Cancer Family
Peripheral Nervous System Neoplasm
CI-CAN-00000316Explore in graph →
Non-malignant71 active trials8 evidence items
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Cancer Family
CI-CAN-00000316Explore in graph →
Clinical trials
261 studies whose conditions map to this entity or one of its descendants. Status and phase are as posted on ClinicalTrials.gov. 50 studies per page.
| NCT | Title | Status | Phase | Enrollment (n) | Sponsor | Countries | Last update | Source |
|---|---|---|---|---|---|---|---|---|
| NCT00314119 | Natural History and Biology of Skin Neurofibromas in Neurofibromatosis Type 1 | completed | — | 17 | National Cancer Institute (NCI)NIH | 1 | Sep 28, 2026 | clinicaltrials |
| NCT02211768 | Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1 | completed | Phase 1 | 10 | National Cancer Institute (NCI)NIH | 1 | Aug 4, 2026 | clinicaltrials |
| NCT04573816 | Development of a Tele-monitoring Program for Patients Undergoing Surgery for Pheochromocytoma and / or Paraganglioma(e-PPGL) | completed | — | 132 | Assistance Publique - Hôpitaux de ParisOTHER | 1 | Jul 8, 2026 | clinicaltrials |
| NCT02180867 | Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery | completed | Phase 2 / Phase 3 | 140 | National Cancer Institute (NCI)NIH | 3 | Jun 17, 2026 | clinicaltrials |
| NCT03433183 | SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors | completed | Phase 2 | 21 | Sarcoma Alliance for Research through CollaborationOTHER | 1 | May 27, 2026 | clinicaltrials |
| NCT05005845 | NFX-179 Topical Gel Treatment for Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF) | completed | Phase 2 | 199 | NFlection Therapeutics, Inc.INDUSTRY | 1 | Feb 17, 2026 | clinicaltrials |
| NCT01022515 | Specificity of Elevated Plasma EM66 Levels in Pheochromocytoma(PHEO) | completed | N/A | 60 | University Hospital, RouenOTHER | 1 | Feb 6, 2026 | clinicaltrials |
| NCT07339241 | Abdominal Circumference as a Predictor of Operative Time in Retroperitoneal Adrenalectomy for Pheochromocytoma | completed | — | 159 | Asan Medical CenterOTHER | 0 | Jan 14, 2026 | clinicaltrials |
| NCT06322342 | Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent | completed | Phase 2 | 18 | Reveal Pharmaceuticals Inc.INDUSTRY | 1 | Dec 26, 2025 | clinicaltrials |
| NCT01850888 | MIBG for Refractory Neuroblastoma and Pheochromocytoma | completed | N/A | 15 | Masonic Cancer Center, University of MinnesotaOTHER | 1 | Dec 18, 2025 | clinicaltrials |
| NCT02302833 | Cabozantinib S-malate in Treating Patients With Metastatic Pheochromocytomas or Paragangliomas That Cannot Be Removed by Surgery | completed | Phase 2 | 21 | M.D. Anderson Cancer CenterOTHER | 1 | Jul 31, 2025 | clinicaltrials |
| NCT04400474 | Trial of Cabozantinib Plus Atezolizumab in Advanced and Progressive Neoplasms of the Endocrine System. The CABATEN Study(CABATEN) | completed | Phase 2 | 93 | Grupo Espanol de Tumores NeuroendocrinosOTHER | 1 | Jun 19, 2025 | clinicaltrials |
| NCT04811196 | A Study of Different Dosing Schedules of Selinexor in Sarcoma Patients | completed | Phase 1 | 56 | University Health Network, TorontoOTHER | 1 | May 29, 2025 | clinicaltrials |
| NCT03231306 | Phase II Study of Binimetinib in Children and Adults With NF1 Plexiform Neurofibromas(NF108-BINI) | completed | Phase 2 | 45 | University of Alabama at BirminghamOTHER | 1 | May 2, 2025 | clinicaltrials |
| NCT04730583 | Tolerability of Device Based Therapies for Neurofibromatosis Type 1 Cutaneous Neurofibromas | completed | Phase 1 | 34 | Massachusetts General HospitalOTHER | 1 | Feb 21, 2025 | clinicaltrials |
| NCT06062082 | Intraoperative Hemodynamic Instability During Unilateral Adrenalectomy for Pheochromocytoma(HEMODADRE) | completed | — | 60 | Central Hospital, Nancy, FranceOTHER | 1 | Feb 13, 2025 | clinicaltrials |
| NCT04028479 | The Registry of Oncology Outcomes Associated With Testing and Treatment(ROOT) | completed | — | 167 | Taproot HealthINDUSTRY | 1 | Dec 18, 2024 | clinicaltrials |
| NCT06669481 | Correlation Between Preoperative Images of PPGL and Intraoperative Hemodynamics | completed | — | 159 | Peking Union Medical College HospitalOTHER | 1 | Nov 1, 2024 | clinicaltrials |
| NCT00843037 | Study Of Sunitinib In Patients With Recurrent Paraganglioma/Pheochromocytoma(SNIPP) | completed | Phase 2 | 25 | University Health Network, TorontoOTHER | 2 | Oct 17, 2024 | clinicaltrials |
| NCT02700230 | Vaccine Therapy in Treating Patients with Malignant Peripheral Nerve Sheath Tumor That is Recurrent or Cannot Be Removed by Surgery | completed | Phase 1 | 9 | Mayo ClinicOTHER | 1 | Sep 27, 2024 | clinicaltrials |
| NCT01379898 | Phenoxybenzamine Versus Doxazosin in PCC Patients(PRESCRIPT) | completed | Phase 4 | 134 | University Medical Center GroningenOTHER | 1 | Sep 19, 2024 | clinicaltrials |
| NCT04774289 | Incidence of Malignant Peripheral Nerve Sheath Tumor (MPNST) Development in Participants With Neurofibromatosis Type 1 (NF1) Receiving and Not Receiving Medical Therapies Directed at Plexiform Neurofibromas (PN) | completed | — | 296 | National Cancer Institute (NCI)NIH | 1 | Sep 19, 2024 | clinicaltrials |
| NCT00655655 | Everolimus and Vatalanib in Treating Patients With Advanced Solid Tumors | completed | Phase 1 | 96 | Mayo ClinicOTHER | 1 | Aug 21, 2024 | clinicaltrials |
| NCT05053685 | Metanephrines in Obstructive Sleep Apnoea | completed | — | 81 | Changi General HospitalOTHER | 1 | Aug 21, 2024 | clinicaltrials |
| NCT04860700 | The Efficacy and Safety of Anlotinib in Patients With Metastatic Pheochromocytoma or Paraganglioma | completed | Phase 2 | 27 | Peking Union Medical College HospitalOTHER | 1 | Jun 12, 2024 | clinicaltrials |
| NCT03531814 | Medication Adherence in Children, Adolescents and Adults With Neurofibromatosis Type 1(NF1) on Clinical Treatment Trials | completed | N/A | 12 | National Cancer Institute (NCI)NIH | 1 | Jun 11, 2024 | clinicaltrials |
| NCT00970970 | Visualizing Vascular Endothelial Growth Factor (VEGF) Producing Lesions in Von Hippel-Lindau Disease(VHLimage) | completed | — | 22 | University Medical Center GroningenOTHER | 1 | May 6, 2024 | clinicaltrials |
| NCT05438290 | DPCP to Treat Cutaneous Neurofibromas Associated With NF1 | completed | Phase 1 | 17 | Nicholas GulatiOTHER | 1 | May 6, 2024 | clinicaltrials |
| NCT03326388 | Intermittent Dosing Of Selumetinib In Childhood NF1 Associated Tumours(INSPECT) | completed | Phase 1 / Phase 2 | 14 | Great Ormond Street Hospital for Children NHS Foundation TrustOTHER | 1 | Apr 4, 2024 | clinicaltrials |
| NCT03008369 | Lenvatinib in Treating Patients With Metastatic or Advanced Pheochromocytoma or Paraganglioma That Cannot Be Removed by Surgery | completed | Phase 2 | 3 | Mayo ClinicOTHER | 1 | Feb 20, 2024 | clinicaltrials |
| NCT02839720 | Selumetinib in Treating Patients With Neurofibromatosis Type 1 and Cutaneous Neurofibroma | completed | Phase 2 | 11 | National Cancer Institute (NCI)NIH | 1 | Dec 6, 2023 | clinicaltrials |
| NCT03176693 | Preoperative Alpha Blockade for Pheochromocytoma | completed | Phase 3 | 39 | University of California, Los AngelesOTHER | 1 | Nov 20, 2023 | clinicaltrials |
| NCT02584309 | Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma | completed | Phase 2 | 73 | Washington University School of MedicineOTHER | 1 | Nov 7, 2023 | clinicaltrials |
| NCT06037135 | Dexmedetomidine Infusion During Laparoscopic Adrenalectomy | completed | N/A | 40 | Yonsei UniversityOTHER | 1 | Oct 6, 2023 | clinicaltrials |
| NCT05942482 | Head and Neck Paragangliomas: A 16-year Experience of a University Hospital in Turkey | completed | — | 39 | Pamukkale UniversityOTHER | 1 | Sep 15, 2023 | clinicaltrials |
| NCT03009201 | Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery | completed | Phase 1 | 16 | OHSU Knight Cancer InstituteOTHER | 1 | Aug 16, 2023 | clinicaltrials |
| NCT05858177 | The Efficacy and Safety of Temozolomide in Patients With MPPGL(MPPGL) | completed | Phase 2 | 62 | Peking Union Medical College HospitalOTHER | 1 | May 15, 2023 | clinicaltrials |
| NCT05803330 | Study of Alpha-blockers Alone During Preoperative Preparation in Patients With Pheochromocytoma | completed | N/A | 95 | Kunwu Yan,MMOTHER | 0 | Apr 7, 2023 | clinicaltrials |
| NCT02186678 | Comparison of Diagnostic Performances of 68Ga-DOTATATE PET-CT and 18F-FDOPA PET-CT in Paragangliomas and Pheochromocytomas Evaluation(DOTATATE) | completed | N/A | 30 | Assistance Publique Hopitaux De MarseilleOTHER | 1 | Apr 6, 2023 | clinicaltrials |
| NCT04435665 | NFX-179 Topical Gel Treatment in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF) | completed | Phase 2 | 48 | NFlection Therapeutics, Inc.INDUSTRY | 1 | Aug 9, 2022 | clinicaltrials |
| NCT01371201 | First International Randomized Study in Malignant Progressive Pheochromocytoma and Paraganglioma(FIRSTMAPPP) | completed | Phase 2 | 78 | Gustave Roussy, Cancer Campus, Grand ParisOTHER | 4 | Aug 4, 2022 | clinicaltrials |
| NCT01949714 | Effect of Chronic Catecholamine Overproduction on Brown Adipose Tissue | completed | — | 10 | University of AarhusOTHER | 1 | May 23, 2022 | clinicaltrials |
| NCT00346164 | Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma | completed | Phase 3 | 588 | Children's Oncology GroupNETWORK | 5 | Apr 28, 2022 | clinicaltrials |
| NCT05082311 | Cardiac and Vascular Changes in Pheochromocytoma and Paraganglioma(PheoCard) | completed | — | 55 | Sanjay Gandhi Postgraduate Institute of Medical SciencesOTHER_GOV | 1 | Feb 10, 2022 | clinicaltrials |
| NCT02452554 | Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial Sarcoma | completed | Phase 2 | 62 | Children's Oncology GroupNETWORK | 1 | Jan 13, 2022 | clinicaltrials |
| NCT01532687 | Gemcitabine With or Without Pazopanib in Treating Patients With Refractory Soft Tissue Sarcoma | completed | Phase 2 | 54 | OHSU Knight Cancer InstituteOTHER | 1 | Sep 27, 2021 | clinicaltrials |
| NCT04320589 | the Effect of Dexmedetomidine and Magnesium Sulfate in Open Resection of Pheochromocytoma | completed | Phase 2 | 30 | National Cancer Institute, EgyptOTHER | 1 | Sep 1, 2021 | clinicaltrials |
| NCT04557072 | Selective Versus Nonselective Alpha-blockade Prior to Pheochromocytoma Resection - Systematic Review and Meta-analysis | completed | — | 1,344 | Jagiellonian UniversityOTHER | 1 | Jun 18, 2021 | clinicaltrials |
| NCT01800032 | PET/MRI in CNS and Extra-CNS Tumors of Patients With Neurofibromatosis-1 (NF1) | completed | — | 30 | UNC Lineberger Comprehensive Cancer CenterOTHER | 1 | May 12, 2021 | clinicaltrials |
| NCT01967576 | Phase II Study of Axitinib (AG-013736) With Evaluation of the VEGF-pathway in Metastatic, Recurrent or Primary Unresectable Pheochromocytoma/Paraganglioma | completed | Phase 2 | 14 | National Cancer Institute (NCI)NIH | 1 | Jan 6, 2021 | clinicaltrials |
Data updated yesterdaySource updated Sep 28, 2026source: clinicaltrials