Adenoid Cystic Carcinoma

Observed

← altered in cohorts of

KDM6A

138 / 1,049 cases (13 %) · ssm · acc_2019

—

Observed

← altered in cohorts of

ARID1A

120 / 1,049 cases (11 %) · ssm · acc_2019

—

Observed

← altered in cohorts of

KMT2D

111 / 1,049 cases (11 %) · ssm · acc_2019

—

Observed

← altered in cohorts of

BCOR

109 / 1,049 cases (10 %) · ssm · acc_2019

—

Observed

← altered in cohorts of

KMT2C

99 / 1,049 cases (9.4 %) · ssm · acc_2019

—

Observed

← altered in cohorts of

CREBBP

98 / 1,049 cases (9.3 %) · ssm · acc_2019

—

Observed

← altered in cohorts of

ARID1B

82 / 1,049 cases (7.8 %) · ssm · acc_2019

—

Observed

← altered in cohorts of

TERT

82 / 1,049 cases (7.8 %) · ssm · acc_2019

—

Observed

← altered in cohorts of

TP53

76 / 1,049 cases (7.2 %) · ssm · acc_2019

—

Observed

← altered in cohorts of

EP300

74 / 1,049 cases (7.1 %) · ssm · acc_2019

—

Observed

← altered in cohorts of

RUNX1

71 / 1,049 cases (6.8 %) · ssm · acc_2019

—

Observed

← altered in cohorts of

SPEN

67 / 1,049 cases (6.4 %) · ssm · acc_2019

—

Observed

← altered in cohorts of

BRCA2

64 / 1,049 cases (6.1 %) · ssm · acc_2019

—

Observed

← altered in cohorts of

ATM

59 / 1,049 cases (5.6 %) · ssm · acc_2019

—

Observed

← altered in cohorts of

FAT1

57 / 1,049 cases (5.4 %) · ssm · acc_2019

—

Observed

← altered in cohorts of

PIK3CA

54 / 1,049 cases (5.1 %) · ssm · acc_2019

—

Observed

Adenoid Cystic Carcinoma investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 36show all (up to 200)
→ investigated in trials for	Pembrolizumabmonoclonal_antibody 6 trials (4 active) · roll-up of the cancer and its descendants	—	—	Adenoid Cystic Carcinoma	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Cetuximabmonoclonal_antibody 4 trials (0 active) · roll-up of the cancer and its descendants	—	—	Adenoid Cystic Carcinoma	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Lenvatinibsmall_molecule 4 trials (4 active) · roll-up of the cancer and its descendants	—	—	Adenoid Cystic Carcinoma	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Bevacizumabmonoclonal antibody 3 trials (0 active) · roll-up of the cancer and its descendants	—	—	Adenoid Cystic Carcinoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Erlotinib Hydrochloridesmall molecule 3 trials (0 active) · roll-up of the cancer and its descendants	—	—	Adenoid Cystic Carcinoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Nivolumabmonoclonal antibody 3 trials (3 active) · roll-up of the cancer and its descendants	—	—	Adenoid Cystic Carcinoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Carboplatinsmall molecule 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Adenoid Cystic Carcinoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Everolimussmall_molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Adenoid Cystic Carcinoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Abemaciclibsmall molecule 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Adenoid Cystic Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Akt Inhibitor MK2206 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Adenoid Cystic Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Alvespimycinsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Adenoid Cystic Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Avelumabmonoclonal_antibody 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Adenoid Cystic Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Axitinibsmall_molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Adenoid Cystic Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Bortezomibsmall_molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Adenoid Cystic Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Dasatinibsmall_molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Adenoid Cystic Carcinoma	1	Observed	clinicaltrials	graph →

Adenoid Cystic Carcinoma investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 36show all (up to 200)

→ investigated in trials for

Pembrolizumabmonoclonal_antibody

6 trials (4 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Cetuximabmonoclonal_antibody

4 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Lenvatinibsmall_molecule

4 trials (4 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Bevacizumabmonoclonal antibody

3 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Erlotinib Hydrochloridesmall molecule

3 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Nivolumabmonoclonal antibody

3 trials (3 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Carboplatinsmall molecule

2 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Everolimussmall_molecule

2 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Abemaciclibsmall molecule

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Akt Inhibitor MK2206

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Alvespimycinsmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Avelumabmonoclonal_antibody

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Axitinibsmall_molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Bortezomibsmall_molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Dasatinibsmall_molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

Adenoid Cystic Carcinoma studied in …STUDIED_INderived10 of 95show all (up to 200)
→ studied in	NCT07667400Phase 1/Phase 2 · not yet recruiting Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer · condition mapped ONTOLOGY_EXACT · 95 trials mapped (33 active)	—	—	Adenoid Cystic Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07845097Phase 2 · not yet recruiting Phase II Trial Comparing Stereotactic Body Radiotherapy Versus Active Surveillance for Oligometastatic Adenoid Cystic Carcinoma · condition mapped ONTOLOGY_EXACT · 95 trials mapped (33 active)	—	—	Adenoid Cystic Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06781567Phase 2 · recruiting Clinical Trial of HG146 Administered to Participants With Adenoid Cystic Carcinoma · condition mapped ONTOLOGY_EXACT · 95 trials mapped (33 active)	—	—	Adenoid Cystic Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07162480Phase 2 · recruiting Phase II Trial of Puxitatug Samrotecan (AZD8205) in Advanced, Recurrent or Metastatic (R/M) Aggressive Adenoid Cystic Carcinoma Subtype I (ACC-I) · condition mapped ONTOLOGY_EXACT · 95 trials mapped (33 active)	—	—	Adenoid Cystic Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06462183Phase 1 · active not recruiting Study of Safety and Efficacy of RGT-61159 in Adults With Relapsed/Refractory Adenoid Cystic Carcinoma (ACC) or Colorectal Carcinoma (CRC) · condition mapped ONTOLOGY_EXACT · 95 trials mapped (33 active)	—	—	Adenoid Cystic Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04140526Phase 1/Phase 2 · active not recruiting Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC · condition mapped ONTOLOGY_EXACT · 95 trials mapped (33 active)	—	—	Adenoid Cystic Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05774899Phase 1/Phase 2 · recruiting CB-103 With Either Lenvatinib or Abemaciclib in Patients With NOTCH ACC · condition mapped ONTOLOGY_EXACT · 95 trials mapped (33 active)	—	—	Adenoid Cystic Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02978625Phase 2 · active not recruiting Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers · condition mapped ONTOLOGY_EXACT · 95 trials mapped (33 active)	—	—	Skin Adenoid Cystic Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05010629Phase 2 · active not recruiting 9-ING-41 Plus Carboplatin in Salivary Gland Carcinoma · condition mapped ONTOLOGY_EXACT · 95 trials mapped (33 active)	—	—	Adenoid Cystic Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06891560Phase 2 · recruiting A Study of Enfortumab Vedotin in People With Adenoid Cystic Carcinoma · condition mapped ONTOLOGY_EXACT · 95 trials mapped (33 active)	—	—	Adenoid Cystic Carcinoma	1	Observed	clinicaltrials	graph →

Adenoid Cystic Carcinoma studied in …STUDIED_INderived10 of 95show all (up to 200)

→ studied in

NCT07667400Phase 1/Phase 2 · not yet recruiting

Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer · condition mapped ONTOLOGY_EXACT · 95 trials mapped (33 active)

—

Observed

→ studied in

NCT07845097Phase 2 · not yet recruiting

Phase II Trial Comparing Stereotactic Body Radiotherapy Versus Active Surveillance for Oligometastatic Adenoid Cystic Carcinoma · condition mapped ONTOLOGY_EXACT · 95 trials mapped (33 active)

—

Observed

→ studied in

NCT06781567Phase 2 · recruiting

Clinical Trial of HG146 Administered to Participants With Adenoid Cystic Carcinoma · condition mapped ONTOLOGY_EXACT · 95 trials mapped (33 active)

—

Observed

→ studied in

NCT07162480Phase 2 · recruiting

Phase II Trial of Puxitatug Samrotecan (AZD8205) in Advanced, Recurrent or Metastatic (R/M) Aggressive Adenoid Cystic Carcinoma Subtype I (ACC-I) · condition mapped ONTOLOGY_EXACT · 95 trials mapped (33 active)

—

Observed

→ studied in

NCT06462183Phase 1 · active not recruiting

Study of Safety and Efficacy of RGT-61159 in Adults With Relapsed/Refractory Adenoid Cystic Carcinoma (ACC) or Colorectal Carcinoma (CRC) · condition mapped ONTOLOGY_EXACT · 95 trials mapped (33 active)

—

Observed

→ studied in

NCT04140526Phase 1/Phase 2 · active not recruiting

Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC · condition mapped ONTOLOGY_EXACT · 95 trials mapped (33 active)

—

Observed

→ studied in

NCT05774899Phase 1/Phase 2 · recruiting

CB-103 With Either Lenvatinib or Abemaciclib in Patients With NOTCH ACC · condition mapped ONTOLOGY_EXACT · 95 trials mapped (33 active)

—

Observed

Skin Adenoid Cystic Carcinoma

→ studied in

NCT02978625Phase 2 · active not recruiting

Talimogene Laherparepvec and Nivolumab in Treating Patients With Refractory Lymphomas or Advanced or Refractory Non-melanoma Skin Cancers · condition mapped ONTOLOGY_EXACT · 95 trials mapped (33 active)

—

Observed

→ studied in

NCT05010629Phase 2 · active not recruiting

9-ING-41 Plus Carboplatin in Salivary Gland Carcinoma · condition mapped ONTOLOGY_EXACT · 95 trials mapped (33 active)

—

Observed