Hematologic Malignancy
Peripheral T-Cell Lymphoma, Not Otherwise Specified
CI-CAN-00008233Explore in graph →
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Hematologic Malignancy
CI-CAN-00008233Explore in graph →
Variants & evidence
2 evidence items mapped to this entity or its descendants, grouped by molecular profile, then therapy. 50 items per page.
| Therapy | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|
| IDH2 R1722 | |||||||
| (diagnostic) | Diagnostic | B | Supports Positive | 4 | accepted | EID628IDH2 R172 mutations were frequently observed in patients with the angioimmunoblastic T-cell lymphoma subtype of peripheral T-cell lymphomas but not observed in other subtypes. PMID 22215888 · Cairns et al., 2012 · Open in CIViC | civic |
| (prognostic) | Prognostic | B | Does Not Support Better Outcome | 3 | accepted | EID627In patients with angioimmunoblastic T-cell lymphoma (a subtype of peripheral T-cell lymphoma), IDH2 R172 mutations (N=16) had no impact on overall survival when compared to patients with wildtype IDH2… (full text at CIViC) PMID 26268241 · Wang et al., 2015 · Open in CIViC | civic |
Data updated 23 hours agoSource updated unknownsource: civic (CC0)
Evidence levels, directions and ratings are those assigned by CIViC curators. "Submitted" items have not completed curation review. This is not treatment guidance.