Clinical trial · Observational
Long-Term Longitudinal QoL in Patients Undergoing EEA
A Prospective Longitudinal Quality of Life Study in Patients Undergoing Endoscopic Endonasal Skull Base Surgery
NCT04087902CI-TRIAL-00112181active not recruitingClinicalTrials.gov clinicaltrialsProvenance
- Source
- ClinicalTrials.gov
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CLINICALTRIALS-20260908-000001
Summary
Brief summary (as posted)
This is a prospective longitudinal study to access postoperative 2-year quality of life in patients who undergo endonasal endoscopic approach surgeries of the skull base.
Conditions
Conditions (8)
Free-text conditions as registered, with the CancerIndex entity they were reconciled to and the match type.
| Condition (as posted) | Mapped entity | Match | Confidence |
|---|---|---|---|
| Chondrosarcoma | Chondrosarcoma | ONTOLOGY_EXACT | 0.98 |
| Chordoma | Chordoma | ONTOLOGY_EXACT | 0.98 |
| Craniopharyngioma | Craniopharyngioma | ONTOLOGY_EXACT | 0.90 |
| Encephalocele | — | UNRESOLVED | — |
| Esthesioneuroblastoma | Olfactory Neuroblastoma | ALIAS | 0.90 |
| Meningioma | Meningioma | ONTOLOGY_EXACT | 0.90 |
| Pituitary Tumor | Pituitary Gland Neoplasm | ALIAS | 0.90 |
| Rathke Cleft Cysts | — | UNRESOLVED | — |
Interventions
Interventions (0)
Data not yet available
No intervention recorded.
Design
Arms and outcomes
Arms (0)
[]Primary outcomes (1)
- measure
- PROMIS-29 quality of life outcome measures for patients undergoing endoscopic endonasal surgeries.
- timeFrame
- 24-months post-operatively
- description
- This study aims to better understand the long-term overall quality of life of patients undergoing endoscopic endonasal surgery using modern sinonasal reconstruction techniques. The PROMIS-29 metric, an overall quality of life metric, will be used to better understand quality of life for patients undergoing this procedure.
Secondary outcomes (3)
- measure
- ASK Nasal-12 questionnaire used to measure normal time of healing for patients undergoing endoscopic endonasal surgery
- timeFrame
- 24 months post-operatively
- description
- This study aims to better understand the overall nose function in patients undergoing endoscopic endonasal surgery using modern sinonasal techniques. The ASK Nasal-12 metric is designed to evaluate nose overall nose function such as post-nasal drip, ability to smell, and pain.
- measure
- Number of patients with long-term quality of life risk factors using PROMIS-29
Eligibility
Eligibility (as posted)
- Sex
- All
- Minimum age
- 18 Years
Show eligibility criteria text
Inclusion Criteria: * Patient is scheduled to undergo endoscopic endonasal surgery. Multiple, staged surgeries are not exclusionary * 18 years of age or older * The subject must in the investigator's opinion, be psychosocially, mentally, and physically able to fully comply with this protocol including the required follow-up visits, the filling out of required forms, and have the ability to understand and give written informed consent Exclusion Criteria: * Patient is a prisoner * Patient is not English speaking * Patient is not expected to survive until the 2-year follow-up
References
Publications (0)
Data not yet available
No reference posted for this study.