Clinical trial · Interventional
Compare Preperitoneal Analgesia to Epidural Analgesia for Pain Control After Colon and Rectal Surgery
Prospective Randomized Clinical Trial to Compare Continuous Preperitoneal Analgesia to Continuous Epidural Analgesia for Pain Control After Colon and Rectal Surgery
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a prospective randomized study of 114 patients. The purpose of this study is to compare the efficacy of two standard methods of analgesia for pain control in patients undergoing elective colon and rectal surgery, as measured by the Numeric Pain Scale (NPS) and by the need for supplemental narcotic analgesics. This study is designed to determine if postoperative pain control by local analgesics delivered through preperitoneally placed ON-Q Silver Soaker™ catheters (CPA) is equivalent to continuous epidural analgesia (CEA).
Conditions
Conditions (3)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Colon Cancer | Malignant Colon Neoplasm | CURATED_EXACT | 0.92 |
| Colonic Diverticulosis | — | UNRESOLVED | — |
| Rectal Cancer | Malignant Rectal Neoplasm | CURATED_EXACT | 0.92 |
Interventions
Interventions (2)
| Intervention | Type | Mapped drug | Match |
|---|---|---|---|
| Continuous Epidural Analgesia | Device | — | UNRESOLVED |
| Continuous Preperitoneal Analgesia | Device | — | UNRESOLVED |
Design
Arms and outcomes
Arms (2)
- type
- ACTIVE_COMPARATOR
- label
- Continuous Preperitoneal Analgesia (CPA)
- description
- Continuous Preperitoneal Analgesia for pain management
- interventionNames
- Device: Continuous Preperitoneal Analgesia
- type
- ACTIVE_COMPARATOR
- label
- Continuous Epidural Analgesia (CEA)
- description
- Continuous Epidural Analgesia for pain management
- interventionNames
- Device: Continuous Epidural Analgesia
Primary outcomes (6)
- measure
- Postoperative Numerical Pain Score-Day 0
- timeFrame
- Post-operative day 0
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Age \> = 18 years * Scheduled for elective colon or rectal surgery * Surgical procedure either through open laparotomy or via minimal invasive approach (laparoscopic) * Able to provide informed consent * Able to complete patient questionnaire Exclusion Criteria: * Documented allergic reaction to morphine, hydromorphone, lidocaine, bupivicaine and/or fentanyl * Contra-indication to placement of epidural catheter (spinal stenosis, spinal fusion, etc) * Urgent surgery precluding epidural catheter placement * Systemic Infection contraindicating epidural catheter placement * Unwillingness to participate in follow up assessments * Prisoners
References
Publications (0)
Data not yet available