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CancerIndexthe global index of cancer

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CancerIndex

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WHO Grade 2 Glioma — Research · CancerIndex

Cancers
Neoplasm
Neoplasm by Morphology
Neuroepithelial, Perineurial, and Schwann Cell Neoplasm
Neuroepithelial Neoplasm
Glioma
Low Grade Glioma
WHO Grade 2 Glioma

Subtype

WHO Grade 2 Glioma

CI-CAN-00007115Explore in graph →

Non-malignant84 active trials28 evidence items

NCIt: C132505

Overview
Statistics
Survival
Genomics
Variants & evidence28
Drugs3
Trials255
Research
Rankings
Sources & provenance

Research activity

PubMed record counts

Each count is the number of PubMed records returned by the exact query shown, at the time it was run. Counts are research-activity signals, not quality measures.

Data not yet available

No PubMed query has been run for this entity. Counts require a MeSH-anchored query built from the entity's terminology mappings; the query string is stored with each count so it can be reproduced.

What CancerIndex knows

Trials tab
Methodology: publication counts

Literature

Linked publications (21)

Publications linked to this entity or its descendants, newest first, 25 per page. Link method and validation status are shown; 'candidate' links have not been reviewed.

pubmedProvenance

Source: PubMed (NLM)
Dataset: PubMed E-utilities
Retrieved: Sep 26, 2026
Layer: normalized (units and labels harmonized; values unchanged)

PublishedShowing 1–21 of 21 publications · bibliographic data as recorded by PubMed; abstracts are not reproduced.

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary.
· Acta Neuropathol · 2016 · PMID 27157931 · validated civic_curation pubmed
MGMT promoter methylation is prognostic but not predictive for outcome to adjuvant PCV chemotherapy in anaplastic oligodendroglial tumors: a report from EORTC Brain Tumor Group Study 26951.
· J Clin Oncol · 2009 · PMID 19901104 · validated civic_curation pubmed
Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups.
· Cancer Cell · 2015 · PMID 25965575 · validated civic_curation pubmed
A single-center study of the clinicopathologic correlates of gliomas with a MYB or MYBL1 alteration.
· Acta Neuropathol · 2019 · PMID 31595312 · validated civic_curation pubmed
Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course.
· Acta Neuropathol · 2020 · PMID 31563982 · validated civic_curation pubmed
Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1.
· Proc Natl Acad Sci U S A · 2013 · PMID 23633565 · validated civic_curation pubmed
Childhood supratentorial ependymomas with YAP1-MAMLD1 fusion: an entity with characteristic clinical, radiological, cytogenetic and histopathological features.

Showing 1–21 of 21 publications

· Brain Pathol · 2019 · PMID 30246434 · validated civic_curation pubmed

C11orf95-RELA fusions drive oncogenic NF-κB signalling in ependymoma.

· Nature · 2014 · PMID 24553141 · validated civic_curation pubmed

A multi-institutional retrospective pooled outcome analysis of molecularly annotated pediatric supratentorial ZFTA-fused ependymoma.

· Neurooncol Adv · 2023 · PMID 37287693 · validated civic_curation pubmed

Molecular grouping and outcomes of young children with newly diagnosed ependymoma treated on the multi-institutional SJYC07 trial.

· Neuro Oncol · 2019 · PMID 30976811 · validated civic_curation pubmed

Supratentorial ependymomas of childhood carry C11orf95-RELA fusions leading to pathological activation of the NF-κB signaling pathway.

· Acta Neuropathol · 2014 · PMID 24562983 · validated civic_curation pubmed

Genetic alterations in uncommon low-grade neuroepithelial tumors: BRAF, FGFR1, and MYB mutations occur at high frequency and align with morphology.

· Acta Neuropathol · 2016 · PMID 26810070 · validated civic_curation pubmed

Progressive low-grade oligodendrogliomas: response to temozolomide and correlation between genetic profile and O6-methylguanine DNA methyltransferase protein expression.

· Cancer · 2006 · PMID 16541434 · validated civic_curation pubmed

Phase I trial of lapatinib in children with refractory CNS malignancies: a Pediatric Brain Tumor Consortium study.

· J Clin Oncol · 2010 · PMID 20713864 · validated civic_curation pubmed

Spinal ependymomas in neurofibromatosis Type 2: a retrospective analysis of 55 patients.

· J Neurosurg Spine · 2011 · PMID 21294614 · validated civic_curation pubmed

Supratentorial non-RELA, ZFTA-fused ependymomas: a comprehensive phenotype genotype correlation highlighting the number of zinc fingers in ZFTA-NCOA1/2 fusions.

· Acta Neuropathol Commun · 2021 · PMID 34389065 · validated civic_curation pubmed

MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas.

· Acta Neuropathol · 2010 · PMID 21046410 · validated civic_curation pubmed

Supratentorial ependymoma with YAP1:FAM118B fusion: A case report.

· Neuropathology · 2021 · PMID 33480048 · validated civic_curation pubmed

An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells.

· Science · 2013 · PMID 23558169 · validated civic_curation pubmed

A De Novo Mouse Model of C11orf95-RELA Fusion-Driven Ependymoma Identifies Driver Functions in Addition to NF-κB.

· Cell Rep · 2018 · PMID 29949764 · validated civic_curation pubmed

Posterior fossa ependymoma H3 K27-mutant: an integrated radiological and histomolecular tumor analysis.

· Acta Neuropathol Commun · 2022 · PMID 36104744 · validated civic_curation pubmed