Subtype
Rectal Neoplasm
CI-CAN-00006564Explore in graph →
Non-malignant434 active trials1 approved drugs5 evidence items
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Subtype
CI-CAN-00006564Explore in graph →
Clinical trials
1,773 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07376980 | The SMART Trial: Modified Single-Stapled Anastomosis in Laparoscopic or Robotic Low Anterior Resection for Rectal Cancer(MST) | enrolling by invitation | N/A | 450 | Korea University Anam HospitalOTHER | 1 | Jan 29, 2026 | clinicaltrials |
| NCT02591407 | Trial Comparing Transversus Abdominis Plane Block Versus Epidural Anesthesia for Pain Management in Colorectal Surgery(TAP) | completed | N/A | 200 | Trinity Health MichiganOTHER |
| 1 |
| Jan 28, 2026 |
| clinicaltrials |
| NCT07373015 | Modified Double Snare Assisted EMR (mDS-EMR) VS ESD for Rectal Neuroendocrine Tumors Smaller Than 1cm | not yet recruiting | N/A | 118 | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical SchoolOTHER | 0 | Jan 28, 2026 | clinicaltrials |
| NCT06688786 | A Pospective, Single-arm, Multicenter Clinical Trial Evaluating Preoperative Neoadjuvant mFOLFOX6 Chemotherapy in Combination With PD1 Monoclonal Antibody in MSS/pMMR Locally Advanced Rectal Cancer(FIRM) | active not recruiting | N/A | 30 | Xinhua Hospital, Shanghai Jiao Tong University School of MedicineOTHER | 1 | Jan 27, 2026 | clinicaltrials |
| NCT07369830 | The Impact of Probiotic Intervention on the Gut Microbiota and Bowel Function | recruiting | N/A | 156 | Huashan HospitalOTHER | 1 | Jan 27, 2026 | clinicaltrials |
| NCT07366047 | Autologous Probiotics in Patients With Defunctioning Ileostomy Following LAR for Rectal Cancer | not yet recruiting | N/A | 40 | Peking University Cancer Hospital & InstituteOTHER | 0 | Jan 26, 2026 | clinicaltrials |
| NCT06914245 | Personalized Care Pathways for Bowel Symptoms in Rectal Cancer Patients_contributing Factors (Treatable)(Treatable) | recruiting | N/A | 150 | KU LeuvenOTHER | 1 | Jan 23, 2026 | clinicaltrials |
| NCT05746195 | Optimization of Adaptive Text Messages for Cancer Survivors (OATS II) | completed | N/A | 46 | University of California, San FranciscoOTHER | 1 | Jan 22, 2026 | clinicaltrials |
| NCT07359989 | Leucine Plus Radiochemotherapy for Neoadjuvant Treatment of Locally Advanced Rectal Cancer | recruiting | N/A | 33 | Second Affiliated Hospital, Zhejiang University, School of MedicineOTHER | 1 | Jan 22, 2026 | clinicaltrials |
| NCT06426927 | PeLear CCC: Proyecto Latino Contra Cancer Colorrectal(PeLear CCC) | completed | N/A | 60 | University of North Carolina, Chapel HillOTHER | 1 | Jan 21, 2026 | clinicaltrials |
| NCT07346534 | Reinforced Versus Conventional Anastomosis in Laparoscopic Low Rectal Cancer Resection: A Comparative Study | enrolling by invitation | N/A | 300 | Shanghai 10th People's HospitalOTHER | 1 | Jan 16, 2026 | clinicaltrials |
| NCT07339904 | ProLARS Trial: Prospective Longitudinal Follow-up of Low Anterior Resection Syndrome (LARS) and COREFO Score After Rectum Surgery in Patients Undergoing Upfront Surgery or Different Neo-adjuvant Treatment Regimens(ProLARS) | recruiting | N/A | 100 | University Hospital, AntwerpOTHER | 1 | Jan 14, 2026 | clinicaltrials |
| NCT06715839 | Target-specific immunoPET Imaging of Digestive System Carcinoma | recruiting | N/A | 400 | RenJi HospitalOTHER | 1 | Dec 31, 2025 | clinicaltrials |
| NCT05943444 | Comparison of Postoperative Anal Function Between Parks and Bacon Techniques in Low Rectal Cancer | recruiting | N/A | 256 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Dec 18, 2025 | clinicaltrials |
| NCT07038122 | Reducing the Resection Range After Neoadjuvant Therapy for Locally Advanced Upper Rectal and Rectosigmoid Junction Cancers(RESET) | active not recruiting | N/A | 874 | Sixth Affiliated Hospital, Sun Yat-sen UniversityOTHER | 1 | Dec 18, 2025 | clinicaltrials |
| NCT02965521 | Survivor Choices for Eating and Drinking - Colorectal Cancer(SUCCEED) | completed | N/A | 50 | University of California, San FranciscoOTHER | 1 | Dec 17, 2025 | clinicaltrials |
| NCT06380101 | Evaluating a Nonessential Amino Acid Restriction (NEAAR) Medical Food With Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer (LARC)(NEAAR-LARC) | recruiting | N/A | 30 | University of South FloridaOTHER | 1 | Dec 10, 2025 | clinicaltrials |
| NCT03628248 | Effect of Endovascular Inferior Mesenteric Artery Embolization on Colonic Perfusion Prior to Rectal Surgery for Rectal Tumor or Sigmoid Colon Surgery(AMIREMBOL) | completed | N/A | 10 | Centre Hospitalier Universitaire de NīmesOTHER | 1 | Dec 4, 2025 | clinicaltrials |
| NCT06236633 | Safety & Efficacy of Ischemic Preconditioning by Embolization of the Inferior Mesenteric Artery in Surgery for Tumors of Lower and Middle Rectum(AMIREMBOL_2) | recruiting | N/A | 30 | Centre Hospitalier Universitaire de NīmesOTHER | 1 | Dec 4, 2025 | clinicaltrials |
| NCT07258797 | Short Course or Long Course Radiotherapy as Total Neoadjuvant Therapy in Locally Advanced Rectal Cancer(SHOOL) | not yet recruiting | N/A | 150 | Rajiv Gandhi Cancer Institute & Research Center, IndiaOTHER | 1 | Dec 2, 2025 | clinicaltrials |
| NCT07241143 | Extra-Peritoneal Tunneling Versus Conventional Drain Fixation After Anterior or Low Anterior Resection(ExPeTuD) | not yet recruiting | N/A | 596 | Yeungnam University HospitalOTHER | 1 | Nov 21, 2025 | clinicaltrials |
| NCT07236827 | A Comparison of Endoscopic Synchronous Injection and Submucosal Dissection(ESISD) and Conventional Endoscopic Submucosal Dissection(CESD) for Granular Mixed Nodular Laterally Spreading Tumor in the Rectum (LST-G-M)(ESISD vs CESD) | not yet recruiting | N/A | 60 | Taihe HospitalOTHER | 0 | Nov 19, 2025 | clinicaltrials |
| NCT01347697 | Collagen Implant (Biological Mesh) Versus GM Flap for Reconstruction of Pelvic Floor After ELAPE in Rectal Cancer(NEAPE) | completed | N/A | 91 | Umeå UniversityOTHER | 2 | Oct 3, 2025 | clinicaltrials |
| NCT04827732 | Hypofractionated Pencil-Beam Scanning Intensity-modulated Proton Therapy (IMPT) in Recurrent Rectal Cancer(IMPARC) | terminated | N/A | 15 | Washington University School of MedicineOTHER | 1 | Sep 29, 2025 | clinicaltrials |
| NCT01843218 | Erectile Rating During the Treatment of Rectal Cancers Localized(METEORR) | completed | N/A | 12 | Institut BergoniéOTHER | 1 | Sep 23, 2025 | clinicaltrials |
| NCT03975491 | The Exercise And Colorectal Cancer Treatment Trial(EXACT) | active not recruiting | N/A | 60 | Pennington Biomedical Research CenterOTHER | 1 | Sep 22, 2025 | clinicaltrials |
| NCT06591572 | Single-port Robotic Transanal Total Mesorectal Excision | completed | N/A | 20 | Daping Hospital and the Research Institute of Surgery of the Third Military Medical UniversityOTHER | 1 | Sep 17, 2025 | clinicaltrials |
| NCT01552226 | Compare Preperitoneal Analgesia to Epidural Analgesia for Pain Control After Colon and Rectal Surgery | completed | N/A | 98 | Trinity Health MichiganOTHER | 1 | Sep 15, 2025 | clinicaltrials |
| NCT05938322 | Ketogenic Diet Compliance in Patients Undergoing Radiotherapy for Pelvic Cancers(KOMPARC) | recruiting | N/A | 194 | Fondazione Policlinico Universitario Agostino Gemelli IRCCSOTHER | 1 | Sep 5, 2025 | clinicaltrials |
| NCT04949646 | Intraoperative Neuromonitoring of Pelvic Autonomous Nerve Plexus During Total Mesorectal Excision | recruiting | N/A | 44 | Larissa University HospitalOTHER | 1 | Sep 4, 2025 | clinicaltrials |
| NCT06217016 | Effect of ICCAUT Strategy on Postoperative Urinary Retention After Radical Rectal Cancer Surgery (ICCAUT-2) | withdrawn | N/A | 0 | The First Hospital of Jilin UniversityOTHER | 1 | Aug 28, 2025 | clinicaltrials |
| NCT07137000 | The Effect of Art Therapy in Patients Undergoing Colorectal Cancer | active not recruiting | N/A | 96 | Saglik Bilimleri UniversitesiOTHER | 1 | Aug 22, 2025 | clinicaltrials |
| NCT07134296 | Magnetic Resonance Imaging (MRI)-Guided Rectal Cancer Preservation Program | not yet recruiting | N/A | 32 | Clinica Universidad de Navarra, Universidad de NavarraOTHER | 0 | Aug 21, 2025 | clinicaltrials |
| NCT06087718 | Feasibility of the Maastro Applicator in Rectal Cancer | active not recruiting | N/A | 10 | Maastricht Radiation OncologyOTHER | 1 | Aug 14, 2025 | clinicaltrials |
| NCT07080411 | the Efficacy of MR-guided Online Adaptive Radiotherapy for Locally Advanced Rectal Cancer | not yet recruiting | N/A | 49 | Cancer Institute and Hospital, Chinese Academy of Medical SciencesOTHER | 0 | Jul 23, 2025 | clinicaltrials |
| NCT05010850 | SafeHeal Colovac Colorectal Anastomosis Protection Device Evaluation (SAFE-2) Pivotal Study(SAFE-2) | terminated | N/A | 18 | SafeHeal IncINDUSTRY | 3 | Jul 3, 2025 | clinicaltrials |
| NCT05789433 | Effects of Aerobic Exercise on Skeletal Muscle Remodeling in Colorectal Cancer(RESTORE) | recruiting | N/A | 70 | AdventHealth Translational Research InstituteOTHER | 1 | Jul 3, 2025 | clinicaltrials |
| NCT07041515 | Knowledge-enhanced Digital Intervention to Prevent Low Anterior Resection Syndrome | not yet recruiting | N/A | 320 | National Cancer Center, KoreaOTHER_GOV | 0 | Jun 27, 2025 | clinicaltrials |
| NCT07035600 | Walking and Sitting Difficulties After Rectal Cancer Surgery(WASA) | not yet recruiting | N/A | 300 | Sahlgrenska University HospitalOTHER | 1 | Jun 25, 2025 | clinicaltrials |
| NCT06209099 | Organ Preservation First Strategy and Intentional Watch and Wait for MRI Defined Low-risk Rectal Cancer | recruiting | N/A | 96 | Peking University Cancer Hospital & InstituteOTHER | 1 | Jun 12, 2025 | clinicaltrials |
| NCT03959839 | Endoscopic Submucosal Dissection vs Local Laparoscopic Surgical Resection (TAMIS/TEO) in Early Rectal Neoplasias(DSETAMIS2018) | completed | N/A | 70 | Dr. Alberto Herreros de Tejada EchanojáureguiOTHER | 1 | Jun 3, 2025 | clinicaltrials |
| NCT06761287 | Optimizing Patient Selection for Surgery Using Pathologic Analysis Following Neoadjuvant Therapy in Locally Advanced Rectal Cancer(OPAL) | recruiting | N/A | 20 | Centre Hospitalier Universitaire Saint PierreOTHER | 1 | May 30, 2025 | clinicaltrials |
| NCT05667181 | The Application Value of da Vinci Linear Cutting Stapler SureForm in Robotic Anus Preserving Surgery for Rectal Cancer | completed | N/A | 276 | Nanchang UniversityOTHER | 1 | May 28, 2025 | clinicaltrials |
| NCT06214988 | Selective Defunctioning Stoma in Low Anterior Resection for Rectal Cancer(SELSA) | recruiting | N/A | 212 | Skane University HospitalOTHER | 1 | May 21, 2025 | clinicaltrials |
| NCT05914766 | An Informational and Supportive Care Intervention for Patients With Locally Advanced Rectal Cancer(PATHWAYS) | recruiting | N/A | 80 | Massachusetts General HospitalOTHER | 1 | May 18, 2025 | clinicaltrials |
| NCT06972160 | Intervention Project to Increase Adherence to Colorectal Cancer Screening in Barcelos/Esposende | recruiting | N/A | 1,038 | Local Health Unit Barcelos/Esposende, Public Health UnitOTHER_GOV | 1 | May 14, 2025 | clinicaltrials |
| NCT06956976 | Preservation Vs. Dissection of No. 253 Lymph Nodes of Robotic Resection for Mid/Low Rectal Cancer(REAL2) | not yet recruiting | N/A | 1,596 | Fudan UniversityOTHER | 1 | May 4, 2025 | clinicaltrials |
| NCT06943690 | Safety and Efficacy Study of Single-port Robotic Versus Multi-port Robotic Radical Rectal Cancer Surgery | not yet recruiting | N/A | 212 | Ruijin HospitalOTHER | 1 | Apr 24, 2025 | clinicaltrials |
| NCT04441580 | Assessing the Additional Neoplasia Yield of Computer-aided Colonoscopy in a Screening Setting(GENIAL-CO) | completed | N/A | 900 | Fondazione Poliambulanza Istituto OspedalieroOTHER | 1 | Apr 10, 2025 | clinicaltrials |
| NCT06740357 | Implementation of a Tumor Response Assessment Program Integrating the Shared Medical Decision Into the Organ Preservation Strategy for Rectal Cancer Patients(EVAREC) | recruiting | N/A | 270 | Centre Hospitalier Universitaire DijonOTHER | 1 | Apr 9, 2025 | clinicaltrials |
Data updated 23 days agoSource updated Jan 29, 2026source: clinicaltrials