NUTM2B — gene · CancerIndex

Curated evidence

Clinical evidence (4)

CIViC items involving this gene, grouped by molecular profile and therapy, with native levels and directions. 50 items per page.

civicCuratedShowing 1–4 of 4 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
NUTM1 Fusion + NUTM2B Fusion + DUX4 Fusion + LEUTX Fusion + NUTM1 Fusion + NUTM2B Fusion + DUX4 FusionDUX4 LEUTX NUTM1 NUTM2B1
(diagnostic)	CIC-Rearranged Sarcoma	Diagnostic	B	Supports Positive	4	submitted	EID12515 The cohort included 44 CIC-rearranged sarcomas (CIC-RS), comprising 18 central nervous system (CNS) and 26 extra-CNS tumors. RNA sequencing (n=27) identified CIC::DUX4 (n=15), CIC::NUTM1 (n=4), CIC::L… (full text at CIViC) PMID 39985394 · Koo et al., 2025 · Open in CIViC	civic
NUTM2A Fusion + NUTM2B Fusion + NUTM2E FusionNUTM2A NUTM2B NUTM2E3
(diagnostic)

Cohorts

Frequency = cases affected / cases profiled within one cohort. Cohorts are never pooled.

Data not yet available

No cohort frequency recorded for this gene.

Literature

25 per page, newest first.

pubmedPublishedShowing 1–3 of 3 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.