Hematologic Malignancy
Topoisomerase II Inhibitor-Related Acute Myeloid Leukemia
CI-CAN-00006969Explore in graph →
Hematologic
- NCIt
- C27755
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Hematologic Malignancy
CI-CAN-00006969Explore in graph →
Data completeness0 / 7 dimensions
Computed from entity_counters.completeness · refreshed after each connector run
Definition
Acute myeloid leukemias arising as a result of the mutagenic effect of therapeutic agents targeting DNA-topoisomerase II. The vast majority of patients present without a preceding myelodysplastic phase. The acute myeloid leukemias are usually of the monoblastic or myelomonocytic type. Clonal cytogenetic abnormalities are frequently present and usually involve chromosome 11q23 (MLL gene).
Data updated 23 days agoSource updated 26.08e
Taxonomy
Several hierarchies coexist; edges are listed per hierarchy type with their source.
Parents
Children (0)
Leaf node — no children.
Anatomy
Data updated 20 hours agoSource updated unknowncounters aggregate over descendants
Names
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Key figures
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Data updated 20 hours agoSource updated unknownregistry figures: cdc-uscs · latest year available per metric · counters aggregate over descendants