Subtype
Primary Central Nervous System Neoplasm
CI-CAN-00001432Explore in graph →
Non-malignant957 active trials5 approved drugs175 evidence items
- NCIt
- C102871
Loading cancer entity…
Loading cancer entity…
Subtype
CI-CAN-00001432Explore in graph →
Clinical trials
3,294 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT07631338 | Low-grade Gliomas in Argentina: Incidence, Survival, and Therapeutic Strategies | recruiting | — | 40 | Hospital Italiano de Buenos AiresOTHER | 1 | Jun 8, 2026 | clinicaltrials |
| NCT06883214 | Three miRNA Signatures in Glioma: From Molecular Mechanisms to Potential Clinical Application | recruiting | — | 10 | Regina Elena Cancer InstituteOTHER | 1 | Jun 5, 2026 | clinicaltrials |
| NCT07450872 | Symptom Cluster Heterogeneity and Gut Microbiota Mechanisms in Childhood Cancer Survivors(SC-Het-GM-CCS) | recruiting | — | 600 | The Children's Hospital of Zhejiang University School of MedicineOTHER | 1 | Jun 5, 2026 | clinicaltrials |
| NCT02649582 | Adjuvant Dendritic Cell-immunotherapy Plus Temozolomide in Glioblastoma Patients(ADDIT-GLIO) | active not recruiting | Phase 1 / Phase 2 | 20 | University Hospital, AntwerpOTHER | 1 | Jun 4, 2026 | clinicaltrials |
| NCT04547777 | Phase 1 Trial of D2C7-IT in Combination With 2141-V11 for Recurrent Malignant Glioma | recruiting | Phase 1 | 90 | Darell BignerOTHER | 1 | Jun 4, 2026 | clinicaltrials |
| NCT06607692 | Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).(LUPARPED) | recruiting | Phase 1 / Phase 2 | 25 | Fundación de investigación HMOTHER | 1 | Jun 4, 2026 | clinicaltrials |
| NCT07218575 | Double-Blind Trial of Everolimus for Improving Social Abilities in PTEN Germline Mutations | not yet recruiting | Phase 2 / Phase 3 | 60 | Boston Children's HospitalOTHER | 1 | Jun 4, 2026 | clinicaltrials |
| NCT07223034 | A Study of 177Lu-PSMA-617 in People With Gliomas | recruiting | Phase 1 | 20 | Memorial Sloan Kettering Cancer CenterOTHER | 1 | Jun 4, 2026 | clinicaltrials |
| NCT07274787 | Safety And Effectiveness Of NaviFUS System With Bevacizumab In Recurrent Glioblastoma | not yet recruiting | N/A | 10 | University of CincinnatiOTHER | 1 | Jun 4, 2026 | clinicaltrials |
| NCT07627334 | Personalized Targeted Glioblastoma Therapies by ex Vivo Drug Screening: Advanced Brain Tumor TheRApy Clinical Trial In Patients Scheduled for shOrt Course radiatioN(ATTRACTION) | recruiting | N/A | 30 | Medical University of ViennaOTHER | 1 | Jun 4, 2026 | clinicaltrials |
| NCT07628257 | Cerebral Connectivity and Metabolic Phenotype of Gliomas: Prospective Addition of DTI and Rs-fMRI to a Preoperative FDG PET Strategy, With Neuropsychological Correlates and Post-treatment Follow-up(GlioConnect) | not yet recruiting | N/A | 80 | Centre Paul StraussOTHER | 1 | Jun 4, 2026 | clinicaltrials |
| NCT02875314 | HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors | active not recruiting | Phase 4 | 250 | Parth PatelOTHER | 3 | Jun 3, 2026 | clinicaltrials |
| NCT04780009 | Loupe-Based Intraoperative Fluorescence Imaging | recruiting | — | 30 | Guoqiang YuOTHER | 1 | Jun 3, 2026 | clinicaltrials |
| NCT07465796 | A First-in-Human Study of the CIPHER System During Brain Surgery for Newly Diagnosed Glioma(CIPHER) | recruiting | N/A | 10 | Coherence Neuro Australia Pty LimitedINDUSTRY | 1 | Jun 3, 2026 | clinicaltrials |
| NCT03033992 | Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPG | active not recruiting | N/A | 80 | Children's Oncology GroupNETWORK | 1 | Jun 2, 2026 | clinicaltrials |
| NCT04794686 | ETMR One: An International Registry and Research Platform for Children With Embryonal Tumor With Multilayer Rosettes | recruiting | — | 100 | Hackensack Meridian HealthOTHER | 1 | Jun 2, 2026 | clinicaltrials |
| NCT04903080 | HER2-specific Chimeric Antigen Receptor (CAR) T Cells for Children With Ependymoma | active not recruiting | Phase 1 | 50 | Children's Oncology GroupNETWORK | 2 | Jun 2, 2026 | clinicaltrials |
| NCT04978727 | A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma | active not recruiting | Phase 1 | 35 | Children's Oncology GroupNETWORK | 2 | Jun 2, 2026 | clinicaltrials |
| NCT06533163 | Low-Intensity Oscillatory Magnetic Therapy in Patients With Newly Diagnosed Glioblastoma Multiforme (GBM) - An Exposure-time Escalation Pilot Trial(OMX-EFS-01) | recruiting | N/A | 30 | BioTex, Inc.INDUSTRY | 1 | Jun 2, 2026 | clinicaltrials |
| NCT07350850 | A Multicenter, Prospective Clinical Trial With a Concurrent Control Evaluating Methotrexate Combined With Rituximab,Sintilimab and Pirtobrutinib vs. Investigator-Selected Standard of Care in Treatment-Naive PCNSL(PRIME-PCNSL) | recruiting | Phase 2 | 77 | Tongji HospitalOTHER | 1 | Jun 2, 2026 | clinicaltrials |
| NCT07617168 | The Effect of Education Brain Tumors(Education&BT) | recruiting | N/A | 72 | Istanbul University - CerrahpasaOTHER | 1 | Jun 2, 2026 | clinicaltrials |
| NCT07620548 | Laser Interstitial Thermal Therapy (LiTT) With Cemiplimab or Other Chemotherapy in Recurrent Glioblastomas | not yet recruiting | Phase 2 | 99 | Washington University School of MedicineOTHER | 1 | Jun 2, 2026 | clinicaltrials |
| NCT01269853 | Repeated Super-selective Intraarterial Cerebral Infusion of Bevacizumab (Avastin) for Treatment of Relapsed GBM and AA | recruiting | Phase 1 / Phase 2 | 54 | Northwell HealthOTHER | 1 | Jun 1, 2026 | clinicaltrials |
| NCT02861898 | Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma | recruiting | Phase 1 / Phase 2 | 33 | Northwell HealthOTHER | 1 | Jun 1, 2026 | clinicaltrials |
| NCT03213002 | Oral Capecitabine and Temozolomide (CAPTEM) for Newly Diagnosed GBM(CAPTEM) | recruiting | Phase 1 / Phase 2 | 67 | Northwell HealthOTHER | 1 | Jun 1, 2026 | clinicaltrials |
| NCT05271240 | Repeated Superselective Intraarterial Cerebral Infusion (SIACI) of Bevacizumab With Temozolomide and Radiation Compared to Temozolomide and Radiation Alone in Newly Diagnosed GBM | recruiting | Phase 3 | 432 | Northwell HealthOTHER | 1 | Jun 1, 2026 | clinicaltrials |
| NCT05954858 | Surgical Tissue Flap to Bypass the Blood Brain Barrier in Glioblastoma | recruiting | N/A | 32 | Northwell HealthOTHER | 1 | Jun 1, 2026 | clinicaltrials |
| NCT05979064 | Omental Tissue Autograft in Human Recurrent Glioblastoma Multiforme (rGBM) | recruiting | N/A | 10 | Northwell HealthOTHER | 1 | Jun 1, 2026 | clinicaltrials |
| NCT06397560 | PrOton Pulsed reduCed dOse Rate Radiotherapy for Recurrent CNS maligNancies Trial(POPCORN) | recruiting | N/A | 28 | Baptist Health South FloridaOTHER | 1 | Jun 1, 2026 | clinicaltrials |
| NCT07616726 | Exploration and Characterization Ofintratumoral Electrophysiological Heterogeneity in Gliomas Using Magnetoencephalography(GLIOMEG) | not yet recruiting | N/A | 60 | Hospices Civils de LyonOTHER | 1 | Jun 1, 2026 | clinicaltrials |
| NCT07616986 | LITT for Ultra-early GBM Recurrence | recruiting | N/A | 12 | Insel Gruppe AG, University Hospital BernOTHER | 1 | Jun 1, 2026 | clinicaltrials |
| NCT05116137 | The Impact of Resistance ExerciSe on Muscle Mass in GlioblaSToma Survivors(RESIST) | enrolling by invitation | N/A | 24 | Nova Scotia Health AuthorityOTHER | 1 | May 29, 2026 | clinicaltrials |
| NCT05843253 | Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant | recruiting | Phase 2 | 120 | Nationwide Children's HospitalOTHER | 6 | May 29, 2026 | clinicaltrials |
| NCT06831526 | Neoadjuvant Chemoradiotherapy With or Without Concurrent Azeliragon in Patients With Newly Diagnosed Glioblastoma | recruiting | Early Phase 1 | 12 | Washington University School of MedicineOTHER | 1 | May 29, 2026 | clinicaltrials |
| NCT07609472 | FG001 Near-Infrared Fluorescence Imaging During Tumor Resection in Newly Diagnosed High-Grade Glioma | not yet recruiting | Phase 2 | 76 | FluoGuide A/SINDUSTRY | 1 | May 29, 2026 | clinicaltrials |
| NCT06264388 | DB107-Retroviral Replicating Vector (RRV) Combined With DB107-Flucytosine (FC) in Patients With Recurrent Glioblastoma or Anaplastic Astrocytoma | recruiting | Phase 2 | 33 | Ashish ShahOTHER | 1 | May 28, 2026 | clinicaltrials |
| NCT04752280 | Glioblastoma Radiotherapy Using IMRT or Proton Beams(GRIPS) | recruiting | N/A | 326 | University Hospital HeidelbergOTHER | 1 | May 27, 2026 | clinicaltrials |
| NCT06254326 | ADAGiO: Adoptive Cellular Therapy for the TreAtment of Recurrent OliGodendrogliOma (OG) Adult Patients(ADAGiO) | recruiting | Phase 1 | 12 | University of FloridaOTHER | 1 | May 27, 2026 | clinicaltrials |
| NCT07424092 | Intratumoral DNX-2401 for High Grade Pediatric Brain Tumors(PED-DNX2401) | recruiting | Phase 2 | 39 | Clinica Universidad de Navarra, Universidad de NavarraOTHER | 2 | May 27, 2026 | clinicaltrials |
| NCT07608003 | Multicenter Prospective Study on MRI AI Model for Midline Glioma Subtyping and Prognosis: | recruiting | — | 500 | Xiangya Hospital of Central South UniversityOTHER | 1 | May 27, 2026 | clinicaltrials |
| NCT07605364 | Testing the Addition of an Anti-Cancer Drug, Mycophenolate Mofetil, to the Usual Treatment (Radiation Therapy and Temozolomide) for Advanced Brain Cancer | not yet recruiting | Phase 2 / Phase 3 | 422 | Alliance for Clinical Trials in OncologyOTHER | 0 | May 26, 2026 | clinicaltrials |
| NCT03688178 | DC Migration Study to Evaluate TReg Depletion In GBM Patients With and Without Varlilumab(DERIVe) | active not recruiting | Phase 2 | 43 | Annick Desjardins, MDOTHER | 1 | May 22, 2026 | clinicaltrials |
| NCT04635657 | Cognitive Status After Removal of Skull Base Meningioma | recruiting | — | 50 | Ohio State UniversityOTHER | 1 | May 22, 2026 | clinicaltrials |
| NCT05736406 | A Dose-escalation Clinical Study of Intraoperative Photodynamic Therapy of Glioblastoma | active not recruiting | Phase 1 / Phase 2 | 12 | Hemerion TherapeuticsINDUSTRY | 2 | May 22, 2026 | clinicaltrials |
| NCT07411690 | Analysis of Cerebrospinal Fluid Leakage After Surgery for Intracranial Tumors(CSF-IMR) | recruiting | — | 200 | Medical University of WarsawOTHER | 1 | May 22, 2026 | clinicaltrials |
| NCT07479446 | Oliceridine Versus Sufentanil for Postoperative Nausea in Cerebellopontine Angle Surgery | recruiting | N/A | 174 | Xuanwu Hospital, BeijingOTHER | 1 | May 22, 2026 | clinicaltrials |
| NCT07604285 | A Phase 1/2 Study of Safety and Tolerability of MT-125 With Chemoradiation in Patients With Newly Diagnosed MGMT Methylated Glioblastoma(NOVA-GBM) | not yet recruiting | Phase 1 / Phase 2 | 36 | Myosin Therapeutics Inc.INDUSTRY | 1 | May 22, 2026 | clinicaltrials |
| NCT03750513 | LET Optimized IMPT in Treating Pediatric Patients With Ependymoma | recruiting | Phase 1 | 48 | M.D. Anderson Cancer CenterOTHER | 1 | May 20, 2026 | clinicaltrials |
| NCT04087902 | Long-Term Longitudinal QoL in Patients Undergoing EEA | active not recruiting | — | 400 | Ohio State UniversityOTHER | 1 | May 20, 2026 | clinicaltrials |
| NCT07413796 | Comparison of Skin Closure Techniques in Oncological Neurosurgical Procedures: Intradermal Running Suture Versus Transdermal Interrupted Sutures(NEURO-SUTURE) | recruiting | N/A | 382 | Medical University of WarsawOTHER | 1 | May 20, 2026 | clinicaltrials |
Data updated 23 days agoSource updated Jun 8, 2026source: clinicaltrials