — | — | Primary Central Nervous System Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02180724Phase 2 · active not recruiting An Open-label, Phase 2 Study of ACP-196 in Subjects With Waldenström Macroglobulinemia · 117 trials list this drug (82 active) | — | — | Waldenstrom Macroglobulinemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04075292Phase 3 · active not recruiting Study of Acalabrutinib Versus Chlorambucil Plus Rituximab in Adult Subjects With Previously Untreated Chronic Lymphocytic Leukemia · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04115631Phase 2 · active not recruiting A Comparison of Three Chemotherapy Regimens for the Treatment of Patients With Newly Diagnosed Mantle Cell Lymphoma · 117 trials list this drug (82 active) | — | — | Liver Lymphoma,Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04169737Phase 2 · recruiting Acalabrutinib and Venetoclax With or Without Early Obinutuzumab for the Treatment of High Risk, Recurrent, or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia,Small Lymphocytic Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05557695recruiting Observational Study of Acalabrutinib in Patients With Chronic Lymphocytic Leukaemia in the United Kingdom · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06564038Phase 1/Phase 2 · recruiting A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies · 117 trials list this drug (82 active) | — | — | B-Cell Malignant Neoplasm,B-Cell Non-Hodgkin Lymphoma,Chronic Lymphocytic Leukemia+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04624906Phase 2 · active not recruiting Bendamustine, Rituximab and Acalabrutinib in Waldenstrom's Macroglobulinemia · 117 trials list this drug (82 active) | — | — | Waldenstrom Macroglobulinemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05057494Phase 3 · active not recruiting A Study of Acalabrutinib Plus Venetoclax Versus Venetoclax Plus Obinutuzumab in Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma · 117 trials list this drug (82 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05951959Phase 2 · active not recruiting A Study of Acalabrutinib Plus Venetoclax and Rituximab in Participants With Treatment Naïve Mantle Cell Lymphoma · 117 trials list this drug (82 active) | — | — | Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04008706Phase 3 · completed Acalabrutinib Safety Study in Untreated and Relapsed or Refractory Chronic Lymphocytic Leukemia Patients · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02477696Phase 3 · active not recruiting Study of Acalabrutinib (ACP-196) Versus Ibrutinib in Previously Treated Participants With High Risk Chronic Lymphocytic Leukemia (CLL) · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02475681Phase 3 · active not recruiting Acalabrutinib, Obinutuzumab and Chlorambucil in Treatment naïve CLL · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04626791Phase 2 · active not recruiting Modified VR-CAP and Acalabrutinib as First Line Therapy for the Treatment of Transplant-Eligible Patients With Mantle Cell Lymphoma · 117 trials list this drug (82 active) | — | — | Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04404088Phase 2 · active not recruiting Acalabrutinib, Lenalidomide, and Rituximab for the Treatment of CD20 Positive Stage III-IV, Grade 1-3a Follicular Lymphoma · 117 trials list this drug (82 active) | — | — | Grade 3a Follicular Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05197192Phase 3 · recruiting A Phase-3-trial of Acalabrutinib, Obinutuzumab & Venetoclax Compared to Obinutuzumab and Venetoclax in Previously Untreated Patients With High Risk CLL · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05495464early Phase 1 · active not recruiting A Pilot "Window-3" Study of Acalabrutinib Plus Rituximab Followed by Brexucabtagene Autoleucel Therapy in Patients With Previously Untreated High-risk Mantle Cell Lymphoma · 117 trials list this drug (82 active) | — | — | Lymphoma,Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03128879Phase 2 · active not recruiting Venetoclax With Ibrutinib or Acalabrutinib in Pts. With High-risk CLL · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03946878Phase 2 · active not recruiting Venetoclax and Acalabrutinib in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma · 117 trials list this drug (82 active) | — | — | Mantle Cell Lymphoma,Blastoid Variant Mantle Cell Lymphoma,Pleomorphic Variant Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03899337Phase 2 · active not recruiting A Trial of CHOP-R Therapy, With or Without Acalabrutinib, in Patients With Newly Diagnosed Richter's Syndrome · 117 trials list this drug (82 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04765111Phase 2 · active not recruiting Acalabrutinib and Rituximab for the Treatment of Previously Untreated Mantle Cell Lymphoma · 117 trials list this drug (82 active) | — | — | Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07024706Phase 2 · recruiting Phase 2 Study of Disease Risk Mutation-Guided Finite Acalabrutinib+Venetoclax for Relapsed CLL Post-1L Finite cBTKi+BCL2i ± Obinutuzumab · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia,Small Lymphocytic Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06319456Phase 3 · recruiting A Study of Lisaftoclax (APG-2575) Combined With Acalabrutinib Versus Immunochemotherapy for Newly Diagnosed CLL/SLL. · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02970318Phase 3 · active not recruiting A Study of Acalabrutinib vs Investigator's Choice of Idelalisib Plus Rituximab or Bendamustine Plus Rituximab in R/R CLL · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02337829Phase 2 · completed Acalabrutinib in Patients With Relapsed/Refractory and Treatment naïve Deletion 17p CLL/SLL · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia,Small Lymphocytic Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04783415Phase 2 · active not recruiting Acalabrutinib, Umbralisib, and Ublituximab for the Treatment of Previously Untreated Mantle Cell Lymphoma · 117 trials list this drug (82 active) | — | — | Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03328273Phase 1 · active not recruiting A Study of AZD6738 and Acalabrutinib in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03198650Phase 1 · completed A Phase 1 Study of Acalabrutinib in Japanese Adult Patients With Advanced B-cell Malignancies · 117 trials list this drug (82 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04257578Phase 1/Phase 2 · active not recruiting Acalabrutinib and Anti-CD19 CAR T-cell Therapy for the Treatment of B-cell Lymphoma · 117 trials list this drug (82 active) | — | — | B-Cell Non-Hodgkin Lymphoma,Diffuse Large B-Cell Lymphoma,Primary Mediastinal Large B-Cell Lymphoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04529772Phase 3 · active not recruiting A Combination of Acalabrutinib With R-CHOP in Subjects With Previously Untreated Non-GCB DLBCL (ACE-LY-312) · 117 trials list this drug (82 active) | — | — | Diffuse Large B-Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03516617Phase 2 · recruiting Acalabrutinib With or Without Obinutuzumab in Treating Patients With Early-Stage Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia,Small Lymphocytic Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05004064Phase 2 · active not recruiting Acalabrutinib and Rituximab in Previously Untreated Mantle Cell Lymphoma · 117 trials list this drug (82 active) | — | — | Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04906902Phase 1/Phase 2 · active not recruiting Acalabrutinib in CNSL · 117 trials list this drug (82 active) | — | — | Central Nervous System Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04505254Phase 2 · active not recruiting Acalabrutinib and Obinutuzumab for the Treatment of Chronic Lymphocytic Leukemia · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia,Small Lymphocytic Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04566887Phase 2 · active not recruiting Acalabrutinib With R-CHOP in Previously Untreated Mantle Cell Lymphoma · 117 trials list this drug (82 active) | — | — | Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04548648Phase 2 · active not recruiting A Pilot Study of Acalabrutinib in Relapsed/Refractory Primary and Secondary CNS Lymphomas · 117 trials list this drug (82 active) | — | — | Central Nervous System Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07635511Phase 3 · not yet recruiting Acalabrutinib Maleate and Bortezomib for Patients With HLA Antibodies · 117 trials list this drug (82 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04722172Phase 2 · active not recruiting A Study on Limiting Treatment Time With Acalabrutinib Combined With Obinutuzumab in People With CLL or SLL · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia,Small Lymphocytic Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02972840Phase 3 · active not recruiting A Study of BR Alone Versus in Combination With Acalabrutinib in Subjects With Previously Untreated MCL · 117 trials list this drug (82 active) | — | — | Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04941716Phase 2 · recruiting Acalabrutinib in Combination With Venetoclax for the Treatment of Refractory or Recurrent Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma, The AVENUE-2 Trial · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia,Small Lymphocytic Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02362035Phase 1/Phase 2 · completed ACP-196 (Acalabrutinib) in Combination With Pembrolizumab, for Treatment of Hematologic Malignancies · 117 trials list this drug (82 active) | — | — | Hairy Cell Leukemia,Hodgkin Lymphoma,Multiple Myeloma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07582159Phase 2 · not yet recruiting Tafasitamab With Acalabrutinib and Venetoclax for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma,Chronic Lymphocytic Leukemia,Small Lymphocytic Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04657094Phase 2 · active not recruiting Acalabrutinib for the Treatment of Relapsed or Refractory Autoimmune Hemolytic Anemia in Patients With Chronic Lymphocytic Leukemia · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma,Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02029443Phase 1/Phase 2 · active not recruiting ACP-196 (Acalabrutinib), a Novel Bruton Tyrosine Kinase (BTK) Inhibitor, for Treatment of Chronic Lymphocytic Leukemia, Richter's Syndrome or Prolymphocytic Leukemia · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia,Prolymphocytic Leukemia,Small Lymphocytic Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04978584Phase 2 · active not recruiting Rituximab, Lenalidomide, Acalabrutinib, Tafasitamab Alone and With Combination Chemotherapy for the Treatment of Newly Diagnosed Non-germinal Center Diffuse Large B-Cell Lymphoma, Smart Stop Study · 117 trials list this drug (82 active) | — | — | Diffuse Large B-Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05517265completed Acalabrutinib in Patients With Chronic Lymphocytic Leukemia With Direct Oral Anticoagulation (CICERO) · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03863184Phase 2 · active not recruiting Acalabrutinib-Lenalidomide-Rituximab in Patients With Untreated MCL · 117 trials list this drug (82 active) | — | — | Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06205498active not recruiting Acalabrutinib Real World Italian obSErvational Study -ARISE · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03623373Phase 2 · completed Acalabrutinib With Bendamustine / Rituximab Followed by Cytarabine / Rituximab for Untreated Mantle Cell Lymphoma · 117 trials list this drug (82 active) | — | — | Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03932331Phase 1/Phase 2 · active not recruiting Study of Acalabrutinib in Chinese Adult Subjects With Relapsed or Refractory Mantle Cell Lymphoma, Chronic Lymphocytic Leukemia or Other B-cell Malignancies · 117 trials list this drug (82 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04189757Phase 2 · active not recruiting Acalabrutinib for the Treatment of Ibrutinib-Intolerant Mantle Cell Lymphoma · 117 trials list this drug (82 active) | — | — | Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04560322Phase 2 · recruiting Venetoclax-Obinutuzumab +/- Acalabrutinib in R/R CLL · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia,Small Lymphocytic Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06428019Phase 3 · recruiting A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL) · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04646395Phase 2 · active not recruiting Study of Acalabrutinib and Tafasitamab in MZL Patients · 117 trials list this drug (82 active) | — | — | Marginal Zone Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02586857Phase 1/Phase 2 · active not recruiting A Phase 1b/2, Multicenter, Open-label Study of ACP-196 in Subjects With Recurrent Glioblastoma Multiforme (GBM) · 117 trials list this drug (82 active) | — | — | Glioblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05388006Phase 2 · recruiting Acalabrutinib, Venetoclax and Durvalumab for the Treatment of Richter Transformation From Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia,Small Lymphocytic Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05256641Phase 1/Phase 2 · recruiting Acalabrutinib Maintenance for the Treatment of Patients With Large B-cell Lymphoma · 117 trials list this drug (82 active) | — | — | Secondary Central Nervous System Lymphoma,Transformed Non-Hodgkin Lymphoma,Diffuse Large B-Cell Lymphoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04624633Phase 2 · active not recruiting Acalabrutinib, Umbralisib, and Ublituximab (AU2) In Relapsed and Untreated CLL · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia,Small Lymphocytic Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05336812Phase 2 · recruiting Acalabrutinib in Combination With Venetoclax or Obinutuzumab for the Treatment of Treatment-naive Chronic Lymphocytic Leukemia · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia,Small Lymphocytic Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03580928Phase 2 · active not recruiting Acalabrutinib, Venetoclax, and Obinutuzumab for Initial Therapy of CLL · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04883437Phase 2 · recruiting Acalabrutinib and Obinutuzumab for the Treatment of Previously Untreated Follicular Lymphoma or Other Indolent Non-Hodgkin Lymphomas · 117 trials list this drug (82 active) | — | — | Indolent Non-Hodgkin Lymphoma,Mantle Cell Lymphoma,Grade 1 Follicular Lymphoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07377578Phase 3 · recruiting A Study of Rocbrutinib Versus Investigator's Choice of BTK Inhibitors in Patients With Relapsed or Refractory Mantle Cell Lymphoma · 117 trials list this drug (82 active) | — | — | Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05583149Phase 2 · active not recruiting Acalabrutinib + Liso-Cel In R/R Aggressive B-Cell Lymphomas · 117 trials list this drug (82 active) | — | — | B-Cell Non-Hodgkin Lymphoma,Diffuse Large B-Cell Lymphoma,EBV-Positive Diffuse Large B-Cell Lymphoma, Not Otherwise Specified+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04855695Phase 1/Phase 2 · recruiting Avo In R/R And Previously Untreated MCL · 117 trials list this drug (82 active) | — | — | Lymphoma,Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07014917Phase 2 · recruiting Intermittent Versus Continuous Venetoclax With Acalabrutinib for CLL/SLL · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia,Small Lymphocytic Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06054776Phase 2 · recruiting Acalabrutinib, Obinutuzumab, and Glofitamab for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma · 117 trials list this drug (82 active) | — | — | Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04604067Phase 2 · active not recruiting Assessing a ctDNA and PET-oriented Therapy in Patients With DLBCL A Multicenter, Open-label, Phase II Trial. · 117 trials list this drug (82 active) | — | — | Diffuse Large B-Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02296918Phase 1 · completed Acalabrutinib in Combination With Anti-CD20 and Venetoclax in Relapsed/Refractory or Untreated CLL/SLL/PLL · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia,Prolymphocytic Leukemia,Small Lymphocytic Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06757647Phase 2 · recruiting Acalabrutinib for the Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07283965not yet recruiting Zanubrutinib and Acalabrutinib Use and Risk of Atrial Fibrillation in Patients With Chronic B-cell Malignancies · 117 trials list this drug (82 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07052695Phase 1/Phase 2 · recruiting Mosunetuzumab for CLL MRD Clearance · 117 trials list this drug (82 active) | — | — | Leukemia,Lymphoma,Chronic Lymphocytic Leukemia+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02328014Phase 1/Phase 2 · completed Acalabrutinib (ACP-196) in Combination With ACP-319, for Treatment of B-Cell Malignancies · 117 trials list this drug (82 active) | — | — | Multiple Myeloma,Non-Hodgkin Lymphoma,B Acute Lymphoblastic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05065554Phase 2 · active not recruiting ACALA-R In Predominantly Demyelinating IgM Mediated Neuropathy · 117 trials list this drug (82 active) | — | — | IgM Monoclonal Gammopathy of Undetermined Significance,Waldenstrom Macroglobulinemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04484012Phase 2 · recruiting Modified Immune Cells (CD19 CAR T Cells) and Acalabrutinib for the Treatment of Relapsed or Refractory Mantle Cell Lymphoma · 117 trials list this drug (82 active) | — | — | Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05943496Phase 1 · recruiting Tafasitamab, Acalabrutinib, and Obinutuzumab for the Treatment of Previously Untreated Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04198922Phase 2 · active not recruiting Acalabrutinib for the Treatment of Chronic Graft Versus Host Disease · 117 trials list this drug (82 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02157324Phase 1 · active not recruiting Acalabrutinib in Combination With ACP-319, for Treatment of Chronic Lymphocytic Leukemia · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04883749Phase 2 · completed Efficacy of Acalabrutinib in Very Old or Frail Patients With Treatment-naïve or Relapsed/Refractory CLL · 117 trials list this drug (82 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06839872Phase 2 · withdrawn A Study to Investigate the Sequencing Strategy of Pirtobrutinib After Disease Progression on First-line Acalabrutinib Treatment for Adult Participants With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia,Small Lymphocytic Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06846489Phase 2 · recruiting Acalabrutinib Plus Rituximab for the Treatment of Elderly or Low- to Intermediate-Risk Younger Untreated Mantle Cell Lymphoma · 117 trials list this drug (82 active) | — | — | Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04189952Phase 2 · terminated Acalabrutinib in Combination With R-ICE For Relapsed or Refractory Lymphoma · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia,Diffuse Large B-Cell Lymphoma,Marginal Zone Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04685915Phase 2 · withdrawn Copanlisib Plus Ibrutinib or Acalabrutinib in R/R CLL · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04402138Phase 2 · completed Treatment With Acalabrutinib Post Blood or Marrow Transplantation in Subjects With Mantle Cell Lymphoma · 117 trials list this drug (82 active) | — | — | Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03571568Phase 1/Phase 2 · recruiting A Study of BI-1206 in Combination With Rituximab With or Without Acalabrutinib in Subjects With Indolent B-Cell NHL · 117 trials list this drug (82 active) | — | — | Indolent B-Cell Non-Hodgkin Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03492125Phase 1/Phase 2 · terminated A Study Of The Selective PKC-β Inhibitor MS- 553 · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia,Small Lymphocytic Lymphoma,Aggressive Non-Hodgkin Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04630756Phase 1/Phase 2 · completed AZD4573 in Novel Combinations With Anti-cancer Agents in Patients With Advanced Blood Cancer · 117 trials list this drug (82 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04178798Phase 3 · completed Study to Investigate the Use of Acalabrutinib in the Treatment of Patients With Chronic Lymphocytic Leukemia · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia- Binet Staging System | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03787264Phase 2 · completed Sequential Regimen of Bendamustin-Debulking Followed by Obinutuzumab, Acalabrutinib and Venetoclax in Patients With Relapsed/Refractory CLL · 117 trials list this drug (82 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03836261Phase 3 · active not recruiting Study of Acalabrutinib (ACP-196) in Combination With Venetoclax (ABT-199), With and Without Obinutuzumab (GA101) Versus Chemoimmunotherapy for Previously Untreated CLL · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02112526Phase 1 · completed Acalabrutinib (ACP-196), a Btk Inhibitor, for Treatment of de Novo Activated B-cell (ABC) Subtype of Diffuse Large B-Cell Lymphoma · 117 trials list this drug (82 active) | — | — | Diffuse Large B-Cell Lymphoma Activated B-Cell Type | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04930536Phase 4 · completed Acalabrutinib Study in Indian Patients With Chronic Lymphocytic Leukaemia & Relapsed and Refractory Mantle Cell Lymphoma · 117 trials list this drug (82 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03788291Phase 2 · completed Acalabrutinib and High Frequency Low Dose Subcutaneous Rituximab in Patients With Previously Untreated Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia,Small Lymphocytic Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06441097Phase 2 · not yet recruiting Efficacy of Pola-RCHP-X vs Pola-RCHP in Untreated DLBCL · 117 trials list this drug (82 active) | — | — | Diffuse Large B-Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05950997NA · recruiting A Single Arm Study of Acalabrutinib Conbimed With Obinutuzumab in Chinese Patients With Previously Untreated CLL · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05205252Phase 1/Phase 2 · withdrawn A Study of Tazemetostat in Combination With Various Treatments in Participants With Blood Cancer. · 117 trials list this drug (82 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04016805Phase 2 · terminated Study to Assess the Efficacy and Safety of Ublituximab and Umbralisib in Participants With Chronic Lymphocytic Leukemia (CLL) Currently Treated With Ibrutinib, Acalabrutinib or Venetoclax · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04094142Phase 2 · completed Acalabrutinib With Rituximab and Lenalidomide in Relapsed/Refractory B-cell Non-Hodgkin Lymphoma · 117 trials list this drug (82 active) | — | — | B-Cell Non-Hodgkin Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03527147Phase 1 · completed Platform Study for the Treatment of Relapsed or Refractory Aggressive Non-Hodgkin's Lymphoma (PRISM Study) · 117 trials list this drug (82 active) | — | — | Non-Hodgkin Lymphoma,Diffuse Large B-Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04502394Phase 1/Phase 2 · recruiting Safety and Efficacy of KRT-232 in Combination With Acalabrutinib in Subjects With R/R DLBCL or R/R CLL · 117 trials list this drug (82 active) | — | — | Non-Hodgkin Lymphoma,Chronic Lymphocytic Leukemia,Diffuse Large B-Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03736616Phase 2 · unknown Acalabrutinib Plus RICE for Relapsed/Refractory DLBCL · 117 trials list this drug (82 active) | — | — | Diffuse Large B-Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04836832Phase 1 · withdrawn Acalabrutinib and Duvelisib for the Treatment of Relapsed/Refractory Indolent Non-Hodgkin Lymphoma · 117 trials list this drug (82 active) | — | — | Follicular Lymphoma,Indolent Non-Hodgkin Lymphoma,Splenic Marginal Zone Lymphoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04660045Phase 2 · withdrawn Early Intervention With Acalabrutinib in Patients With High Risk CLL · 117 trials list this drug (82 active) | — | — | Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma,Chronic Lymphocytic Leukemia | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03205046Phase 1/Phase 2 · terminated A Study of Acalabrutinib and Vistusertib in Subjects With Relapsed/Refractory B-cell Malignancies · 117 trials list this drug (82 active) | — | — | Diffuse Large B-Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02211014Phase 1 · completed An Open-Label, Phase 1b Study of Acalabrutinib With and Without Dexamethasone in Subjects With Multiple Myeloma · 117 trials list this drug (82 active) | — | — | Multiple Myeloma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02362048Phase 2 · completed ACP-196 Alone and in Combination With Pembrolizumab in Subjects With Advanced or Metastatic Pancreatic Cancer · 117 trials list this drug (82 active) | — | — | Malignant Pancreatic Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02537444Phase 2 · completed Acalabrutinib (ACP-196) Alone and in Combination With Pembrolizumab in Ovarian Cancer (KEYNOTE191) · 117 trials list this drug (82 active) | — | — | Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02448303Phase 2 · completed Pembrolizumab Alone and In Combination With Acalabrutinib (ACP-196) in Subjects With Advanced Non-small Cell Lung Cancer · 117 trials list this drug (82 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02454179Phase 2 · completed Study of the Combination of Acalabrutinib (ACP-196) and Pembrolizumab in Advanced Head and Neck Squamous Cell Carcinoma · 117 trials list this drug (82 active) | — | — | Head and Neck Squamous Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02570711Phase 2 · terminated Phase 2, Nab Paclitaxel/Gemcitabine Alone and in Combination With ACP-196 in Subjects With Metastatic Pancreatic Cancer · 117 trials list this drug (82 active) | — | — | Malignant Pancreatic Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02735876Phase 3 · withdrawn A Study of Acalabrutinib in Combination With Rituximab Versus Ibrutinib Versus Acalabrutinib in Subjects With Relapsed or Refractory Mantle Cell Lymphoma · 117 trials list this drug (82 active) | — | — | Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |