| Abemaciclib studied in …STUDIED_INderived195 of 195show fewer |
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| → studied in | NCT06498648Phase 1/Phase 2 · recruiting Testing the Addition of an Anti-cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (Gemcitabine) for Soft Tissue Sarcoma · 195 trials list this drug (105 active) | — | — | Soft Tissue Sarcoma,Dedifferentiated Liposarcoma,Leiomyosarcoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03994796Phase 2 · active not recruiting Genetic Testing in Guiding Treatment for Patients With Brain Metastases · 195 trials list this drug (105 active) | — | — | Malignant Solid Neoplasm,Brain Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04923542Phase 1/Phase 2 · recruiting SRS & Abemaciclib w/wo Imlunestrant in the Management of HR+/HER2- Breast CA Brain Metastases · 195 trials list this drug (105 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05867251Phase 1/Phase 2 · recruiting Study of AVZO-021 in Patients With Advanced Solid Tumors · 195 trials list this drug (105 active) | — | — | Solid Neoplasm,Malignant Fallopian Tube Neoplasm,Ovarian Carcinoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07492641Phase 3 · recruiting BGB-43395 Plus Letrozole Versus CDK4/6i Plus Letrozole for Patients With Advanced or Metastatic HR+/HER2- Breast Cancer Who Have Not Received Prior Treatment for Advanced or Metastatic Disease · 195 trials list this drug (105 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03643510Phase 2 · completed Evaluating Cancer Response to Treatment With Abemaciclib and Fulvestrant in Women With Recurrent Endometrial Cancer · 195 trials list this drug (105 active) | — | — | Endometrial Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03969706Phase 2 · completed Abemaciclib in Patients With Oligodendroglioma · 195 trials list this drug (105 active) | — | — | Adult Oligodendroglioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05708235Phase 2 · active not recruiting A PoC Study to Evaluate Treatments' Efficacy by Monitoring MRD Using ctDNA in HR-positive/HER2-negative EBC Population · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06179303Phase 2 · recruiting Functional Imaging in Prediction of Response to Abemaciclib for Advanced Hormone Receptor-Positive, HER2-Negative Breast Cancer · 195 trials list this drug (105 active) | — | — | HER2-Negative Breast Carcinoma,Hormone Receptor-Positive Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04964934Phase 3 · active not recruiting Phase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6) · 195 trials list this drug (105 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02693535Phase 2 · recruiting TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer · 195 trials list this drug (105 active) | — | — | Solid Neoplasm,Multiple Myeloma,Non-Hodgkin Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07174336Phase 3 · recruiting A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA) · 195 trials list this drug (105 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07832227Phase 2 · not yet recruiting Imlunestrant/Abemaciclib/Selinexor in Ovarian and Endometrial · 195 trials list this drug (105 active) | — | — | Ovarian Low Grade Serous Adenocarcinoma,Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06025747Phase 1 · recruiting A Phase 1 Study of Neoadjuvant Abemaciclib in Combination With Radiation Therapy for Liposarcomas · 195 trials list this drug (105 active) | — | — | Liposarcoma,Dedifferentiated Liposarcoma,Retroperitoneal Sarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04750928Phase 1/Phase 2 · recruiting Cyclin-Dependent Kinase (CDK)4/6 Inhibitor Abemaciclib for Neurofibromatosis Type I (NF1) Related Atypical Neurofibromas · 195 trials list this drug (105 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06366347Phase 2 · recruiting ALPINE: Maintenance Letrozole/Abemaciclib · 195 trials list this drug (105 active) | — | — | Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03531645Phase 2 · active not recruiting Fulvestrant Plus Abemaciclib in Women With Advanced Low Grade Serous Carcinoma · 195 trials list this drug (105 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04921904Phase 1/Phase 2 · completed Abemaciclib Plus Ramucirumab for Esophageal/Gastroesophageal Junction Ca · 195 trials list this drug (105 active) | — | — | Esophageal Adenocarcinoma,Gastroesophageal Junction Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06065748Phase 3 · active not recruiting A Study to Evaluate Efficacy and Safety of Giredestrant Compared With Fulvestrant (Plus a CDK4/6 Inhibitor), in Participants With ER-Positive, HER2-Negative Advanced Breast Cancer Resistant to Adjuvant Endocrine Therapy (pionERA Breast Cancer) · 195 trials list this drug (105 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04633239Phase 1 · recruiting Testing the Addition of Abemaciclib to Olaparib for Women With Recurrent Ovarian Cancer · 195 trials list this drug (105 active) | — | — | Platinum-Resistant Ovarian Carcinoma,Ovarian High Grade Serous Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03424005Phase 1/Phase 2 · recruiting A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04931342Phase 2 · active not recruiting A Study Evaluating the Efficacy and Safety of Biomarker-Driven Therapies in Patients With Persistent or Recurrent Rare Epithelial Ovarian Tumors · 195 trials list this drug (105 active) | — | — | Malignant Ovarian Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05386108Phase 1/Phase 2 · recruiting Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer · 195 trials list this drug (105 active) | — | — | Neoplasm,Neoplasm by Site,Breast Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05774899Phase 1/Phase 2 · recruiting CB-103 With Either Lenvatinib or Abemaciclib in Patients With NOTCH ACC · 195 trials list this drug (105 active) | — | — | Adenoid Cystic Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03939897Phase 1 · active not recruiting Testing the Addition of Copanlisib to Usual Treatment (Fulvestrant and Abemaciclib) in Metastatic Breast Cancer · 195 trials list this drug (105 active) | — | — | Breast Neoplasm,Breast Carcinoma,HER2-Negative Breast Carcinoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05307705Phase 1 · recruiting A Study of LOXO-783 in Patients With Breast Cancer/Other Solid Tumors · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07100106Phase 1/Phase 2 · recruiting A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02981940Phase 2 · active not recruiting A Study of Abemaciclib in Recurrent Glioblastoma · 195 trials list this drug (105 active) | — | — | Glioblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04802759Phase 1/Phase 2 · recruiting A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer · 195 trials list this drug (105 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02523014Phase 2 · recruiting Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas · 195 trials list this drug (105 active) | — | — | Meningioma,Intracranial Meningioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05548127Phase 1/Phase 2 · active not recruiting TACTIVE-U: A Study to Learn About the Study Medicine (Vepdegestrant) When Given With Other Medicines in People With Advanced or Metastatic Breast Cancer (Sub-Study A) · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06380751Phase 3 · recruiting Saruparib (AZD5305) Plus Camizestrant or Plus Endocrine Therapy, Compared With CDK4/6 Inhibitor Plus Endocrine Therapy or Plus Camizestrant in HR-Positive, HER2-Negative (IHC 0, 1+, 2+/ ISH Non-amplified), BRCA1, BRCA2, or PALB2m Advanced Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04941274Phase 1/Phase 2 · recruiting Abemaciclib in Patients With HIV-associated and HIV-negative Kaposi Sarcoma · 195 trials list this drug (105 active) | — | — | Kaposi Sarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05501704Phase 2 · recruiting ETHAN - ET for Male BC · 195 trials list this drug (105 active) | — | — | Male Breast Carcinoma,Hormone Receptor-Negative Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07191717Phase 2 · recruiting Imlunestrant and Abemaciclib for the Treatment of Estrogen Receptor Positive Breast Cancer in Patients With Minimal Residual Disease, MIRI Trial · 195 trials list this drug (105 active) | — | — | Invasive Breast Carcinoma,Estrogen Receptor-Positive Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02977780Phase 2 · recruiting INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT) · 195 trials list this drug (105 active) | — | — | Glioblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03654833Phase 2 · completed Mesothelioma Stratified Therapy (MiST) : A Multi-drug Phase II Trial in Malignant Mesothelioma · 195 trials list this drug (105 active) | — | — | Malignant Mesothelioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04862663Phase 3 · active not recruiting Capivasertib + CDK4/6i + Fulvestrant for Advanced/Metastatic HR+/HER2- Breast Cancer (CAPItello-292) · 195 trials list this drug (105 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05952557Phase 3 · active not recruiting An Adjuvant Endocrine-based Therapy Study of Camizestrant (AZD9833) in ER+/HER2- Early Breast Cancer (CAMBRIA-2) · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03706365Phase 2/Phase 3 · active not recruiting A Study of Abiraterone Acetate Plus Prednisone With or Without Abemaciclib (LY2835219) in Participants With Prostate Cancer · 195 trials list this drug (105 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05999994Phase 2 · recruiting A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer · 195 trials list this drug (105 active) | — | — | Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06188520Phase 1/Phase 2 · recruiting A First-in-human Dose Escalation and Expansion Study to Evaluate the Safety, and Tolerability of AZD8421 Alone or in Combination in Participants With Selected Advanced or Metastatic Solid Tumors · 195 trials list this drug (105 active) | — | — | High-Grade Serous Ovarian Cancer | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05372640Phase 1 · recruiting Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors · 195 trials list this drug (105 active) | — | — | Malignant Solid Neoplasm,Breast Carcinoma,NUT Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06654037Phase 1 · recruiting Testing the Addition of an Anti-Cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (5-Fluorouracil) for Metastatic, Refractory Colorectal Cancer · 195 trials list this drug (105 active) | — | — | Malignant Colorectal Neoplasm,Microsatellite Stable Colorectal Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04040205Phase 2 · recruiting Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration · 195 trials list this drug (105 active) | — | — | Chondrosarcoma,Osteosarcoma,Soft Tissue Sarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05113537Phase 1/Phase 2 · recruiting Abemaciclib Before 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer · 195 trials list this drug (105 active) | — | — | Prostate Adenocarcinoma,Malignant Prostate Neoplasm,Castration-Resistant Prostate Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04158362Phase 3 · active not recruiting Endocrine Therapy With Abemaciclib or Chemotherapy as Initial Metastatic Treatment in ER+/HER2- Breast Cancer · 195 trials list this drug (105 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04975308Phase 3 · active not recruiting A Study of Imlunestrant, Investigator's Choice of Endocrine Therapy, and Imlunestrant Plus Abemaciclib in Participants With ER+, HER2- Advanced Breast Cancer · 195 trials list this drug (105 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07441369Phase 2 · enrolling by invitation Abemaciclib Combined With FOLFOX/FOLFIRI Regimen in Patients With Advanced Colorectal Liver Metastases Cancer · 195 trials list this drug (105 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04469764Phase 2 · recruiting Abemaciclib for the Treatment of Recurrent Ovarian or Endometrial Cancer · 195 trials list this drug (105 active) | — | — | Primary Peritoneal Carcinoma,Ovarian Carcinoma,Endometrial Carcinoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06413706Phase 2 · active not recruiting A Study Comparing Abemaciclib Plus Temozolomide to Temozolomide Monotherapy in Children and Young Adults With High-grade Glioma Following Radiotherapy · 195 trials list this drug (105 active) | — | — | Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07209449Phase 2 · recruiting A Study of Elacestrant Alone or in Combination With Abemaciclib in People With Endometrial Cancer · 195 trials list this drug (105 active) | — | — | Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03220646Phase 2 · active not recruiting Abemaciclib (LY2835219) in Patients With Recurrent Primary Brain Tumors · 195 trials list this drug (105 active) | — | — | Brain Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05768139Phase 1/Phase 2 · recruiting First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors · 195 trials list this drug (105 active) | — | — | Adult Solid Neoplasm,Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06169371Phase 4 · recruiting Abemaciclib Dose Escalation to Maintain Intensity (ADE-MI) · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06001762Phase 2 · active not recruiting TRADE: Dose Escalation Tolerability of Abemaciclib in HR+ HER2- Early Stage Breast Cancer · 195 trials list this drug (105 active) | — | — | Breast Neoplasm,Malignant Breast Neoplasm,Early Stage Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05288166Phase 3 · active not recruiting A Study of Abemaciclib (LY2835219) With Abiraterone in Men With Prostate Cancer That Has Spread to Other Parts of the Body and is Expected to Respond to Hormonal Treatment (Metastatic Hormone-Sensitive Prostate Cancer) · 195 trials list this drug (105 active) | — | — | Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05999968Phase 1 · terminated Abemaciclib Plus Darolutamide in Prostate Cancer That Has Spread After Initial Treatment · 195 trials list this drug (105 active) | — | — | Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06835972Phase 1/Phase 2 · recruiting A Study of Abemaciclib and Cabozantinib in People With Clear Cell Renal Cell Carcinoma (ccRCC) · 195 trials list this drug (105 active) | — | — | Renal Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06813079Phase 2 · recruiting Using Tumor Models to Determine Treatments · 195 trials list this drug (105 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03675893Phase 2 · recruiting RESOLVE: Abemaciclib + Letrozole +/- Metformin or Gedatolisib in Endometrial Cancer · 195 trials list this drug (105 active) | — | — | Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04188548Phase 1 · active not recruiting A Study of LY3484356 in Participants With Advanced or Metastatic Breast Cancer or Endometrial Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm,Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05573126Phase 1/Phase 2 · recruiting Phase 1/2 Study to Evaluate EP0062 as Monotherapy and in Combination in Patients With Advanced or Metastatic AR+/HER-2-/ER+ Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04614194Phase 2 · recruiting Single Cell Immune and Non-immune Correlates of Response to Neoadjuvant Abemaciclib · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04751929Phase 2 · completed Abemaciclib With or Without Atezolizumab for mCRPC · 195 trials list this drug (105 active) | — | — | Malignant Prostate Neoplasm,Castration-Resistant Prostate Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05617885Phase 1 · completed Neo-DAB: Darolutamide and Abemaciclib in Prostate Cancer · 195 trials list this drug (105 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04616183Phase 1/Phase 2 · active not recruiting LY3214996 and Cetuximab Alone or in Combination With Abemaciclib for the Treatment of Unresectable or Metastatic Colorectal Cancer · 195 trials list this drug (105 active) | — | — | Colorectal Carcinoma,Malignant Colorectal Neoplasm,Colon Adenocarcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05563220Phase 1/Phase 2 · active not recruiting Open-Label Umbrella Study To Evaluate Safety And Efficacy Of Elacestrant In Various Combination In Participants With Metastatic Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02846987Phase 2 · active not recruiting Study of Abemaciclib in Dedifferentiated Liposarcoma · 195 trials list this drug (105 active) | — | — | Sarcoma,Dedifferentiated Liposarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06570031Phase 1 · completed ONO-4578-06:Phase I Study of ONO-4578 and Letrozole Plus CDK4 /6 Inhibitors in Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06678269Phase 1 · recruiting A Study of Abemaciclib and Radiation Therapy in People With Metastatic Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm,HER2-Negative Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04523857Phase 2 · recruiting ABemacicliB or Abemaciclib and HydroxYchloroquine to Target Minimal Residual Disease in Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04169074Phase 2 · terminated Immune Modulation by Abemaciclib in Head and Neck Squamous Cell Carcinoma (HNSCC). (AIM Trial) · 195 trials list this drug (105 active) | — | — | Head and Neck Squamous Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06760637Phase 3 · active not recruiting Study of PF-07220060 With Letrozole in Adults With HR-positive HER2-negative Breast Cancer Who Have Not Received Anticancer Treatment for Advanced/Metastatic Disease · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04010357Phase 2 · completed Targeted Therapy With CDK4/6 Inhibitors in Chemo-Refractory, Rb Wild-Type Extensive SCLC · 195 trials list this drug (105 active) | — | — | Extrapulmonary Small Cell Neuroendocrine Carcinoma,Lung Large Cell Neuroendocrine Carcinoma,Lung Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05872204Phase 2 · recruiting Abemaciclib and Letrozole in Patients With Estrogen Receptor-positive Rare Ovarian Cancer · 195 trials list this drug (105 active) | — | — | Adult Granulosa Cell Tumor | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04305834Phase 2 · recruiting Abemaciclib and Endocrine Therapy in Older Patients With Breast Cancer. · 195 trials list this drug (105 active) | — | — | Breast Carcinoma,Hormone Receptor-Positive Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05608252Phase 1/Phase 2 · recruiting VS-6766+Abema+Fulv in Met HR+/HER- BC · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03310879Phase 2 · recruiting Study of the CDK4/6 Inhibitor Abemaciclib in Solid Tumors Harboring Genetic Alterations in Genes Encoding D-Type Cyclins or Amplification of CDK4 or CDK6 · 195 trials list this drug (105 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06630325Phase 2 · terminated A Precision Medicine Approach (SMMART-ACT) for the Treatment of Patients With Advanced Sarcoma, Prostate, Breast, Ovarian or Pancreatic Cancer · 195 trials list this drug (105 active) | — | — | Malignant Solid Neoplasm,Sarcoma,Breast Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03155997Phase 3 · active not recruiting Endocrine Therapy With or Without Abemaciclib (LY2835219) Following Surgery in Participants With Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05095207Phase 1/Phase 2 · recruiting Abemaciclib in Combination With Bicalutamide for Androgen Receptor-positive, HER2-negative Metastatic Breast Cancer · 195 trials list this drug (105 active) | — | — | Breast Neoplasm,Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05440786Phase 2 · active not recruiting CAMPFIRE: A Study of Abemaciclib (LY2835219) in Participants With Ewing's Sarcoma · 195 trials list this drug (105 active) | — | — | Ewing Sarcoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06810544Phase 1/Phase 2 · recruiting Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss · 195 trials list this drug (105 active) | — | — | Solid Neoplasm,Malignant Lung Neoplasm,Brain Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07112053Phase 2 · recruiting A Vaccine (STEMVAC) With Standard Endocrine-Based Therapy or Chemotherapy for the Treatment of Metastatic Hormone Receptor Positive, HER2 Negative Breast Cancer · 195 trials list this drug (105 active) | — | — | HER2-Negative Breast Carcinoma,Hormone Receptor-Positive Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04486352Phase 1/Phase 2 · recruiting A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer · 195 trials list this drug (105 active) | — | — | Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05735080Phase 1/Phase 2 · recruiting Open-Label Study to Evaluate the Safety, Tolerability, PK, and Efficacy of INX-315 in Patients With Advanced Cancer · 195 trials list this drug (105 active) | — | — | Malignant Neoplasm,Solid Neoplasm,Malignant Breast Neoplasm+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06365788Phase 2 · recruiting Bicalutamide and Abemaciclib in Inoperable or Metastatic Androgen Receptor-positive Triple-negative Breast Cancer · 195 trials list this drug (105 active) | — | — | Triple-Negative Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04791384Phase 1/Phase 2 · terminated Phase Ib/II Trial of Abemaciclib and Elacestrant in Patients With Brain Metastasis Due to HR+/Her2- Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07487129Phase 4 · completed Clinical and Pharmacoeconomic Assessment of CDK4/6 Inhibitors for Treatment of Breast Cancer in Egypt · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05940493Phase 2 · recruiting Abemaciclib in Newly Diagnosed Meningioma Patients · 195 trials list this drug (105 active) | — | — | Meningioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04293393Phase 2 · active not recruiting Neoadjuvant Study Chemotherapy vs Letrozole + Abemaciclib in HR+/HER2- High/Intermediate Risk Breast Cancer Patients · 195 trials list this drug (105 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05524584Phase 2 · recruiting Anastrazole, Fulvestrant & Abemaciclib for HR+HER2- Metastatic Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04393285Phase 2 · active not recruiting Abemaciclib and Letrozole to Treat Endometrial Cancer · 195 trials list this drug (105 active) | — | — | Malignant Endometrial Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04391595early Phase 1 · completed LY3214996 Plus Abemaciclib in Recurrent Glioblastoma Patients · 195 trials list this drug (105 active) | — | — | Glioblastoma,Glioma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07428018Phase 2 · not yet recruiting Pragmatic Study to Optimize Neoadjuvant Treatment and Surgical De-escalation in HR+/HER2- Early Breast Cancer Using Oncotype DX and Abemaciclib · 195 trials list this drug (105 active) | — | — | Breast Neoplasm,Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04238819Phase 1/Phase 2 · completed A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma · 195 trials list this drug (105 active) | — | — | Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03130439Phase 2 · terminated Abemaciclib for Patients With Retinoblastoma-Positive, Triple Negative Metastatic Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02152631Phase 3 · active not recruiting A Study of Abemaciclib (LY2835219) in Participants With Previously Treated KRAS Mutated Lung Cancer · 195 trials list this drug (105 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02747004Phase 2 · active not recruiting A Study of Abemaciclib (LY2835219) Plus Tamoxifen or Abemaciclib Alone in Women With Metastatic Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02763566Phase 3 · active not recruiting A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02246621Phase 3 · active not recruiting A Study of Nonsteroidal Aromatase Inhibitors Plus Abemaciclib (LY2835219) in Postmenopausal Women With Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04481113Phase 1 · completed Abemaciclib and Niraparib Before Surgery for the Treatment of Hormone Receptor Positive HER2 Negative Breast Cancer · 195 trials list this drug (105 active) | — | — | Breast Carcinoma,Invasive Breast Carcinoma,HER2-Negative Breast Carcinoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02057133Phase 1 · active not recruiting A Study of LY2835219 (Abemaciclib) in Combination With Therapies for Breast Cancer That Has Spread · 195 trials list this drug (105 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02779751Phase 1 · active not recruiting A Study of Abemaciclib (LY2835219) in Participants With Non-Small Cell Lung Cancer or Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm,Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05933395Phase 2 · recruiting Genetically-informed Therapy for ER+ Breast Cancer Post-CDK4/6 Inhibitor · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05169567Phase 3 · active not recruiting Abemaciclib (LY2835219) Plus Fulvestrant Compared to Placebo Plus Fulvestrant in Previously Treated Breast Cancer · 195 trials list this drug (105 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03891784Phase 2 · active not recruiting Abemaciclib in Treating Patients With Advanced, Refractory, and Unresectable Digestive System Neuroendocrine Tumors · 195 trials list this drug (105 active) | — | — | Digestive System Neuroendocrine Neoplasm,Digestive System Neuroendocrine Tumor,Foregut Neuroendocrine Tumor+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04584853Phase 3 · active not recruiting PreOperative Endocrine Therapy for Individualised Care With Abemaciclib · 195 trials list this drug (105 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07002177Phase 1/Phase 2 · recruiting A Phase Ib/II Study to Evaluate Multiple Combination Therapies of FWD1802 in Patients With ER+/HER2- BC · 195 trials list this drug (105 active) | — | — | Breast Neoplasm,Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT07292207Phase 2 · not yet recruiting Abemaciclib for Molecular Residual Disease Detected by Circulating Tumor DNA in HR+/HER2- Early Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04603183Phase 2 · completed ABemaciclib, ET ± paclItaxel in aGgressive HR+/HER2- MBC trIaL · 195 trials list this drug (105 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06409390Phase 2 · recruiting Sequential Therapies Modeled on Evolutionary Dynamics for Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06495164active not recruiting A Real-life Study to Understand the Use and Effects of Palbociclib in US Patients With Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03284957Phase 1/Phase 2 · terminated Phase 1/2 Study of Amcenestrant (SAR439859) Single Agent and in Combination With Other Anti-cancer Therapies in Postmenopausal Women With Estrogen Receptor Positive Advanced Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03837821early Phase 1 · active not recruiting (CLONEVO): Cell cycLe inhbitiON to Target the EVolution of UrOthelial Cancer · 195 trials list this drug (105 active) | — | — | Malignant Bladder Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06139107Phase 1 · recruiting RADIANT: Pre-op Radiation With Abemaciclib and Letrozole · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03979508Phase 2 · terminated Abemaciclib in Treating Patients With Surgically Resectable, Chemotherapy Resistant, Triple Negative Breast Cancer · 195 trials list this drug (105 active) | — | — | Breast Lobular Carcinoma In Situ,Breast Ductal Carcinoma In Situ,Invasive Breast Carcinoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03280563Phase 1/Phase 2 · completed A Study of Multiple Immunotherapy-Based Treatment Combinations in Hormone Receptor (HR)-Positive Human Epidermal Growth Factor Receptor 2 (HER2)-Negative Breast Cancer · 195 trials list this drug (105 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02107703Phase 3 · active not recruiting A Study of Abemaciclib (LY2835219) Combined With Fulvestrant in Women With Hormone Receptor Positive HER2 Negative Breast Cancer · 195 trials list this drug (105 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04049227early Phase 1 · completed Abemaciclib and Letrozole in Treating Patients With Endometrial Cancer · 195 trials list this drug (105 active) | — | — | Endometrial Endometrioid Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04681768completed Abemaciclib in Combination With Endocrine Therapy as First Line Therapy in Metastatic Breast Cancer Patients · 195 trials list this drug (105 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02784795Phase 1 · terminated A Study of LY3039478 in Participants With Advanced or Metastatic Solid Tumors · 195 trials list this drug (105 active) | — | — | Solid Neoplasm,Malignant Breast Neoplasm,Soft Tissue Sarcoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04074785early Phase 1 · terminated Abemaciclib w/Bevacizumab in Recurrent GBM Pts w/Loss of CDKN2A/B or Gain or Amplification of CDK4/6 · 195 trials list this drug (105 active) | — | — | Glioblastoma,Brain Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04118036Phase 2 · withdrawn Abemaciclib + Pembrolizumab In Glioblastoma · 195 trials list this drug (105 active) | — | — | Glioblastoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04227327Phase 2 · terminated Study Evaluating Abemaciclib + Aromatase Inhibitors in HR+, HER2- Advanced Breast Cancer Patients (HERMIONE-7) · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04627064Phase 1 · completed ABEMA Alone or in COMBO With MK-6482 · 195 trials list this drug (105 active) | — | — | Clear Cell Renal Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04352777Phase 2 · completed Impact of Endocrine Therapy and Abemaciclib on Host and Tumor Immune Cell Repertoire/Function in Advanced ER+/HER2- Breast Cancer · 195 trials list this drug (105 active) | — | — | Breast Neoplasm,Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04752332Phase 3 · terminated A Study of Abemaciclib (LY2835219) Plus Hormone Therapy in Participants With Early Breast Cancer · 195 trials list this drug (105 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03099174Phase 1 · completed This Study in Patients With Different Types of Cancer (Solid Tumours) Aims to Find a Safe Dose of Xentuzumab in Combination With Abemaciclib With or Without Hormonal Therapies. The Study Also Tests How Effective These Medicines Are in Patients With Lung and Breast Cancer · 195 trials list this drug (105 active) | — | — | Neoplasm,Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04552769Phase 2 · completed Abemaciclib in Metastatic or Locally Advanced Anaplastic/Undifferentiated Thyroid Cancer · 195 trials list this drug (105 active) | — | — | Thyroid Gland Neoplasm,Malignant Thyroid Gland Neoplasm,Thyroid Gland Anaplastic Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05759949Phase 1 · completed First-in-Human Study of RLY-5836 in Advanced Breast Cancer and Other Solid Tumors · 195 trials list this drug (105 active) | — | — | Solid Neoplasm,Adult Solid Neoplasm,Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06805812recruiting Predicting clinicAL outcoMes During First-line CDK4/6 Inhibitors Plus Endocrine Therapy in Patients With Advanced Hormone REceptor-poSitive HER2-negative Breast Cancer: the Retrospective-prospective Multicenter Italian PALMARES-2 Study · 195 trials list this drug (105 active) | — | — | Breast Neoplasm,Malignant Breast Neoplasm,Breast Carcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04256941Phase 2 · terminated Aromatase Inhibitor Therapy With or Without Fulvestrant for the Treatment of HR Positive Metastatic Breast Cancer With an ERS1 Activating Mutation, the INTERACT Study · 195 trials list this drug (105 active) | — | — | Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03763604approved for marketing Named Patient Use Program to Provide Abemaciclib (LY2835219) for the Treatment of Metastatic Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02675231Phase 2 · completed A Study of Abemaciclib (LY2835219) in Women With HR+, HER2+ Locally Advanced or Metastatic Breast Cancer · 195 trials list this drug (105 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04003896Phase 2 · terminated A Study to Evaluate Abemaciclib in Advanced Biliary Tract Carcinoma · 195 trials list this drug (105 active) | — | — | Biliary Tract Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02791334Phase 1 · completed A Study of Anti-PD-L1 Checkpoint Antibody (LY3300054) Alone and in Combination in Participants With Advanced Refractory Solid Tumors · 195 trials list this drug (105 active) | — | — | Solid Neoplasm,Malignant Breast Neoplasm,Cutaneous Melanoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01394016Phase 1 · completed A Phase 1 Study of LY2835219 In Participants With Advanced Cancer · 195 trials list this drug (105 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT06561022Phase 2 · unknown Precision Treatment of HR+ HER2- Advanced Breast Cancer Based on SNF Molecular Subtyping · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04534283Phase 2 · terminated A Basket Trial of an ERK1/2 Inhibitor (LY3214996) in Combination With Abemaciclib. · 195 trials list this drug (105 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04545710Phase 2 · active not recruiting Osimertinib and Abemaciclib in EGFR Mutant Non-Small Cell Lung Cancer After Osimertinib Resistance · 195 trials list this drug (105 active) | — | — | Malignant Lung Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05159245Phase 2 · recruiting The Finnish National Study to Facilitate Patient Access to Targeted Anti-cancer Drugs · 195 trials list this drug (105 active) | — | — | Hematopoietic and Lymphoid Cell Neoplasm,Malignant Neoplasm,Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03905889Phase 1 · terminated A Study of Abemaciclib in Combination With Sunitinib in Metastatic Renal Cell Carcinoma · 195 trials list this drug (105 active) | — | — | Renal Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04408924Phase 2 · completed Abemaciclib (LY2835219) in Men With Heavily Treated Metastatic Castration-Resistant Prostate Cancer · 195 trials list this drug (105 active) | — | — | Castration-Resistant Prostate Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04092673Phase 1/Phase 2 · unknown Study of eFT226 in Subjects With Selected Advanced Solid Tumor Malignancies · 195 trials list this drug (105 active) | — | — | Adult Solid Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03703466Phase 2 · completed A Study of Abemaciclib (LY2835219) With and Without Food in Participants With Metastatic Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03339843Phase 2 · completed Multiorgan Metabolic Imaging Response Assessment of Abemaciclib · 195 trials list this drug (105 active) | — | — | Esophageal Squamous Cell Carcinoma,Urothelial Carcinoma,Cholangiocarcinoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03878524Phase 1 · terminated Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial · 195 trials list this drug (105 active) | — | — | Hematopoietic and Lymphatic System Neoplasm,Hematopoietic and Lymphoid Cell Neoplasm,Malignant Solid Neoplasm+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03997448Phase 2 · terminated Abemaciclib and Pembrolizumab in Locally Advanced Unresectable or Metastatic Gastroesophageal Adenocarcinoma: Big Ten Cancer Research Consortium BTCRC-GI18-149 · 195 trials list this drug (105 active) | — | — | Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05891093Phase 3 · recruiting Efficacy and Safety of Fluzoparib Combined With Adjuvant Endocrine Therapy for HR+/HER2- SNF3-subtype Early Breast Cancer (BCTOP-L-A01) · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02925234Phase 2 · recruiting The Drug Rediscovery Protocol (DRUP Trial) · 195 trials list this drug (105 active) | — | — | Neoplasm,Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05464173Phase 1/Phase 2 · unknown Chidamide in Combination With Abemaciclib and Endocrinotherapy（Doctor's Choice） in Breast Cancer Patients Previously Treated With Palbociclib · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04707196Phase 4 · completed A Study of Abemaciclib in Indian Women With Advanced Breast Cancer · 195 trials list this drug (105 active) | — | — | Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02644460Phase 1 · completed Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors · 195 trials list this drug (105 active) | — | — | Solid Neoplasm,Rhabdoid Tumor,Ewing Sarcoma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01739309Phase 2 · completed Study of LY2835219 for Mantle Cell Lymphoma · 195 trials list this drug (105 active) | — | — | Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04305236Phase 2 · terminated Neo-Adjuvant Abemaciclib With Fulvestrant in Patients With ER/PR +HER Negative Breast Cancer · 195 trials list this drug (105 active) | — | — | Breast Neoplasm,Hormone Receptor-Positive Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04801966NA · terminated Safety and Oversight of the Individually Tailored Treatment Approach: A Novel Pilot Study · 195 trials list this drug (105 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05789771completed Abemaciclib for the Treatment of Luminal Metastatic breAst caNcer in the Real-life Clinical pracTice in Russia. · 195 trials list this drug (105 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05766410Phase 2 · recruiting A Randomized Study Comparing the Immune Modulation Effect of Ribociclib, Palbociclib, and Abemaciclib in ER+/HER2- EBC · 195 trials list this drug (105 active) | — | — | Breast Neoplasm,Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03356223Phase 2 · completed Evaluation of ABEMACICLIB Monotherapy in Patients With Locally Advanced/Metastatic Head and Neck Cancer After Failure of Platinum and Cetuximab or Anti-EGFR-based Therapy and Harboring an Homozygous Deletion of CDKN2A, and/or an Amplification of CCND1 and/or of CDK6 · 195 trials list this drug (105 active) | — | — | Malignant Neoplasm,Malignant Head and Neck Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04514159Phase 1 · completed A Study of ZN-c5 and Abemaciclib in Participants With Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04316169Phase 1 · withdrawn Hydroxychloroquine, Abemaciclib and Endocrine Therapy in Hormone Receptor Positive (HR+)/Her 2 Negative Breast Cancer · 195 trials list this drug (105 active) | — | — | Solid Neoplasm,Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03781960Phase 2 · terminated Abemaciclib and Nivolumab for Subjects With Hepatocellular Carcinoma · 195 trials list this drug (105 active) | — | — | Hepatocellular Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02857270Phase 1 · completed A Study of LY3214996 Administered Alone or in Combination With Other Agents in Participants With Advanced/Metastatic Cancer · 195 trials list this drug (105 active) | — | — | Malignant Neoplasm,Melanoma,Lung Non-Small Cell Carcinoma+1 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02688088Phase 1 · completed A Study of Abemaciclib in Participants With Cancer That is Advanced or Has Spread to Another Part(s) of the Body · 195 trials list this drug (105 active) | — | — | not mapped | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04351230Phase 2 · withdrawn T-DM1 With or Without Abemaciclib for the Treatment of HER2-Positive Metastatic Breast Cancer · 195 trials list this drug (105 active) | — | — | Breast Carcinoma,HER2-Positive Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT01655225Phase 1 · completed A Study of LY3023414 in Participants With Advanced Cancer · 195 trials list this drug (105 active) | — | — | Malignant Neoplasm,Malignant Breast Neoplasm,Malignant Mesothelioma+2 | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03292250Phase 2 · completed Korean Cancer Study Group: Translational bIomarker Driven UMbrella Project for Head and Neck (TRIUMPH), Esophageal Squamous Cell Carcinoma- Part 1 (HNSCC)] · 195 trials list this drug (105 active) | — | — | Head and Neck Neoplasm,Head and Neck Squamous Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05153135completed Description of Treatment Patterns and Description and Comparison of Healthcare Resource Utilization and Costs of Women With Metastatic HR+/HER2- Breast Cancer Treated With CDK4/6 Inhibitors · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT05141240completed A Real-world Analysis of Concomitant Medication Use Among Metastatic Breast Cancer Patients Treated With CDK4/6 Inhibitors · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04165031Phase 1/Phase 2 · terminated A Study of LY3499446 in Participants With Advanced Solid Tumors With KRAS G12C Mutation · 195 trials list this drug (105 active) | — | — | Solid Neoplasm,Lung Non-Small Cell Carcinoma,Malignant Colorectal Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04585724Phase 1 · withdrawn Stereotactic Radiosurgery With Abemaciclib, Ribociclib, or Palbociclib in Treating Patients With Hormone Receptor Positive Breast Cancer With Brain Metastases · 195 trials list this drug (105 active) | — | — | Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04071262Phase 1 · completed A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Therapies in Japanese Participants With Advanced Cancer · 195 trials list this drug (105 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04031885Phase 4 · terminated A Study of Abemaciclib (LY2835219) in Combination With Fulvestrant Compared to Chemotherapy in Women With HR Positive, HER2 Negative Metastatic Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02450539Phase 2 · completed A Study of Abemaciclib (LY2835219) in Participants With Stage IV Squamous Non-small Cell Lung Cancer · 195 trials list this drug (105 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04852081unknown Analysis of Therapy Sequence in Women With HR+, HER2 - mBC in Moscow: A Multicenter Retrospective Observational Study. · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02308020Phase 2 · completed A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer, Non-small Cell Lung Cancer, or Melanoma That Has Spread to the Brain · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm,Melanoma,Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03655444Phase 1/Phase 2 · terminated Abemaciclib + Nivolumab in Patients With Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma That Progressed or Recurred Within Six Months After Platinum-based Chemotherapy · 195 trials list this drug (105 active) | — | — | Head and Neck Squamous Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03846583Phase 1 · withdrawn Tucatinib + Abemaciclib + Herceptin for HER2+ MBC · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02919696Phase 1 · completed A Study of Abemaciclib (LY2835219) in Native Chinese Participants With Advanced and/or Metastatic Cancers · 195 trials list this drug (105 active) | — | — | Malignant Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02079636Phase 1 · completed A Study of Abemaciclib (LY2835219) in Combination With Another Anti-cancer Drug in Participants With Lung Cancer (NSCLC) · 195 trials list this drug (105 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02014129Phase 1 · completed A Study of LY2835219 in Japanese Participants With Advanced Cancer · 195 trials list this drug (105 active) | — | — | Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04220892early Phase 1 · withdrawn Pilot Study of Pembrolizumab Combined With Pemetrexed or Abemaciclib for High Grade Glioma · 195 trials list this drug (105 active) | — | — | High-Grade Glioma, NOS | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT04272645Phase 2 · withdrawn Abemaciclib With or Without Atezolizumab in Metastatic Castration Resistant Prostate Cancer · 195 trials list this drug (105 active) | — | — | Malignant Prostate Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02411591Phase 1 · completed A Study of Necitumumab and Abemaciclib in Participants With Non-Small Cell Lung Cancer (NSCLC) · 195 trials list this drug (105 active) | — | — | Lung Non-Small Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02441946Phase 2 · completed A Neoadjuvant Study of Abemaciclib (LY2835219) in Postmenopausal Women With Hormone Receptor Positive, HER2 Negative Breast Cancer · 195 trials list this drug (105 active) | — | — | Breast Neoplasm,Malignant Breast Neoplasm,Early Stage Breast Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02102490Phase 2 · completed A Study of Abemaciclib (LY2835219) In Participants With Previously Treated Breast Cancer That Has Spread · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02981342Phase 2 · completed A Study of Abemaciclib (LY2835219) Alone or in Combination With Other Agents in Participants With Previously Treated Pancreatic Ductal Adenocarcinoma · 195 trials list this drug (105 active) | — | — | Pancreatic Ductal Adenocarcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03988114Phase 4 · withdrawn A Study of Abemaciclib (LY2835219) in Participants With HR+, HER2- Advanced Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02745769Phase 1 · completed A Study in Advanced Cancers Using Ramucirumab (LY3009806) and Other Targeted Agents · 195 trials list this drug (105 active) | — | — | Malignant Neoplasm,Malignant Colorectal Neoplasm,Mantle Cell Lymphoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02117648Phase 1 · completed A Study of LY2835219 in Participants With Cancer · 195 trials list this drug (105 active) | — | — | Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02831530Phase 2 · completed Randomized Short-term Pre-surgical Study to Assess the Effects of Abemaciclib (LY2835219) in Early Breast Cancer Patients · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT03356587Phase 2 · unknown A Biomarker-driven, Open Label, Single Arm, Multicentre Phase II Study of Abemaciclib in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma Who Failed to Platinum-based Therapy · 195 trials list this drug (105 active) | — | — | Head and Neck Neoplasm,Head and Neck Squamous Cell Carcinoma | 1 | Observed | clinicaltrials | graph → |
| → studied in | NCT02792725approved for marketing Expanded Access Program to Provide Abemaciclib (LY2835219) for the Treatment of Metastatic Breast Cancer · 195 trials list this drug (105 active) | — | — | Malignant Breast Neoplasm | 1 | Observed | clinicaltrials | graph → |